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#CES2024, #JPM2024, Mergers & Acquisitions Charge Stocks Forward On Monday – $AMAM $AXNX $HARP $INDP $LTRN $MODD $NVDA $SIDU Rise!

By John F. Heerdink, Jr.
Quote of the Day — “Measure what is measurable, and make measurable what is not so.” – Galileo Galilei



Happy  Monday!

I hope that you have kicked off the week in a great way. Here in San Francisco, the 42nd Annual JPMorgan Healthcare Conference #JPM2024 is now in full swing this week (Jan. 8-11) and deals are flying around town in this sector. In fact, today from the sector, Merck (NYSE: MRK), known as MSD outside of the United States and Canada, and Harpoon Therapeutics, Inc. (Nasdaq: HARP, $22.36, +111.94%) announced that the companies have entered into a definitive agreement under which Merck, through a subsidiary, will acquire Harpoon for $23.00 per share in cash for an approximate total equity value of $680 million. Also, Ambrx Biopharma, Inc., or Ambrx (NASDAQ: AMAM, $27.47, +101.54%), today announced that it has entered into a definitive agreement pursuant to which Johnson & Johnson (JNJ) will acquire all of the outstanding shares of Ambrx for $28.00 per share in cash, representing an approximately 105% premium to Ambrx’s closing stock price on January 5, 2024, for a total equity value of approximately $2.0 billion. Lastly, Boston Scientific Corporation (NYSE: BSX) today announced it has entered into a definitive agreement to acquire Axonics, Inc. (Nasdaq: AXNX, $69.26, +20.48%), a publicly traded medical technology company primarily focused on the development and commercialization of differentiated devices to treat urinary and bowel dysfunction. The purchase price is $71 in cash per share, reflecting an equity value of approximately $3.7 billion and an enterprise value of approximately $3.4 billion. Lots of action and flowing again in this sector and I believe allot more will be served as we move forward this week and beyond as all are building pipelines. Note, that our sister organization Tribe Public will be hosting a RSVP-ONLY FREE CEO Presentation Luncheon Event Tribe titled “DISCOVER HOW AI IS CRUSHING TIMELINES & COSTS IN THE BIOTECH SECTOR” at 1pm in the San Francisco during the JP Morgan Healthcare conference on Thursday, Jan 11 with co-host Panna Sharma, the President, CEO, and Board Member of Lantern Pharma Inc. (NASDAQ: LTRN, $4.37, +7.11%), an artificial intelligence (“AI”) company developing targeted and transformative cancer therapies using its proprietary RADR® AI and machine learning (“ML”) platform with multiple clinical stage drug programs.  If interested in attending, please send an email to research@tribepublic.com to get details. Overall today, stocks that make up the SPDR S&P Biotech ETF (XBI) closed at $93.42, +4.61%. The iShares Biotechnology ETF (IBB) closed at $139.39,+2.40% after recently establishing a new 52-wk low of $111.83. The 52-range is $111.83 – $138.74. The iShares U.S. Healthcare ETF (IYH) closed at $294.13, +.88%.  

As for the stock market, stocks moved significantly higher across the board as interest rates settled lowered with the 2-yr note closing at 4.35%, down 4bps & the 10-yr note yield closing at 4%, down 4bps.

Today’s macroeconomic schedule produced a single report today as the consumer credit report showed a rise by $23.7B in November. 

The US Dollar Index rose by .01% to close at $102.22. The CBOE Volatility Index (^VIX) closed at $13.08 and down 2.02% on the day and hit a high of $14.18 during intraday trading. 

At the end of today’s session the Dow 30 closed at 37,683.01 (+.58%). The S&P 500 closed at 4,763.54 (+1.41%) as the energy dropped a meaty 1.2% as oil prices fell 3.9% to close at $70.82 as stories flew around that our ‘good friends’ in Saudi Arabia were seeking to cut prices for February pointing towards of weakening demand. The Nasdaq closed at 14,843.77 (+2.20%), while Cathie Wood’s ARK Innovation ETF (ARKK) closed at $50.28, +2.82% as #CES2024, the most influential tech event in the world is taking place Jan. 9-12, in Las Vegas. The Magnificent Seven closed as follows: Alphabet (GOOG) closed at $140.53, +2.29%, Amazon (AMZN) closing at $149.10, +2.66%, Apple (AAPL) closing at $185.56, +2.42%, Meta Platforms (META) closing at $358.66, +1.91%, Microsoft (MSFT) closing at $374.69, +1.89%, NVIDIA (NVDA) closing at $522.53, +6.43% & Tesla (TSLA) closed at $240.45, +1.25%.

The small caps on the Russell 2000 closed at 1,989.01 (+1.94%).

The SPDR S&P Regional Banking ETF (KRE) closed at $52.21, +.93% and the SPDR S&P Bank ETF (KBE) closed at $46.09, +.92%.  

Around the crypto and precious metals’ tree, Bitcoin (BTC) traded to $46,787.18, +6.92% over the last 24 hours at the time of this writing and Coinbase Global (COIN) closed at $159.42, +3.53% (+379.31% over the last year). Gold prices closed at $2,037, -$12/oz. & silver closed at $23.22, -$.03/oz. on the day.  The SPDR Gold Shares ETF (GLD) closed at $187.87, -.78% today and up 8.15% over the last year.


MOVERS TODAY

Shares of Sidus Space (NASDAQ: SIDU), a multi-faceted Space and Data-as-a-Service company, closed at $15.32, +17.48% and is now up a whopping 73.89% YTD. On January 3,  Sidus Space announced that the National Oceanic and Atmospheric Administration (NOAA) has granted Sidus a Tier 1 remote sensing license to include Panchromatic (PAN) and Shortwave Infrared (SWIR) imaging capabilities. This approval includes Sidus’ upcoming LizzieSat™ scheduled for launch in March 2024, as well as subsequent LizzieSat satellites.


MEMES CENTRAL

Memes stock GameStop Corp. (GME) closed at $15.79, -1.07% as the shorts won their ongoing daily battle today. 

Shares of AMC, the largest movie exhibition company in the United States, the largest in Europe and the largest throughout the world with approximately 950 theaters and 10,500 screens across the globe, closed today at $5.29, +2.32% as the company announced recently that they had completed a $350M At-the Market Equity Offering and reduced debt by $62M. 


VP WATCHLIST UPDATES  


On Dec. 18, StoneCo Ltd. (Nasdaq: STNE, $17.46, +2.11%), a leading provider of financial technology and software solutions that empower merchants to conduct commerce seamlessly across multiple channels and help them grow their businesses, announced that it has obtained a commitment of US$467.5 million in the form of a revolving securitization facility from the United States International Development Finance Corporation (DFC), an agency of the United States government.

