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Retailers Rule While Stocks Turn Red On Hump Day – $ANF $ATOS $BRQS $INVO $KSS $RETA $URBN $VIX Rise!

By John F. Heerdink, Jr.
Quote of the Day — “Either move or be moved.” – Ezra Pound

Happy Wednesday!

I hope that your hump day turned out to be very positive, wherever the world directed you.

As for the broad markets, the major indices ended the session in the red weighed down once again by the political posturing surrounding the US debt ceiling issues, while we await the Fed’s next interest decision in June & the earnings season rolls on.  A couple of key macroeconomic reports surfaced again today including the weekly MBA Mortgage Application Index report, which showed a 4.6% decline while purchase applications fell in concert by 4% & refinance applications fell even further by 5%.
The weekly EIA Crude Oil Inventories report confirmed a 12.46M barrel draw as oil prices continued to recover moving up 1.66% to close at $74.12 on Wednesday.  The yield curve stayed basically stayed in place again today as the 2-yr yield closed flat for the second day in a row at 4.34% & the 10-yr yield closed bumped up 2bps to close at 3.72%. The U.S. Dollar Index edged up anther .4% to end at 103.90.   

A few retailers had somewhat of a banner day to lead the market beating the street’s earnings expectations while guiding upward including Abercrombie & Fitch (ANF) that closed at $30.16, +31.1%, Kohl’s (KSS) that closed at $20.72, +7.5%, & Urban Outfitters (URBN) that closed at $31.35, +17.6%. However, despite their performance, the major indices closed lower at the end of the day. The S&P 500 closed at 4,115.24 (-.73%) with 10 of the eleven sectors closing in the red and the energy sector registering the lone win for the second consecutive day with a .5% move & rising on the strength of oil. Energy giant Chevron (CVX) closed at $157.25, +.27%. Related, Bloomberg reported that the number of fires burning in Canada’s top energy-producing province of Alberta continued to decline amid cooler weather, allowing more companies to restore oil and gas production that had been shut earlier in the month. The heavily-weighted and influential technology giant Apple (AAPL) closed at $174.84, +.16%. Reuters reported that the U.S. solicitor general on Tuesday urged the U.S. Supreme Court to reject an appeal by Apple and Broadcom stemming from their $1.1 billion trial loss to the California Institute of Technology in a patent infringement case. EV-maker Tesla (TSLA) pulled back to close at $182.90, -1.54%.

The Dow 30 closed at 32,799.92 (-.77%). Disney (DIS, $89.807, -.84%) as the Gov. DeSantis feud moves on.

The Nasdaq closed at 12,484.16 (-.61%), while Cathie Wood’s ARK Innovation ETF (ARKK) closed at $39.46, -.60%. 

The growth oriented small caps closed lower as the Russell 2000 closed at 1,767.00 (-1.16%) as did the MicroCaps as the Micro-cap ETF (IWC) closed at 104.67, -1.47%.

Banks stocks closed higher as The SPDR S&P Regional Banking ETF (KRE) fell 1.79% to close at $40.13 & the SPDR S&P Bank ETF (KBE) dropped 1.75% to close at $34.86.  

Biotech stocks dropped today. On the lower end of the biotech stocks spectrum, biotech stocks moved up as the SPDR S&P Biotech ETF (XBI) closed at $85.79, -1.94%.  The 52-wk range is $61.78 – $95.18. On the larger side of the biotech market, The iShares Biotechnology ETF (IBB) moved down to close at $129.28, -1.40%. The 52-range is $104.29 – $138.74. Shares of Reata Pharmaceuticals, Inc. (RETA), a global biopharmaceutical company focused on developing and commercializing novel therapies for patients with severe diseases, closed today at $95.36 up 20.37%. On May 10, Reata announced financial results for the first quarter of 2023 and provided an update on the Company’s business operations and clinical development programs. Warren Huff, Chief Executive Officer of Reata stated, “In the first quarter of 2023, we announced that the U.S. Food and Drug Administration (FDA) approved SKYCLARYS® (omaveloxolone) as the first and only FDA-approved drug indicated for the treatment of Friedreich’s ataxia (FA), a rare, genetic, debilitating, and degenerative neuromuscular disorder. This was a historic milestone for FA patients, their families, the FA support community, and Reata. Our commercial sales team has been in the field since early March, and we have completed the final stages of manufacturing and packaging commercial supplies of SKYCLARYS. We are encouraged by the significant interest from patients and health care providers to begin SKYCLARYS treatment and have already engaged a large segment of the neurology community in the brief time since the Company received approval.”