On Nov. 10, STNE reported its financial results for its third quarter ended September 30, 2023. They highlighted a strong quarter with Adjusted EBT reaching R$545 million, up 228% year over year, on accelerating MSMB TPV growth of 19.9%, resulting in Adjusted Net income of R$435 million, up 302% year over year.


Lantern (LTRN), closed at $4.37, 7.11%. Lantern is an Artificial Intelligence (AI) firm that is transforming the cost, pace, and timeline of oncology drug discovery and development and specifically is developing targeted and transformative cancer therapies using its proprietary RADR® AI and machine learning (“ML”) platform with multiple clinical stage drug programs.

On December 20, Target Oncology published an article called “LP-184 May Expand Options for Pancreatic Cancers With DDR Defects.” It begins as follows: LP-184, a novel drug with a unique mechanism targeting prostaglandin reductase 1 (PTGR1) and DNA repair pathways, represents a vital step in expanding treatment options for patients with advanced cancers, including pancreatic cancer, according to Igor Astsaturov, MD, PhD. Read the balance of the article here


On Nov. 30, Lantern announced that the U.S. Food and Drug Administration (FDA) has granted LP-284 Orphan Drug Designation (ODD) for the treatment of high-grade B-cell lymphoma with MYC and BCL2 rearrangements. Lantern highlighted that the Orphan Drug Designation strengthens LP-284’s clinical development path and can provide for additional market exclusivity and commercial protection, Lantern has initiated a first-in-human Phase 1 trial (NCT06132503) for LP-284 in B-cell non-Hodgkin’s lymphomas (NHL), including high-grade B-cell lymphoma (HGBL) and mantle cell lymphoma (MCL), & this Orphan Drug Designation marks the second such designation for drug-candidate LP-284 this year.


On Nov. 8, Lantern announced operational highlights and financial results for the third quarter ended September 30, 2023 highlighting the following: 

  • Received IND clearance from FDA to initiate Phase 1 clinical trial for LP-284, a first-in-human trial for advanced, refractory non-Hodgkin’s lymphomas (NHL). 
  • Dosed initial patient in Phase 1 with LP-184, a clinical trial for multiple advanced solid tumors that are refractory to standard-of-care therapies.
  • Progressed Phase 2 LP-300 Harmonic™ clinical trial towards enrollment in East Asian countries where 30-35+% of all lung cancer cases occur in never-smokers with NSCLC; continued expansion of additional clinical trial sites in the US and increased focus on recruitment activity with advocacy groups.
  • Developed initial proof-of-concept and preclinical evidence for a novel cryptophycin-based ADC (antibody-drug conjugate); initial data is planned to be shared in January 2024.
  • Furthered development of Lantern’s AI platform, RADR®, to include modules for the streamlined development of ADCs and the prediction of drug combinations with existing approved checkpoint inhibitors.
  • Approximately $45 million in cash, cash equivalents, and marketable securities as of September 30, 2023, is anticipated to provide a cash runway into at least Q3 of 2025.

As a quick follow up to Tribe Public’s recent CEO Presentation events that were held on the West Coast, our sister organization held a brief webinar-based Q&A session with Panna Sharma, CEO of Lantern, to have him address a few questions. The video has now ben published at the Tribe Public YouTube Channel the brief ~10-minute informative session can be viewed now by clicking here.

On Oct. 3, Lantern announced that in vivo data highlighting the enhanced efficacy of Lantern’s drug candidate LP-184 in glioblastoma (GBM) were published in Clinical Cancer Research, a journal of the American Association for Cancer Research. LP-184 is a unique small molecule with low nanomolar activity and favorable CNS penetration. LP-184 utilizes its powerful mechanism of action, known as synthetic lethality, to exploit common vulnerabilities in solid tumor and CNS cancers with DNA damage repair (DDR) deficiencies. In addition, Lantern’s AI platform, RADR®, has highlighted overlapping gene dependency profiles between GBM tumorigenesis and sensitivity to LP-184, such as EGFR activation pathways. The article, entitled “Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma” can be accessed here.

 

Panna Sharma is the President, CEO, and Board Member of Lantern Pharma Inc.

“The data highlighted in Clinical Cancer Research solidify LP-184 as a promising therapeutic for GBM, with LP-184 having inhibited the viability and growth of multiple GBM models including temozolomide-resistant and MGMT-expressing cells,” stated Panna Sharma, Lantern’s President and CEO.

“The rapid advancement of LP-184 into a first-in-human Phase 1 trial provides strong validation of the power of our AI-enabled approach to drug development. This approach is about more than just developing new treatments, it’s about making them more targeted, more effective, and ultimately doing all of this more efficiently. This publication demonstrates our ability to deliver on these aspirations and introduce new therapeutic programs in areas where there is significant unmet patient need.”



Shares of Indaptus Therapeutics, Inc. (Nasdaq: INDP) closed at $1.89, +6.04% and is up 2.21% at $1.94 in the aftermarket. Indaptus is a company with the ability to harness both the body’s innate and adaptive immune responses, believes that they are uniquely positioned to revolutionize the treatment of cancer and certain infectious diseases. Indaptus Therapeutics has evolved from more than a century of immunotherapy advances. The Company’s novel approach is based on the hypothesis that efficient activation of both innate and adaptive immune cells and pathways and associated anti-tumor and anti-viral immune responses will require a multi-targeted package of immune system-activating signals that can be administered safely intravenously (i.v.). Indaptus’ patented technology is composed of single strains of attenuated and killed, non-pathogenic, Gram-negative bacteria producing a multiple Toll-like receptor (TLR), Nucleotide oligomerization domain (Nod)-like receptor (NLR) and Stimulator of interferon genes (STING) agonist Decoy platform. The products are designed to have reduced i.v. toxicity, but largely uncompromised ability to prime or activate many of the cells and pathways of innate and adaptive immunity. Decoy products represent an antigen-agnostic technology that have produced single-agent activity against metastatic pancreatic and orthotopic colorectal carcinomas, single agent eradication of established antigen-expressing breast carcinoma, as well as combination-mediated eradication of established hepatocellular carcinomas and non-Hodgkin’s lymphomas in standard pre-clinical models, including syngeneic mouse tumors and human tumor xenografts.

Today, Jan. 4, Indaptus announced that the European Patent Office (EPO) has informed the company that it will grant a European patent related to the company’s platform technology, covering a composition that can be used in the prevention or treatment of viral infections. The patent, titled “Methods of Treatment of Infections Using Bacteria,” (Application 19 866 580.4) provides protections for the application of the Company’s Decoy technology platform alone or in combination with standards of care for the prevention or treatment of any viral infection. The EPO patent will be the second patent granted to Indaptus outside the United States for this application. Jeffrey Meckler, Indaptus Therapeutics CEO, commented, “The continued protection of our intellectual property both in the U.S. and abroad will provide a competitive advantage for the Company, which should ultimately drive significant shareholder value over time. We continue to explore the applications of our technology platform beyond solid tumors, for which we are currently engaged in a Phase 1 clinical trial, and look forward to updating our shareholders on scientific progress.”

In pre-clinical studies tumor eradication was observed with Decoy products in combination with anti-PD-1 checkpoint therapy, low-dose chemotherapy, a non-steroidal anti-inflammatory drug, or an approved, targeted antibody. Combination-based tumor eradication in pre-clinical models produced innate and adaptive immunological memory, involved activation of both innate and adaptive immune cells, and was associated with induction of innate and adaptive immune pathways in tumors after only one i.v. dose of Decoy product, with associated “cold” to “hot” tumor inflammation signature transition. IND-enabling, nonclinical toxicology studies demonstrated safe i.v. administration without sustained induction of hallmark biomarkers of cytokine release syndromes, possibly due to passive targeting to liver, spleen, and tumor, followed by rapid elimination of the product. Indaptus’ Decoy products have also produced significant single agent activity against chronic hepatitis B virus (HBV) and chronic human immunodeficiency virus (HIV) infections in pre-clinical models.

On Nov. 6, Indaptus announced interim data from the first cohort of four patients in the Phase 1 INDP-D101 trial of its lead compound, Decoy20. A broad expression of cytokines and chemokines associated with innate and adaptive anti-tumor immune responses was observed, while adverse events were generally tolerable and resolved within 30 minutes to three days. Decoy20 is designed to “re-set” the immune system’s response to cancer. The poster was presented on November 4, 2023, at the Society for Immunotherapy of Cancer in San Diego.

“We are impressed that we saw short-term induction of more than 50 cytokines, chemokines and biomarkers and believe this is unprecedented with a single agent. These early data support our long-standing hypothesis that the Decoy platform may induce robust immune responses across multiple types of immune cells that we believe are important for the eradication of solid tumors,” commented Indaptus CEO Jeffrey Meckler. Learn more here. 

Also, on Nov. 6, Indaptus announced financial results for the third quarter ended September 30, 2023 and provided a corporate update.

“We continue to be encouraged by early results from our first cohort of patients in the INDP-D101 trial evaluating Decoy20 for the treatment of solid tumors. As we recently reported and presented at the Society for Immunology in Cancer (SITC) conference, all four first cohort patients have maintained stable disease since receiving their single dose and presented evidence of immune activation, along with short-lived adverse events consistent with Decoy20’s mechanism of action, and we look forward to continuing to track them. In the meantime, we have already dosed our first patient in the second cohort, for which we have titrated the dose down in anticipation of a similar response. We continue to expect to have the second cohort completed by early 2024, which would provide guidance for the selection for the recommended Phase 2 dose for subsequent multi-dosing and combination studies, which are also planned for 2024,” said Jeffrey Meckler, Chief Executive Officer of Indaptus. “We are also fortunate to be receiving the benefit of our appointment of industry veteran, Roger Waltzman, M.D., as our Chief Medical Officer, who has already proven valuable even in this short period. We anticipate continuing to benefit from his expertise as we move forward with our Phase 1 trial and further develop the Decoy platform. In the meantime, we are prudently managing our cash position.”

On Sept, 29, Tribe Public hosted a Webinar Presentation and Q&A Event titled “Immunotherapy Reimagined” Indaptus Therapeutics’ (NASDAQ: INDP) CEO, Jeffrey Meckler delivered a presentation & also addressed a 5-10 minute Q&A session at the end of the presentation. You may view it now by clicking here. 



Learn more about Indaptus Therapeutics (NASDAQ: INDP) at the VP Watchlist page by clicking here.
 
 
Shares of ADT Inc. (ADT), the most trusted brand in smart home and small business security, closed at $6.66, +2.18%.

ADT released its third quarter 2023 financial results before the market open recently and beat expectations. They highlighted the following progress: Significant balance sheet improvement driven by divestiture of commercial business, Record high CSB recurring monthly revenue balance driven by strong retention, Improved capital efficiency with record revenue payback of 2.0 years, & Continued innovation in core smart home security markets and rationalization of solar footprint.

On Oct. 2, GTCR, a leading private equity firm, announced that it has closed the acquisition of ADT’s commercial security, fire and life safety security businessfrom ADT Inc. (“ADT”, NYSE: ADT). Moving forward as a standalone organization, ADT Commercial will rebrand as Everon. GTCR will partner with former Protection1 executives Dan Bresingham and Tim Whall, along with other members of ADTC leadership, to acquire the Company, one of the leading national providers of electronic security and fire safety services to commercial enterprises and multi-site national accounts. Mr. Bresingham, former leader of ADT’s commercial security, fire and life safety business, will become Chief Executive Officer of Everon and Mr. Whall will serve as an active director on the Company’s Board.
 
Shares of Seanergy Maritime Holdings Corp. (SHIP) closed at $7.31, -9.42%. Seanergy is known as a leading player in the global shipping industry, being the only pure-play Capesize ship owner publicly listed in the U.S. The company specializes in Capesize shipping, representing the largest dry bulk carriers globally. Seanergy’s operating fleet currently consists of 17 vessels (1 Newcastlemax and 16 Capesize), with an average age of approximately 12.7 years and an aggregate cargo-carrying capacity of approximately 3,054,820 deadweight tons (dwt). The company is incorporated in the Marshall Islands and has executive offices in Glyfada, Greece.
 On Dec. 14, Seanergy announced  that the Board of Directors of the Company (“BOD”) has authorized a new $25 million buyback program (the “Plan”) which can be utilized to repurchase the Company’s common shares and other securities. The Company will also fully repay its last remaining convertible note (the “Note”) pursuant to the terms of the Note. The Note bears a 5.5% coupon, it is the last from a series of convertible notes with aggregate original notional amount of $38.7 million and $3.2 million face value remains outstanding. The full repayment of the Note will preempt potential dilution upon conversion of the Note.
 
 

Brad Hansen CEO of Holu Hou Energy (HHE), a provider of design-to-service solar plus energy storage systems, including the breakthrough EnergyCluster product for the Multi-Dwelling Unit (“MDU”) residential property and single-family home markets, recently presented at our sister organization’s Tribe Public Webinar Presentation and Q&A Event titled “Discover How Multi-Dwelling Units Are Profitably Implementing Solar Energy Today.” The event video has now been published at the Tribe Public YouTube Channel and has been viewed over 6k times and can be viewed now by clicking on this link

Note that HHE was recognized as the 2023 winner of the Innovative Tech Company of the Year at the 13th annual Pacific Edge Business Achievement Awards Gala in Honolulu, Hawai’i. With operations in California, Hawai’i, Wisconsin, and Shanghai, HHE engineers proprietary storage system and control platform solutions, including a breakthrough HHE “EnergyCluster” technology that is key to the development of the Multi-Dwelling Unit Residential housing market that uniquely allows for sharing amongst local units of excess energy created by solar energy production. This technology uniquely solves the key problems for installing solar energy for MDU tenant units: tenant load variability and tenant churn. Thus, HHE is essentially good for all parties. It is a vital partner for investors and asset owners who are seeking MDU renewable energy solutions that create a new and significant multi-year revenue stream. For tenants, the adoption is non-disruptive and, in practice, allows for energy control and localized resiliency. 