Lantern Pharma Inc. (NASDAQ: LTRN, $5.15), a clinical-stage biopharmaceutical company using its proprietary RADR® artificial intelligence (“AI”) and machine learning (“ML”) platform to transform the cost, pace, and timeline of oncology drug discovery and development, will be presenting at three of our sister organization’s Tribe Events in Scottsdale, Peoria, and Queen Creek, AZ on Thursday, May 25.

Please ping the Tribe at this link, if you are in the Scottsdale area and are interested in attending the noon complimentary CEO and Q&A Luncheon Event this week.

The iShares U.S. Healthcare ETF (IYH) closed at $272.06, -.65%.  

Around the crypto and precious metals’ tree, Bitcoin (BTC) traded to $26,403.19, -2.93% over the last 24 hours at the time of this writing. Gold prices closed still below 2k at $1,960, +$14.5/oz. & silver closed at $23.18, -.$44/oz. on the day. Two mining producers closed the day as follows: Hecla Mining Company (HL) closed at $5.28, -4.17% & First Majestic (AG, $5.95, -2.94%).

The CBOE Volatility Index (^VIX) closed at $20.03 up 8.09%. 


Shares of ADT Inc. (ADT), the most trusted brand in smart home and small business security, closed at $6.04, -1.63%. On May 2, ADT reported results for the first quarter of 2023 highlighting strong year-over-year growth in revenue; CSB and Commercial up 7% and 15%, respectively, versus prior year period, maintained record high customer retention and new record high recurring monthly revenue balance, improved capital efficiency with record revenue payback, & continued deleveraging with over $400 million debt reduction expected in 2023.

Shares of Seanergy Maritime Holdings Corp. (SHIP), the only pure-play Capesize ship-owner publicly listed in the US. Seanergy provides marine dry bulk transportation services through a modern fleet of Capesize vessels, closed at $4.49, -4.67%. On May 11, Seanergy Maritime announced that they successfully completed $54 million refinancing transactions for 3 Capesize Vessels with significant cost and liquidity benefits for the Company.  Seanergy will release its financial results for the first quarter ended March 31, 2023, prior to the open of the market in New York on Thursday, May 25, 2023.


Memes stock GameStop Corp. (GME) closed at $23.27, +.47% as the shorts won the ongoing daily battle. GME released financial results for the fourth quarter and fiscal year ended January 28, 2023 recently soundly beating earnings expectations coming in with Q4 adjusted profit of 16 cents vs. expected loss of 15 cents/share. Net sales were $2.226 billion, compared to $2.254 billion in the prior year’s fourth quarter. Selling, general and administrative (“SG&A”) expenses were $453.4 million, or 20.4% of sales, compared to $538.9 million, or 23.9% of sales, in the prior year’s fourth quarter. Net income was $48.2 million, compared to a net loss of $147.5 million for the prior year’s fourth quarter.

Shares of AMC, the largest movie exhibition company in the United States, the largest in Europe and the largest throughout the world with approximately 950 theaters and 10,500 screens across the globe, closed at $4.88, -2.98% and APE closed at $1.60, -1.23%.  AMC reported results for the first quarter ended March 31, 2023 on May 5 highlighted by total revenue growth of 21.5% to $954.4 million & a net loss improved by $101.9 million to $235.5 million.


The multi-billion-dollar global fertility market is predicted to reach approximately US$47.9 billion by 2030, yet remains severely underserved with many patients (upwards of 90% by many estimates) unable to access affordable treatment. INVO Bioscience, Inc. (NASDAQ: INVO, $.3610, +.53%) offers the INVOcell solution which provides an advanced, effective and affordable infertility treatment to help increase access to care. INVO is commercially advancing INVOcell through the opening of INVO Centers, opportunistically now pursuing acquisitions of established fertility (IVF) clinics in the U.S., and continuing to offer the technology to existing fertility practices.