On Nov. 2, Holu Hou Energy LLC announced that it is has closed a $20M construction financing facility in support of the construction of Hawaii’s largest solar and energy storage project pipeline. The funding will enable procurement of the materials and EPC resources to construct MDU projects slated for completion in the next 4-quarters. HHE’s EnergyCluster Technology has  reportedly enabled the Largest Non-Utility Solar Project Pipeline in Hawaii – Approaching $1.0 Billion in Value.

 
 
 
Modular Medical, Inc. (NASDAQ: MODD, $2.14, +18.89% and is up +6.07% at $2.27 in the aftermarket), is a development-stage medical device company that intends to launch the next generation of insulin delivery technology. Using its patented technologies, the company seeks to eliminate the tradeoff between complexity and efficacy, thereby making top quality insulin delivery both affordable and simple to learn. Their mission is to improve access to the highest standard of glycemic control for people with diabetes taking it beyond “superusers” and providing “diabetes care for the rest of us.” Modular Medical was founded by Paul DiPerna, a seasoned medical device professional and microfluidics engineer. Prior to founding Modular Medical, Mr. DiPerna was the founder (in 2005) of Tandem Diabetes and invented and designed its t:slim insulin pump. More information is available at https://modular-medical.com.

On Dec. 21, Modular Medical announced a collaboration agreement with Glooko, Inc., a global leader specializing in connected care and remote patient monitoring for diabetes. Integrating with Glooko will allow clinicians and patients to easily review insulin dosing data from the MODD1 pump, when commercially available. In addition, through Glooko’s platform, Dexcom CGMS users will be able to view their glucose levels in the same accessible format in conjunction with their pump data. Glooko’s platform has a broad installed base, which has been deployed in over 30 countries and 8,000 clinical locations. Jeb Besser, CEO of Modular Medical stated,  “We are extremely pleased to add the Glooko technology platform to our diabetes care system making it even easier and more cost effective for us to provide this important capability to our clinical and patient base. Glooko’s mission to improve health outcomes of people with chronic conditions through its personalized, intelligent, connected care platform fits perfectly with our vision of providing an easy to use, affordable delivery technology to give more patients access to better care.”

 
 
On Dec. 15, Tribe Public hosted a CEO Presentation and Q&A Webinar Event titled “Diabetes Care For The Rest Of Us”. The co-host for this event was James (Jeb) Besser the CEO of Modular Medical, Inc. (NASDAQ:MODD), a development-stage medical device company that intends to launch the next generation of insulin delivery technology. Using its patented technologies, the company seeks to eliminate the tradeoff between complexity and efficacy, thereby making top quality insulin delivery both affordable and simple to learn. Their mission is to improve access to the highest standard of glycemic control for people with diabetes taking it beyond “superusers” and providing “diabetes care for the rest of us.”  You may view the event video at the Tribe Public YouTube channel now by clicking here.


 
 
 
 
According to a Reuters story, Affirm Holdings (AFRM, $45.34, +5.42% & +400.44% over the last year) is offering its “buy now, pay later” loans for the first time at self-checkout kiosks at more than 4,500 Walmart (WMT) U.S. stores, the lender said on Tuesday, Dec. 19.
 



NAYA Biosciences Inc. (“NAYA”), a company which has recently signed a definitive merger agreement with INVO Bioscience (INVO) to establish an expanded, publicly-traded life science company dedicated to increasing patient access to breakthrough treatments in fertility, oncology, and regenerative medicine, announced on Dec. 11 that new data for its CD38-targeted Flex-NK™ Bispecific Antibody (NY-338, formerly CYT-338) for the treatment of Multiple Myeloma (MM) was published as an abstract in the 2023 American Society of Hematology’s (ASH) meeting supplement of Blood, in the “Multiple Myeloma: Prospective Therapeutic Trials” section. “NAYA is building a portfolio of differentiated clinical-stage oncology therapeutics, starting with two FLEX-NK™ bispecific antibodies acquired from Cytovia Therapeutics,” commented NAYA CEO Dr. Daniel Teper. “We are excited about this new data for our CD38-targeted antibody, which aims to address limitations with the current standard-of-care and offer new options for multiple myeloma patients.”

“The synergistic engagement of NK cells through NKp46 greatly enhances the immunotherapeutic effects of FLEX-NK™ bispecific antibodies, reducing NK cell fratricide, maintaining NK cell levels, and enhancing potency including reversal of NK cell dysfunction,” added Ola Landgren, MD, PhD, co-author of the abstract and Professor of Medicine, Chief of the Myeloma Division, and Leader of the Experimental Therapeutics Program at the University of Miami’s Sylvester Comprehensive Cancer Center. “The data supports initiation of clinical trials to evaluate this promising new therapy and makes it a potential best-in-class anti-CD38 therapeutic for multiple myeloma.”

Learn more about Naya by watching this Tribe Public video event titled “Accelerating Biotech Value Creation” Featuring NAYA Biosciences CEO Dr. Daniel Teper.


Sonos, Inc. (Nasdaq: SONO, $16.68, +3.60%) is one of the world’s leading sound experience brands.

On Nov. 30, Sonos, offering a comprehensive overview of the company’s Environmental, Social, and Governance (ESG) efforts. Included in the Report are actions made against Sonos’ Climate Action Plan, introduced in 2021, which serves as a framework to drive the company to carbon neutrality by 2030 and net zero by 2040. “We aim to build products and experiences that bring joy to people, and to do it in a responsible way. Our Listen Better Report outlines how we’re bringing thoughtful innovation to everything we do in pursuit of helping the world listen better,” said Patrick Spence, Sonos CEO. “This year, we expanded our portfolio by unveiling three products that tie together immersive sound and sustainable design.”

On Nov. 15 that its Board of Directors has authorized a common stock repurchase program of up to $200 million. Recently, it was reported that Sonos has expectations to generate over $100 million from a major new product introduction this year — possibly hinting at new headphones.