On May 15, INVO announced financial results for the quarter ended March 31, 2023 and provided a business update. Steve Shum, CEO of INVO stated, “We made significant progress on nearly every key operational metric during the first quarter, particularly within our three existing INVO Centers in Atlanta, Birmingham and Monterrey achieving record levels of revenue and patient cycles. These three centers combined to generate $646,707 in revenue, an increase of 108% from the first quarter of the prior year and were ahead 46% sequentially from Q4 2022, as patients increasingly recognize and value the remarkable opportunity INVO offers to assist families with affordable fertility options. We are extremely pleased to see the existing clinics nearing break-even and look forward to each of them generating positive cashflows and profits in the near future. Tampa Fertility Institute, our planned INVO Center in Tampa, is progressing with a mid-summer target opening and we are also executing on the early preparation work for an INVO Center in Kansas City. To build on the success we are achieving with our INVO Centers, we expanded our commercialization approach to include the acquisition of established and profitable US IVF clinics and announced the execution of binding agreements to acquire Wisconsin Fertility Institute,” Shum continued. “We view our acquisition strategy as highly complementary to our ongoing efforts to build new INVO Centers, increase sales of our INVOcell® device and expand adoption of the IVC procedure. We expect this strategy to accelerate our corporate development efforts and our path to profitability, as we integrate IVC alongside IVF. We view these two procedures as highly complementary to each other and to our mission of expanding access and affordability for the millions of people for whom the cost of IVF is out of reach. We look forward to closing the acquisition in the current quarter.”

On April 18, Maxim Group’s Analyst Jason McCarthy, Ph.D. issued a BUY rating on INVO Bioscience (INVO). His report is titled, “4Q Results and Outlook: Fertility Space Remains Active as INVO Expands Strategy with IVF Clinic Acquisition.” His 12-month Price Target is $3. 

On April 5, INVO announced that it congratulates recently acquires Wisconsin Fertility Institute on being named one of America’s Best Fertility Clinics by Newsweek. During the survey period from November to December 2022, Newsweek and Statista invited over 3,000 reproductive endocrinologists, infertility specialists, obstetricians/gynecologists working in and referring patients to fertility clinics, other medical professionals (e.g., registered nurses, laboratory assistants) and fertility clinic administrators/managers working in fertility clinics to participate in the survey. Participants were asked to assess the quality in five categories for each recommended facility and to assign a ranking position to a set of fertility clinics. Only facilities defined as fertility clinics and ART (“Advanced Reproductive Technology”) providers by the Centers for Disease Control and Prevention (CDC) were considered. Click here for a full listing and methodology for inclusion.

On March 27, INVO Bioscience announced the closing of its previously announced registered direct offering of 3,680,000 shares of common stock (or pre-funded warrants in lieu thereof), priced at-the-market under Nasdaq rules. In a concurrent private placement, the Company also issued warrants to purchase up to an aggregate of 5,520,000 shares of common stock. The combined effective offering price for each share of common stock (or pre-funded warrant in lieu thereof) and warrant is $.815. The warrants are immediately exercisable, expire on the eight-year anniversary of the issuance date and have an exercise price of $0.63 per share. Maxim Group LLC is acting as the sole placement agent for the offering.

On Jan. 16, BioSpectrum published an article titled “INVO Bioscience introduces next-gen technologies to fertility market in Taiwan.”

On Jan. 5, INVO Bioscience announced it has entered an exclusive distribution agreement with Ming Mei Technology Co. Ltd (“Ming Mei”) for Taiwan. The agreement will have an initial 1-year term with renewals. Ming Mei is a leading distributor of fertility-based devices and components in Taiwan helping to bring the latest and most advanced medical equipment into the region. Ming Mei estimates it has approximately 90% coverage of reagents and consumables in the reproductive medicine market in Taiwan. With strong customer relationships in the region, and their familiarity with the field of reproductive medicine, Ming Mei is ideally suited to expand distribution of INVOcell in Taiwan. Taiwan is a destination for assisted reproductive technology (ART) throughout Asia and also has the lowest birthrate in the world. Taiwan’s birth rate has dropped as a result of similar trends elsewhere in Asia, such as later marriage and increasing cost of living. Further, the average age of patients requiring therapy is rising. Fortunately, according to the statistics published by “ICMART”, the overall implantation rate of therapy in Taiwan ranked second worldwide, almost equal to the level in the U.S., and a leading country in Asia. The stable high success rate derives from updated medical research and enriched clinical experience from the physicians, advanced laboratory facilities and technology as well as patient-centered customized treatment plans (depending on their age, ovarian functions and causes of infertility, etc.). Prior to the pandemic, in 2019 there were approximately 55,000 ART cases in Taiwan, an increase of approximately 55% compared to 2016. In July 2021, the government in Taiwan implemented a subsidy plan for ART with the goal of encouraging more local married couples to undergo ART treatments. The subsidies are also available to transnational couples in which one spouse holds a Taiwanese ID card.

On Jan. 3, INVO announced it has signed an agreement with Shelly W. Holmström, M.D. FACOG, to serve as the physician operator for the Company’s soon to be opened Tampa, Florida INVO Center.