Investing & Inspiration

  1. “Measure what is measurable, and make measurable what is not so.” – Galileo Galilei
  2. “Seek the lofty by reading, hearing and seeing great work at some moment every day.” – Thornton Wilder
  3. “Everyone is a genius at least once a year. The real geniuses simply have their bright ideas closer together.” – Georg C. Lichtenberg
  4. “The great thing about getting older is that you don’t lose all the other ages you’ve been.” – Madeleine L’Engle
  5. “Cherish your human connections: your relationships with friends and family.” – Joseph Brodsky
  6. “Dream in a pragmatic way.” – Aldous Huxley
  7. “No one has a greater asset for his business than a man’s pride in his work.” – Hosea Ballou
  8. “In life, as in chess, forethought wins.” – Charles Buxton
  9. “Where there is no vision, there is no hope.” – George Washington Carver
  10. “When you arise in the morning, think of what a precious privilege it is to be alive – to breathe, to think, to enjoy, to love.” – Marcus Aurelius
  11. “Order and simplification are the first steps toward the mastery of a subject.” – Thomas Mann
  12. “It always seems impossible until it’s done.” – Nelson Mandel
  13. “Leadership is influence.” – John C. Maxwell
  14. “Civilization began the first time an angry person cast a word instead of a rock.”– Sigmund Freud
  15. “Failure will never overtake me if my determination to succeed is strong enough.” – Og Mandino
  16. “Do what you can, with what you have, where you are.” – Theodore Roosevelt
  17. “It’s remarkable how much long-term advantage people like us have gotten by trying to be consistently not stupid, instead of trying to be very intelligent.” – Charlie Munger
  18. “I’ve got some advice for the young: If you’ve got anything you really want to do, don’t wait until you’re 93.” – Charlie Munger
  19. “Feeling gratitude and not expressing it is like wrapping a present and not giving it.” – William Arthur Ward
  20. “There is an immeasurable distance between late and too late.” – Og Mandino
  21. “The future belongs to those who believe in the beauty of their dreams.” – Eleanor Roosevelt
  22. “We choose our joys and sorrows long before we experience them.” – Khalil Gibran
  23. “The undertaking of a new action brings new strength.” – Richard L. Evans
  24. “Hindsight is always twenty-twenty.” – Billy Wilder
  25. “I’m from the ‘less is more’ school. I had to be in the ‘more is more’ zone with ‘Dallas Buyers Club’, so I was out of my comfort zone, but I had to trust that.” – Jean-Marc Vallee
  26. “I paid more for the Dallas Cowboys than anyone prior than that had ever paid to get involved in sports. But I wanted to be a part of the future of the Dallas Cowboys.” – Jerry Jones
  27. “Trust yourself, you know more than you think you do.” – Benjamin Spock
  28. “It is not enough to have a good mind; the main thing is to use it well.” – Rene Descartes
  29. “Success in creating AI would be the biggest event in human history. Unfortunately, it might also be the last, unless we learn how to avoid the risks.” – Stephen Hawking
  30. “In the future, everyone will be famous for 15 minutes.” – Andy Warhol
  31. “Halloween is not only about putting on a costume, but it’s about finding the imagination and costume within ourselves.” – Elvis Duran
  32. “The dog that trots about finds a bone.” – Golda Meir
  33. “A loving heart is the truest wisdom.” – Charles Dickens
  34. “Out of difficulties grow miracles.” – Jean de la Bruyere
  35. “A leader is one who knows the way, goes the way, and shows the way.” – John C. Maxwell
  36. “I can, therefore I am.” – Simone Weil
  37. “Life is the art of drawing without an eraser.” – John W. Gardner
  38. “Kind words do not cost much. Yet they accomplish much.” – Blaise Pascal
  39. “The smallest deed is better than the greatest intention.” – John Burroughs
  40. “Following the light of the sun, we left the Old World.” – Christopher Columbus
  41. “If opportunity doesn’t knock, build a door.” – Milton Berle
  42. “The greatest use of a life is to spend it on something that will outlast it.” – William James
  43. “Happiness is not something ready made. It comes from your own actions.” – Dalai Lama
  44. “Just because something doesn’t do what you planned it to do doesn’t mean it’s useless.” – Thomas A. Edison
  45. “There are people who have money and people who are rich.” – Coco Chanel
  46. “The young man knows the rules, but the old man knows the exceptions.” – Oliver Wendell Holmes, Sr.
  47. “Let your mind alone, and see what happens.” – Virgil Thomson
  48. “I believe things cannot make themselves impossible.” – Stephen Hawking
  49. “There is nothing more uncommon than common sense.” – Frank Lloyd Wright 
  50. “To begin, begin.” – William Wordsworth
  51. “You can find peace amidst the storms that threaten you.” – Joseph B. Wirthlin
  52. “Everything that is made beautiful and fair and lovely is made for the eye of one who sees.” – Rumi
  53. “The secret of business is to know something that nobody else knows.” – Aristotle Onassis
  54. “Life is the art of drawing without an eraser.” – John W. Gardner
  55. “Learning never exhausts the mind.” – Leonardo da Vinci
  56. “Live as brave men; and if fortune is adverse, front its blows with brave hearts.” – Marcus Tullius Cicero
  57. “It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare
  58. “The end of labor is to gain leisure.” – Aristotle
  59. “Though we travel the world over to find the beautiful, we must carry it with us or we find it not.” – Ralph Waldo Emerson
  60. “Any sufficiently advanced technology is indistinguishable from magic.” – Arthur C. Clarke
  61. “Good questions outrank easy answers.” – Paul Samuelson
  62. “Experience is the teacher of all things.” – Julius Caesar
  63. To see things in the seed, that is genius.” – Lao Tzu
  64. “Lend yourself to others, but give yourself to yourself.” – Michel de Montaigne
  65. “People are not disturbed by things, but by the view they take of them.” – Epictetus
  66. “Knowledge comes, but wisdom lingers.” – Alfred Lord Tennyson
  67. “Hitch your wagon to a star.” – Ralph Waldo Emerson
  68. “If fear is cultivated it will become stronger, if faith is cultivated it will achieve mastery.” – John Paul Jones
  69. “Great minds discuss ideas; average minds discuss events; small minds discuss people.” –  Eleanor Roosevelt
  70. “Happiness is a direction, not a place.” – Sydney J. Harris
  71. “Don’t let making a living prevent you from making a life.” – John Wooden
  72. “The secret of your future is hidden in your daily routine.” – Mike Murdock
  73. “We boil at different degrees.” – Clint Eastwood
  74. “If we open a quarrel between past and present, we shall find that we have lost the future.” – Winston Churchill
  75. “Hope is patience with the lamp lit.” – Tertullian
  76. “All human wisdom is summed up in two words; wait and hope.” – Alexandre Dumas
  77. “Forgiveness is the key to action and freedom.” – Hannah Arendt
  78. “The unexamined life is not worth living.” – Socrates
  79. “I never think of the future – it comes soon enough.” – Albert Einstein
  80. “Today you are you! That is truer than true! There is no one alive who is you-er than you!” – Dr. Seuss
  81. “We live in a rainbow of chaos.” – Paul Cezanne
  82. “Real knowledge is to know the extent of one’s ignorance.” – Confucius
  83. “Better keep yourself clean and bright; you are the window through which you must see the world.” – George Bernard Shaw
  84. “Life consists not in holding good cards but in playing those you hold well.” – Josh Billings
  85. “The traveler sees what he sees, the tourist sees what he has come to see.” – Gilbert K. Chesterton
  86. “Goodness is the only investment that never fails.” – Henry David Thoreau
  87. “The return we reap from generous actions is not always evident.” – Francesco Guicciardini
  88. “Courage is knowing what not to fear.”– Plato
  89. “Freedom means the opportunity to be what we never thought we would be.” – Daniel J. Boorstin
  90. “Fishes live in the sea, as men do a-land; the great ones eat up the little ones.” – William Shakespeare
  91. “A man is what he thinks about all day long.” – Ralph Waldo Emerson
  92. “There are two ways of spreading light: to be the candle or the mirror that reflects it.” – Edith Wharton
  93. “We cannot live only for ourselves. A thousand fibers connect us with our fellow men.” – Herman Melville
  94. “Childhood is a short season” – Helen Hayes
  95. “Formula for success: rise early, work hard, strike oil.” – J. Paul Getty
  96. “The hardest arithmetic to master is that which enables us to count our blessings.” – Eric Hoffer
  97. “I fear not the man who has practiced 10,000 kicks once, but I fear the man who has practiced one kick 10,000 times.” – Bruce Lee
  98. “There are no shortcuts in evolution.” – Louis D. Brandeis
  99. “Hope is the only bee that makes honey without flowers.” – Robert Green Ingersoll