***INSIDER BUYING ALERT***– On Friday June 3, after the close, a number of Form 4’s were filed at www.sec.gov confirming that the CEO, COO, CFO and 5 members of the board of directors purchased shares at $.95/share on June 1, 2022. Here’s the link to view all of the share purchases. 

Today, shares of Borqs Technologies, Inc. (Nasdaq: BRQS) closed at $.2461, +2.12%. The 52-week range is $.1930 – $4.688.  

  • On April 26, Borqs Technologies published its Letter to Shareholders Regarding the Divestment of Solar Subsidiary. Dear Shareholders of Borqs Technologies, Inc.: The purpose of this letter is to help clarify the proposed divestment of our company’s ownership in Holu Hou Energy, LLC (“HHE”) and the implications that this transaction may have to Borqs and our shareholders. Why the divestment? As we have stated in prior press releases, the Committee on Foreign Investment in the United States (“CFIUS”) has notified our company by a letter dated December 13, 2022, that CFIUS has identified risks to US national security arising as a result of Borqs’s investment in HHE. CFIUS advised us that the national security risks arising as a result of Borqs’s investment transaction with HHE relate to foreign proximity to U.S. military personnel and installations through HHE’s physical access to customers and their facilities, including at off-base military housing. CFIUS therefore required Borqs and HHE to enter into a National Security Agreement with CFIUS, pursuant to which Borqs must divest its interests in HHE. Proactive steps by Borqs. Read the balance here: 
  • On April 20, Borqs announced that its subsidiary, Holu Hou Energy LLC (HHE), a provider of design-to-service solar plus energy storage systems, has signed a contract to install HHE’s HoluPower energy storage and solar photovoltaic (PV) systems on homes at Lendlease’s Island Palm Communities (IPC) in Honolulu, Hawaii. When completed, the project will be worth well into the nine figures in sales for HHE. Lendlease, a leading real estate and investment group that manages almost 8,000 homes for the U.S. Army on Oahu, is the purchaser of the electricity and the installations will come in the form of HHE’s EnergyCluster, where multiple residential units have their systems connected in an energy network or “cluster.” Excess solar generation from any unit’s system in the network that would normally be lost is directly shared in real time with other connected units that have load above solar generation. The benefit is that the optimized PV and energy storage systems can meet 75-80% or more of the overall residents’ energy needs while not exporting power to the utility grid. Lendlease and HHE began initial planning in 2021, which culminated in constructing a “pilot” project in May 2022. Since then, the pilot has been operating with outstanding results across six residential units. In a typical month, approximately a third of the total generated electricity is shared with other units in the “cluster” thereby solving issues related to vacancy and resident load variability, while proving out the superior value created through a clustered approach versus stand-alone systems. The savings realized by Island Palm Communities through deployment of HHE’s systems is being reinvested to enhance the housing and amenities Lendlease offers to military families on the installation. Additionally, residents now have resilient back-up power that can be utilized during grid outage events. These systems also take a load burden off the Oahu electric grid, which improves overall stability. Each residential unit will have approximately 10kW of PV and 25 kWh of energy storage, with six residences typically being connected in an HHE EnergyShare network. Construction is set to begin summer of 2023, with initial installations at the Aliamanu Military Reservation near Honolulu.

  • Shares of BRQS landed in the top ten Reddit Short Squeeze Mentions on Thursday, April 13.
  • On March 23, Borqs announced that the Company has appointed Donald R. Kendall, Jr. as the sole trustee (the “Trustee”) to a divestment trust established to manage the orderly divestment of Borqs’ ownership of Holu Hou Energy, LLC, (“HHE”) as required by the Committee on Foreign Investment in the United States (“CFIUS”). Mr. Kendall has an extensive background of over four decades in investment management, including his role as the Chairperson of the Special Committee of the Board of Directors of SolarCity supervising the sale of SolarCity to Tesla, Inc. in 2016 for $2.6 billion. Mr. Kendall currently serves as the Managing Director and CEO of Kenmont Capital Partners, LP, an investment management firm with an emphasis on energy, alternative energy and transportation and General Partner of New Climate Ventures, an early-stage venture capital fund that invests in innovative early-stage startups with a focus on carbon avoidance and reduction. Mr. Kendall currently serves on the board of Talos Energy Inc. and has served on the boards of SolarCity Corporation, American Midstream Partners, LP, Stream Gas & Electric, Ltd., and Syzygy Plasmonics Inc. “We’re very excited and honored to have Don accepting the appointment to head up the sale of our solar subsidiary. HHE has been growing its share in the Hawaiian solar market significantly since Borqs’ acquisition in October 2021. We believe HHE’s unique EnergyShare solution also has tremendous potential in California and the other parts of the U.S. With Don’s vast experiences in the energy industry, I have no doubt that he will be able to orchestrate a successful divestment for us and find a suitable partner for HHE, while adhering to all applicable CFIUS requirements. We expect to generate a considerable liquidity position for the Company from the sale which will directly contribute to Borqs’ shareholder value, stated Mr. Pat Chan, CEO of Borqs.

  • On March 13, Borqs announced that the Company has entered into the two/three-wheelers automotive space by developing the smart cluster dashboard and has successfully demonstrated the newly developed unit during the 2023 January CES Exhibition. The new smart cluster dashboard is installed on a two-wheeler and connected to the internet via the cellular network. The Company is partnering with Faspro Systems who will assist Borqs in sales and also support deployment in the region. As of October 2022, there are 14.38 million motorcycles and 8.43 million cars registered in Taiwan. That is, about 62 percent of Taiwanese 23.19 million population currently own a scooter. Full Year 2022 sales have been 752,631 units. The electric vehicle segment is growing moderately. he smart cluster dashboard, developed by Borqs’ design team, supports global cellular bands, dual-band Wifi and GPS. The unit enables the connected 2-wheeler to provide mobile telephony, data connectivity, vehicle diagnostics, location services, remote vehicle control, battery management, and sensing capabilities. Through a companion application on a smart phone, a user can locate and control the 2-wheeler, locate near-by charging/gas stations, etc. Connected to a cloud, a whole set of analytics and guidance can be provided to various stake holders. The smart cluster dashboard is modular in architecture and has ample I/Os for any custom design. Borqs having its core strength in development of cellular radios can support OEMs for system integration on the vehicles to get better connectivity

  • On March 8, Borqs announced that the Company has won a contract with a prominent North American company to develop and manufacture an Android 5G rugged waterproof handheld device to be deployed in industries such as agriculture, oil and mining, utilities and safety, etc. The device will feature a long-life 5G chipset that can be used until 2030. The Company has signed multiple contracts with the same customer to develop a suite of enterprise class rugged devices which will be launched initially in the North American and European markets, to be followed by other countries.
  • On March 6, Borqs announced its preliminary revenue for the year ended December 31, 2022 where the Company expects total revenue for the year ended December 31, 2022 to be $53-58 million, increased by over 79% compared to $29.6 million for the year ended December 31, 2021, driven by increased IoT sales globally and revenues from Holu Hou Energy (HHE), Borqs’ solar energy storage system subsidiary. Reportedly, while the revenue from Borqs’ IoT business is expected to be more than 80% of the total revenue, the HHE’s revenue has also increased significantly. The Company has not yet finalized its financial results for the full year ended December 31, 2022. These preliminary financial results reflect the company’s current estimates, based on information available to management as of the date of this release, and are subject to further changes upon completion of the company’s year-end closing and audit procedures.

Holu Hou Energy, LLC, a Delaware Corporation, brings state-of-the-art renewable energy and energy storage systems to the Single-Family Residential, Multi-Dwelling Unit Residential and Commercial building markets. With operations in California, Hawaii, Wisconsin and Shanghai, HHE engineers proprietary storage system and control platform solutions, including a breakthrough “HHE Energy Share” technology that is key to development of the Multi-Dwelling Unit Residential housing market. HHE is a vital partner for investors and asset owners that are seeking ESG solutions. For more information, visit www.holuhou.com.

As Borqs previously announced, the Company is in the process of negotiation with the U.S. government to divest their solar energy storage system subsidiary, Holu Hou Energy (HHE). The agreement with the Committee on Foreign Investment in the United States (“CFIUS”) is expected to be signed in March. HHE is considered a top ten solar energy storage supplier in Hawaii, and has been increasing its market share. The Company intends to divest this subsidiary based on the terms and timing in the agreement to be reached with CFIUS. In the meantime, the Company has been in active discussions with potential nationally recognized investment bankers that will be involved for the divestiture. Since Borqs’ financial support in HHE starting from October 2021, HHE has signed approximately $60 million in contracts as of the date of this press release and has a growing pipeline approaching half a billion dollars. Borqs believes this voluntary mitigation will enable the tremendous inherent value of HHE to be realized and that the divestment can be a profitable transaction for Borqs’ shareholders. 