  100. “Our happiness depends on wisdom all the way.” – Sophocles
  101. “Life is the art of drawing without an eraser.” – John W. Gardner
  102. “Give light and people will find the way.” – Ella Baker
  103. “Without craftsmanship, inspiration is a mere reed shaken in the wind.” – Johannes Brahms
  104. “Either move or be moved.” – Ezra Pound
  105. “Time is but the stream I go a-fishing in.” – Henry David Thoreau
  106. “It’s easy to make a buck. It’s a lot tougher to make a difference.” – Tom Brokaw
  107. “If you can’t stand the heat, get out of the kitchen.” – Harry S Truman
  108. “Remember upon the conduct of each depends the fate of all.” – Alexander the Great
  109. “Silence is the sleep that nourishes wisdom.” – Francis Bacon
  110. “Have patience. All things are difficult before they become easy.” – Saadi
  111. “No man ever steps in the same river twice, for it’s not the same river and he’s not the same man.” – Heraclit
  112. “An effort made for the happiness of others lifts above ourselves.” – Lydia M. Child
  113. “It is amazing what you can accomplish if you do not care who gets the credit.” – Harry S Truman
  114. “If you do not think about your future, you cannot have one.” – John Galsworthy
  115. “Your own mind is a sacred enclosure into which nothing harmful can enter except by your permission.” – Arnold Bennett
  116. “There is always risk involved. You can’t be a capitalist only when there are investment profits but then a socialist when you experience losses.” – Cristina Kirchner
  117. “I hear, I know. I see, I remember. I do, I understand.” – Confucius
  118. “He has achieved success who has worked well, laughed often, and loved much.” – Elbert Hubbard
  119. “Nobody who ever gave his best regretted it.” – George Halas
  120. “We must not allow other people’s limited perceptions to define us.” – Virginia Satir
  121. “There is a wisdom of the head, and a wisdom of the heart.” – Charles Dickens
  122. “Perfection is the child of time.” – Joseph Hall
  123. “No matter what people tell you, words and ideas can change the world.” – Robin Williams
  124. “Find something you’re passionate about and keep tremendously interested in it.” – Julia Child
  125. “The glow of one warm thought is to me worth more than money.” – Thomas Jefferson
  126. “Between stimulus and response there is a space. In that space is our power to choose our response. In our response lies our growth and our freedom.” – Viktor E. Frankl
  127. “Progress lies not in enhancing what is, but in advancing toward what will be.” – Khalil Gibran
  128. “Cherish all your happy moments; they make a fine cushion for old age.” – Booth Tarkington
  129. “The most effective way to do it, is to do it.” – Amelia Earhart
  130. “If you’re going through hell, keep going.” – Winston Churchill
  131. “The only sure weapon against bad ideas is better ideas.” – Alfred Whitney Griswold
  132. “Words are, of course, the most powerful drug used by mankind.” – Rudyard Kipling
  133. “The more things change, the more they are the same.” – Alphonse Karr
  134. “Of all possessions a friend is the most precious.” – Herodotus
  135. “Everything has beauty, but not everyone sees it.” – Confucius
  136. “The man who is swimming against the stream knows the strength of it.” – Woodrow Wilson
  137. “Success is the sum of small efforts – repeated day in and day out.” – Robert Collier
  138. “You exist only in what you do.” – Federico Fellini
  139. “Most people have the will to win, few have the will to prepare to win.” – Bobby Knight
  140. “The true art of memory is the art of attention.” – Samuel Johnson
  141. The secret of happiness is something to do.” – John Burroughs
  142. “A will finds a way.” – Orison Swett Marden
  143. “To live is to think.” – Marcus Tullius Cicero
  144. “The sea hath fish for every man.” – William Camden
  145. “What is called genius is the abundance of life and health.” – Henry David Thoreau
  146. “Prosperity tries the fortunate, adversity the great.” – Rose Kennedy
  147. “No one can figure out your worth but you.” – Pearl Bailey
  148. “Let there be work, bread, water and salt for all.” – Nelson Mandela
  149. “When one paints an ideal, one does not need to limit one’s imagination.” – Ellen Key
  150. “Perfection is attained by slow degrees; it requires the hand of time.” – Voltaire
  151. “Time passes irrevocably.” – Virgil
  152. “The world of reality has its limits; the world of imagination is boundless.” – Jean-Jacques Rousseau
  153. “The time you enjoy wasting is not wasted time.” – Bertrand Russell
  154. “Mastering others is strength. Mastering yourself is true power.” – Lao Tzu
  155. “You begin with the possibilities of the material.” – Robert Rauschenberg
  156. “If you live to be a hundred, I want to live to be a hundred minus one day so I never have to live without you.” – A. A. Milne
  157. “The only way to discover the limits of the possible is to go beyond them into the impossible.” – Arthur C. Clarke
  158. “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha
  159. “Curiosity will conquer fear even more than bravery will.” – James Stephens
  160. “There are years that ask questions and years that answer.” – Zora Neale Hurston
  161. “The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller
  162. “Every failure is a step to success.” – William Whewell
  163. “If you aren’t fired with enthusiasm, you will be fired with enthusiasm.” – Vince Lombardi
  164. “Either you run the day or the day runs you.” – Jim Rohn
  165. “A computer once beat me at chess, but it was no match for me at kick boxing.” – Emo Philips
  166. “I attribute my success to this – I never gave or took any excuse.” – Florence Nightingale
  167. “I can’t change the direction of the wind, but I can adjust my sails to always reach my destination.” – Jimmy Dean
  168. “If you fell down yesterday, stand up today.” – H. G. Wells
  169. “The world breaks everyone, and afterward, some are strong at the broken places.” – Ernest Hemingway
  170. “The quality, not the longevity, of one’s life is what is important.” – Martin Luther King, Jr.
  171. “You can’t expect to hit the jackpot if you don’t put a few nickels in the machine.” – Flip Wilson
  172. “Put your heart, mind, and soul into even your smallest acts. This is the secret of success.” – Swami Sivananda
  173. “If the highest aim of a captain were to preserve his ship, he would keep it in port forever.” – Thomas Aquinas
  174. “The secret of your future is hidden in your daily routine.” – Mike Murdock
  175. “Happiness is not a matter of intensity but of balance, order, rhythm and harmony.” – Thomas Merton
  176. “Seek the lofty by reading, hearing and seeing great work at some moment every day.” – Thornton Wilder
  177. “Once you bring life into the world, you must protect it. We must protect it by changing the world.” – Elie Wiesel
  178. “Let us permit nature to have her way. She understands her business better than we do.” – Michel de Montaigne
  179. “Great minds have purposes; others have wishes.” – Washington Irving
  180. “The great thing about getting older is that you don’t lose all the other ages you’ve been.” – Madeleine L’Engle
  181. “If you’re alive, there’s a purpose for your life.” – Rick Warren
  182. “Dream in a pragmatic way.” – Aldous Huxley
  183. “The works must be conceived with fire in the soul but executed with clinical coolness.” – Joan Miro
  184. “Memories are the key not to the past, but to the future.” – Corrie Ten Boom
  185. “Great minds discuss ideas; average minds discuss events; small minds discuss people.” – Eleanor Roosevelt
  186. “Failure will never overtake me if my determination to succeed is strong enough.” – Og Mandino
  187. “I think about my work every minute of the day.” – Jeff Koons
  188. “I restore myself when I’m alone.” –  Marilyn Monroe
  189. “Success is peace of mind which is a direct result of self-satisfaction in knowing you did your best to become the best you are capable of becoming.” – John Wooden
  190. “Courage is found in unlikely places.” – J. R. R. Tolkien
  191. “The first wealth is health.” – Ralph Waldo Emerson
  192. “Courage is found in unlikely places.” – J. R. R. Tolkien
  193. “Do what you can, with what you have, where you are.” – Theodore Roosevelt
  194. “A good beginning makes a good end.” – Louis L’Amour
  195. “What you do today can improve all your tomorrows.” – Ralph Marston
  196. “One that would have the fruit must climb the tree.” – Thomas Fuller
  197. “Joy in looking and comprehending is nature’s most beautiful gift.” – Albert Einstein
  198. “The future belongs to those who believe in the beauty of their dreams.” – Eleanor Roosevelt
  199. “Never go to bed mad. Stay up and fight.” – Phyllis Diller
  200. “The undertaking of a new action brings new strength.” – Richard L. Evans
  201. “It’s kind of fun to do the impossible.” – Walt Disney
  202. “Real riches are the riches possessed inside.” – B. C. Forbes