  • On Dec.8, Borqs announced its subsidiary, Holu Hou Energy (HHE), has received multiple purchase orders for its HoluPower xP solar energy storage systems for installation at homeowner locations in the Greater San Diego area in California. These orders represent the first for the Company in California. Whereas in Hawaii HHE works to develop and construct Single-Family Residential projects as an “end to end” provider, the Company will target the California homeowner market through already existing channel partners that will sell and construct the projects. For Multi-Dwelling Unit (MDU) Residential properties in the State, the Company will initially target apartment owners, REITs and other MDU stakeholders directly, then partner with existing licensed contractors for system construction. HHE has been focused on the Hawaii market since it began commercial shipments in 2020, in order to become successfully established in the largest market in the United States based upon solar installation penetration. Now it is turning to California, the largest market in terms of size of available opportunity. HHE recently completed the testing and documentation required for the HoluPower xP to be listed as an approved product by the California Energy Commission. The Company expects to be listed by early January 2023, after which permitting and installations can commence. In Hawaii, Holu Hou Energy has quickly become a leader for solar energy storage systems in the Single-Family Residential market, and has essentially created the previously untapped Multi-Dwelling Unit (“MDU”) Residential market for renewable energy by virtue of its “EnergyShare” technology. The same leading product attributes will benefit MDU property owners and homeowners in California. The potential available MDU market in California is believed to be in the billions of dollars. EnergyShare enables networked systems to share excess generation behind their respective utility meters, a game-changer for improving the project economics for the MDU market, including for low-income housing, rental property units and Home Owners Association managed condominiums and town homes. EnergyShare enables more energy to be delivered to load, and fewer batteries to be installed than the standard approach of a unit-by-unit installation.
  • On Nov. 4, Borqs announced its subsidiary, Holu Hou Energy (HHE), has rolled out its next generation HoluPower xP energy storage system. The product is the first system capable of economically addressing the Multi-Dwelling Unit Residential market through EnergyShare, a unique application and advantage, enabling networked systems to share excess generation behind their respective utility meters. This has been a game-changer for improving the project economics for the MDU market, including for low-income housing, rental property units and Home Owners Association managed properties. EnergyShare enables more energy to be delivered to load, and fewer batteries needing to be installed than the standard approach of unit-by-unit installation.
  • According to a recent research report by BloombergNEF (BNEF), global energy storage installations are projected to reach a cumulative 411 gigawatts (or 1,194 gigawatt-hours) by the end of 2030, 15 times the 27GW/56GWh of storage that was online at the end of 2021. The anticipated accelerated growth of the US market follows the passage of the Inflation Reduction Act in August 2022. Besides the United States, many of other largest power markets in the world such as the EU, China and India have all passed legislation that incentivizes energy storage deployments.
Shares of Atossa Therapeutics (ATOS), a clinical-stage biopharmaceutical company seeking to develop innovative medicines in areas of significant unmet medical need in oncology with a current focus on breast cancer and lung injury caused by cancer treatments rose to an intraday high of $.8888 & closed at $.87, +3.82% on 1.07M shares of trading volume. 
On May 15, Atossa announced financial results for the fiscal quarter ended March 31, 2023, and provides an update on recent company developments. They highlighted their two Phase 2 trials investigating (Z)-endoxifen in neoadjuvant setting initiated and are enrolling patients, full enrollment of Phase 2 KARISMA mammographic breast density study expected by end of 2023, & that they ended first quarter 2023 with $103.9 million of cash and cash equivalents and no debt.
Atossa’s CEO, Steven Quay, M.D., Ph.D., presented at a Tribe Public even titled “Atossa Therapeutics (NASDAQ: ATOS) Redefining Breast Cancer Prevention and Treatment” on Thursday, May 4, 2023. Dr. Quay provided an update on the clinical development of Atossa’s proprietary Selective Estrogen Receptor Modulator (SERM), (Z)-endoxifen, which is currently being investigated in three separate Phase 2 studies. You may view the event at the following link at the Tribe Public YouTube Channel
On March 22, Atossa announced financial results for the fiscal quarter and fiscal year ended December 31, 2022 and provided an update on recent company developments. Key developments from Q4 2022 and year to date included the Initiation and First Patient Dosed in Phase 2 EVANGELINE Study – EVANGELINE (Endoxifen Versus exemestANe GosEreLIn), is our Phase 2 randomized non-inferiority study of (Z)-endoxifen compared to exemestane plus goserelin as a neoadjuvant treatment for premenopausal women with Grade 1 or 2 ER+ / HER2- breast cancer. Participants receive neoadjuvant treatment for up to six months, followed by surgery. Several FDA-approved neoadjuvant therapies exist for ER- breast cancers, but few exist for ER+ patients, which account for approximately 78% of breast cancers. We expect to enroll approximately 175 patients at up to 25 sites across the United States. READ MORE.

On March 21, Atossa and Quantum Leap Healthcare Collaborative™ announced that Atossa’s proprietary Selective Estrogen Receptor Modulator (SERM), (Z)-endoxifen, will be evaluated in a new study arm of the ongoing I-SPY 2 clinical trial. The I-SPY 2 TRIAL evaluates neoadjuvant treatments for locally advanced breast cancer and is a collaborative effort among academic investigators from major cancer research centers across the United States, Quantum Leap Healthcare Collaborative, the U.S. Food and Drug Administration, and the Foundation for the National Institutes of Health (FNIH) Cancer Biomarkers Consortium. Approximately 20 patients will be treated with (Z)-endoxifen for up to 24 weeks prior to surgery.


Shares of InMed Pharmaceuticals Inc. (INM), a leader in the research, development and manufacturing of rare cannabinoids, closed at $1.30, and has traded up to $1.35, +3.85% in the aftermarket.

  • Last week, I co-hosted 3 Tribe Public CEO & Presentation Luncheon Events in Newport Beach, CA, Slat lake City, CA and San Francisco, CA with Eric Adams CEO of InMed Pharmaceuticals (NASDAQ: INM), a pure-play rare cannabinoid company. The meetings were packed room & they received confirmation and understanding with regard to the 120% quarter-over-quarter revenue growth that InMed is enjoying in their commercial BayMedica subsidiary. Eric Adams recently stated, “In the last few months we have seen a noticeable increase in awareness, understanding and adoption of rare cannabinoids in the H&W sector, evidenced by leading companies expanding their product lines to include new formats and formulations using rare cannabinoids such as the non-psychoactive ingredient cannabichromene (“CBC”). We are encouraged by two consecutive periods of significant quarter over quarter revenue growth. We will continue to support growth in a fiscally prudent manner in this relatively nascent market, where product demand can be unpredictable. The combination of a pharmaceutical drug development pipeline, together with a revenue generating commercial operation that will be contributing to extending our cash runway makes InMed a unique company within the rare cannabinoid space.”
  • On March 28, InMed announced it has concluded enrollment of its Phase 2 clinical trial using investigational drug INM-755 cannabinol (“CBN”) cream for the treatment of patients with epidermolysis bullosa (“EB”), a rare genetic skin disease. The Phase 2 study, called INM-755-201-EB, enrolled 19 patients. All four subtypes of inherited EB, including EB Simplex, Dystrophic EB, Junctional EB, and Kindler Syndrome were accepted into the trial. The clinical trial is evaluating the safety of INM-755 cannabinol cream and its preliminary efficacy in treating symptoms of itch, pain, and wound healing in patients with epidermolysis bullosa. The study used a within-patient, double-blind design whereby matched index areas are randomized to INM-755 (cannabinol) cream or vehicle cream as a control. Results from this Phase 2 study of INM-755 CBN cream are expected to be released early calendar Q3 2023. “Enrollment completion of this Phase 2 clinical trial of a cannabinol formulation represents an important milestone for InMed and the scientific community studying rare cannabinoids,” said Eric A. Adams, InMed’s President and CEO. “As a class of compounds, we believe cannabinoids hold tremendous therapeutic potential for their innate interaction with the body, however, to date there have been limited evidence-based studies investigating their effects. Taking a rare cannabinoid formulation through several Ph 1 and Ph 2 clinical trials has been a major undertaking. We look forward to the data read-out in the summer, so we can evaluate our strategic options and next steps.”

Shares of Chinook Therapeutics, Inc. (KDNY), a biopharmaceutical company focused on the discovery, development and commercialization of precision medicines for kidney diseases, closed at $21.51, -.14%.

On May 16, Chinook announced it has entered a collaboration agreement with Ionis Pharmaceuticals, Inc. for the discovery, development and commercialization of an antisense oligonucleotide (ASO) therapy for a rare, severe chronic kidney disease with significant unmet medical need. The companies will leverage Chinook’s precision medicine approach and deep expertise in nephrology and Ionis’ extensive expertise in RNA-targeted therapeutics.