  203. “Reject your sense of injury and the injury itself disappears.” – Marcus Aurelius
  204. “It is not enough to have a good mind; the main thing is to use it well.” – Rene Descartes
  205. “A leader is one who knows the way, goes the way, and shows the way.” – John C. Maxwell
  206. “It takes an endless amount of history to make even a little tradition.” – Henry James”It’s not what you pay a man, but what he costs you that counts.” – Will Rogers
  207. “Halloween is not only about putting on a costume, but it’s about finding the imagination and costume within ourselves.” – Elvis Duran
  208. “Everything in the world may be endured except continual prosperity.” – Johann Wolfgang von Goethe
  209. “Where is all the knowledge we lost with information?” – T. S. Eliot
  210. “All I ask is the chance to prove that money can’t make me happy.” – Spike Milligan
  211. “Out of difficulties grow miracles.” – Jean de la Bruyere
  212. “Nine-tenths of wisdom is being wise in time.” – Theodore Roosevelt
  213. “Time is money.” – Benjamin Franklin
  214. “I can, therefore I am.” – Simone Weil
  215. “Where there is no vision, there is no hope.” – George Washington Carver
  216. “Greatness is a road leading towards the unknown.” – Charles de Gaulle
  217. “Kind words do not cost much. Yet they accomplish much.” – Blaise Pascal
  218. “The world is round so that friendship may encircle it.” – Pierre Teilhard de Chardin
  219. “Our deeds determine us, as much as we determine our deeds.” – George Eliot
  220. The greatest use of a life is to spend it on something that will outlast it.” – William James
  221. “Happiness is not something ready made. It comes from your own actions.” – Dalai Lama
  222. “If opportunity doesn’t knock, build a door.” – Milton Berle
  223. “I would define, in brief, the poetry of words as the rhythmical creation of Beauty.” – Edgar Allan Poe
  224. “There are people who have money and people who are rich.” – Coco Chanel
  225. “The young man knows the rules, but the old man knows the exceptions.” – Oliver Wendell Holmes, Sr.
  226. “The past always looks better than it was. It’s only pleasant because it isn’t here.” – Finley Peter Dunne
  227. “With the new day comes new strength and new thoughts.” – Eleanor Roosevelt
  228. “Give me the luxuries of life and I will willingly do without the necessities.” – Frank Lloyd Wright
  229. “To begin, begin.” – William Wordsworth
  230. “You can find peace amidst the storms that threaten you.” – Joseph B. Wirthlin
  231. “Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
  232. “Whenever you find yourself on the side of the majority, it is time to pause and reflect.” – Mark Twain
  233. “Adapt or perish, now as ever, is nature’s inexorable imperative.” – H. G. Wells
  234. “Won’t be long before we view gasoline cars the same way we view steam engines today.” – Elon Musk
  235. “The aim of life is to live, and to live means to be aware, joyously, drunkenly, serenely, divinely aware.” – Henry Miller
  236. “It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare“Opportunity is missed by most people because it is dressed in overalls and looks like work.” – Thomas A. Edison“Experience is one thing you can’t get for nothing.” – Oscar Wilde
  237. “Any sufficiently advanced technology is indistinguishable from magic.” – Arthur C. Clarke
  238. “Good questions outrank easy answers.” – Paul Samuelson
  239. “Thinking: the talking of the soul with itself.” – Plato
  240. “I don’t think of all the misery but of the beauty that still remains.” – Anne Frank
  241. “All money is a matter of belief.” – Adam Smith
  242. “People are not disturbed by things, but by the view they take of them.” – Epictetus
  243. “Uncertainty is seen to retard investment independently of considerations of risk or expected return.” – Ben Bernanke
  244. “I never called my work an ‘art’. It’s part of show business, the business of building entertainment.” – Walt Disney
  245. “Hitch your wagon to a star.” – Ralph Waldo Emerson
  246. “The greatest remedy for anger is delay.” – Lucius Annaeus Seneca
  247. “Great minds discuss ideas; average minds discuss events; small minds discuss people.” – Eleanor Roosevelt
  248. “Act as if what you do makes a difference. It does.” – William James
  249. “Success – keeping your mind awake and your desire asleep.” – Walter Scott
  250. “If I had to live my life again, I’d make the same mistakes, only sooner.” – Tallulah Bankhead
  251. “When one must, one can.” – Charlotte Whitton
  252. “Wealth consists not in having great possessions, but in having few wants.” – Epictetus
  253. “If we open a quarrel between past and present, we shall find that we have lost the future.” – Winston Churchill
  254. “Hope is patience with the lamp lit.” – Tertullian
  255. “A single sunbeam is enough to drive away many shadows.” – Francis of Assisi
  256. “With the past, I have nothing to do; nor with the future. I live now.” – Ralph Waldo Emerson
  257. “Laziness may appear attractive, but work gives satisfaction.” – Anne Frank
  258. “I never think of the future – it comes soon enough.” – Albert Einstein
  259. “Hope is but the dream of those who wake.” – Matthew Prior
  260. “The more sand that has escaped from the hourglass of our life, the clearer we should see through it.” – Jean Paul
  261. “Real knowledge is to know the extent of one’s ignorance.” – Confucius
  262. “Better keep yourself clean and bright; you are the window through which you must see the world.” – George Bernard Shaw
  263. “Nothing great in the world has ever been accomplished without passion.” – Georg Wilhelm Friedrich Hegel
  264. “History is a vast early warning system.” – Norman Cousins
  265. “We first make our habits, and then our habits make us.” – John Dryden
  266. “The traveler sees what he sees, the tourist sees what he has come to see.” – Gilbert K. Chesterton
  267. “Adventure is worthwhile.” – Aesop
  268. “We must build dikes of courage to hold back the flood of fear.” – Martin Luther King, Jr.
  269. “The return we reap from generous actions is not always evident.” – Francesco Guicciardini
  270. “Courage is knowing what not to fear.” – Plato
  271. “Science may never come up with a better office communication system than the coffee break.” – Earl Wilson
  272. “Progress was all right. Only it went on too long.” – James Thurber
  273. “If you would know strength and patience, welcome the company of trees.” – Hal Borland
  274. “We aim above the mark to hit the mark.” – Ralph Waldo Emerson
  275. “Hope is being able to see that there is light despite all of the darkness.” – Desmond Tutu
  276. “Our chief want is someone who will inspire us to be what we know we could be.” – Ralph Waldo Emerson
  277. “Patience is a virtue, and I’m learning patience. It’s a tough lesson.” – Elon Musk
  278. “Great things are done when men and mountains meet.” – William Blake
  279. “The man who has no imagination has no wings.” – Muhammad Ali
  280. “Formula for success: rise early, work hard, strike oil.” – J. Paul Getty
  281. “Action is the foundational key to all success.” – Pablo Picasso
  282. “Hope is like the sun, which, as we journey toward it, casts the shadow of our burden behind us.” – Samuel Smiles
  283. “The backbone of surprise is fusing speed with secrecy.” – Carl von Clausewitz
  284. “There are no shortcuts in evolution.” – Louis D. Brandeis
  285. “I am fascinated by what is beautiful, strong, healthy, what is living. I seek harmony.” – Leni Riefenstahl
  286. “If one advances confidently in the direction of his dreams, and endeavors to live the life which he has imagined, he will meet with a success unexpected in common hours.” – Henry David Thoreau
  287. “Waste no more time arguing about what a good man should be. Be one.” – Marcus Aurelius
  288. “It is during our darkest moments that we must focus to see the light.” – Aristotle Onassis
  289. “Courage is fear holding on a minute longer.” – George S. Patton
  290. “You must be the change you wish to see in the world.” – Mahatma Gandhi
  291. “Don’t judge each day by the harvest you reap but by the seeds that you plant.” – Robert Louis Stevenson
  292. “It is in the character of very few men to honor without envy a friend who has prospered.” – Aeschylus
  293. “Life is a series of natural and spontaneous changes. Don’t resist them – that only creates sorrow. Let reality be reality. Let things flow naturally forward in whatever way they like.” – Lao Tzu
  294. “The more you praise and celebrate your life, the more there is in life to celebrate.” – Oprah Winfrey
  295. “Anything simple always interests me.” – David Hockney
  296. “He who angers you conquers you.” – Elizabeth Kenny
  297. “Concision in style, precision in thought, decision in life.” – Victor Hugo
  298. “The secret of genius is to carry the spirit of the child into old age, which means never losing your enthusiasm.” – Aldous Huxley
  299. “View health as an investment, not an expense.” – John Quelch

“The most effective way to do it, is to do it.” – Amelia Earhart
“Man needs his difficulties because they are necessary to enjoy success.” – A. P. J. Abdul Kalam
“Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha
“Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
“You must do the things you think you cannot do.”- Eleanor Roosevelt
“Success is dependent on effort.” – Sophocles
“Nobody who ever gave his best regretted it.” – George Halas
“Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
“And when I breathed, my breath was lightning.” – Black Elk
“Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
“You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
“If you want a guarantee, buy a toaster.” – Clint Eastwood
“We are an impossibility in an impossible universe.” – Ray Bradbury
“If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
“I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
“Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
“It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
“Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
Surprise is the greatest gift which life can grant us.” – Boris Pasternak
“Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran
“Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
“All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
“There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” – Colin Powell
“There is more to life than increasing its speed.” – Mahatma Gandhi
“Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
“Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
“Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
“In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
“Life is too short for long-term grudges.” – Elon Musk
“There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
“Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
“The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
“Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
“Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
“But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
“Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
“Let there be work, bread, water and salt for all.” – Nelson Mandela
“The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
“A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
“I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
“It is the fight alone that pleases us, not the victory.” – Blaise Pascal
“If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
“Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
“Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
“Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
“You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
“Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
“Delete the negative; accentuate the positive!” – Donna Karan
“It’s crazy how fast time flies and how things progress.” – Nathan Chen
“The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
“Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
“Everything has beauty, but not everyone sees it.” – Confucius
“A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
“Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
“A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
“The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
“Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
“I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
“Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
“But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
“Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
“Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
“No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
“Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
“Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
“Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
“If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
“Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
“The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
“There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
“Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
“There is little that can withstand a man who can conquer himself.” – Louis XIV
“In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
“A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
“The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
“Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese
“Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
“Never do anything against conscience even if the state demands it.”– Albert Einstein
“Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
“The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
“In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
“A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
“The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
“Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
“Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
“Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
“No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch
“Start where you are. Use what you have. Do what you can.”– Arthur Ashe
“The secret of getting ahead is getting started.” – Mark Twain
“The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe

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