On April 13, Chinook announced the appointment of Robert W. Azelby to its Board of Directors. Mr. Azelby brings more than 20 years of executive leadership and commercial experience in the biopharmaceutical industry to Chinook.“We are thrilled to welcome Bob to Chinook’s board of directors as we advance our pipeline through key milestones in 2023 and beyond,” said Eric Dobmeier, president and chief executive officer of Chinook Therapeutics. “Bob brings significant industry experience in building and growing companies and commercially launching new therapies, including in nephrology. His strategic counsel will be invaluable as we continue to advance treatments for patients with rare, severe chronic kidney diseases.” Mr. Azelby has more than two decades of experience leading biotech companies through key periods of development. Most recently, he served as president and chief executive officer of Eliem Therapeutics, a biotechnology company focused on developing novel therapies for neurology disorders, where he led the company through early growth with a $190 million in financing and a successful IPO. Previously, he served as the president and chief executive officer and a member of the board of directors of Alder BioPharmaceuticals, Inc. where he negotiated the successful sale of the company to Lundbeck. Prior to that, Mr. Azelby served as executive vice president and chief commercial officer of Juno Therapeutics through its acquisition by Celgene, and spent 15 years at Amgen in commercial roles across their nephrology and oncology business units. Mr. Azelby currently serves on the board of Clovis Oncology. He holds an M.B.A. from Harvard Business School and a B.A. in Economics and Religious Studies from the University of Virgin.

Economic Reports

On Tuesday, the preliminary IHS Markit Manufacturing PMI report for May confirmed a drop to 48.5. The preliminary May IHS Markit Services PMI report also showed a rise to 55.1. The New home sales report also showed a 4.1% M/M rise in April to land it at a seasonally adjusted annual rate of 683k units, while on a Y/Y basis, new home sales have jumped 11.8%.

On Wednesday, the weekly MBA Mortgage Application Index report, which showed a 4.6% decline while purchase applications fell in concert by 4% & refinance applications fell even further by 5%.
The weekly EIA Crude Oil Inventories report confirmed a 12.46M barrel draw.

Investing & Inspiration

  1. “Either move or be moved.” – Ezra Pound
  2. “Time is but the stream I go a-fishing in.” – Henry David Thoreau
  3. “It’s easy to make a buck. It’s a lot tougher to make a difference.” – Tom Brokaw
  4. “If you can’t stand the heat, get out of the kitchen.” – Harry S Truman
  5. “Remember upon the conduct of each depends the fate of all.” – Alexander the Great
  6. “Silence is the sleep that nourishes wisdom.” – Francis Bacon
  7. “Have patience. All things are difficult before they become easy.” – Saadi
  8. “No man ever steps in the same river twice, for it’s not the same river and he’s not the same man.” – Heraclit
  9. “An effort made for the happiness of others lifts above ourselves.” – Lydia M. Child
  10. “It is amazing what you can accomplish if you do not care who gets the credit.” – Harry S Truman
  11. “If you do not think about your future, you cannot have one.” – John Galsworthy
  12. “Your own mind is a sacred enclosure into which nothing harmful can enter except by your permission.” – Arnold Bennett
  13. “There is always risk involved. You can’t be a capitalist only when there are investment profits but then a socialist when you experience losses.” – Cristina Kirchner
  14. “I hear, I know. I see, I remember. I do, I understand.” – Confucius
  15. “He has achieved success who has worked well, laughed often, and loved much.” – Elbert Hubbard
  16. “Nobody who ever gave his best regretted it.” – George Halas
  17. “We must not allow other people’s limited perceptions to define us.” – Virginia Satir
  18. “There is a wisdom of the head, and a wisdom of the heart.” – Charles Dickens
  19. “Perfection is the child of time.” – Joseph Hall
  20. “No matter what people tell you, words and ideas can change the world.” – Robin Williams
  21. “Find something you’re passionate about and keep tremendously interested in it.” – Julia Child
  22. “The glow of one warm thought is to me worth more than money.” – Thomas Jefferson
  23. “Between stimulus and response there is a space. In that space is our power to choose our response. In our response lies our growth and our freedom.” – Viktor E. Frankl
  24. “Progress lies not in enhancing what is, but in advancing toward what will be.” – Khalil Gibran
  25. “Cherish all your happy moments; they make a fine cushion for old age.” – Booth Tarkington
  26. “The most effective way to do it, is to do it.” – Amelia Earhart
  27. “If you’re going through hell, keep going.” – Winston Churchill
  28. “The only sure weapon against bad ideas is better ideas.” – Alfred Whitney Griswold
  29. “Words are, of course, the most powerful drug used by mankind.” – Rudyard Kipling
  30. “The more things change, the more they are the same.” – Alphonse Karr
  31. “Of all possessions a friend is the most precious.” – Herodotus
  32. “Everything has beauty, but not everyone sees it.” – Confucius
  33. “The man who is swimming against the stream knows the strength of it.” – Woodrow Wilson
  34. “Success is the sum of small efforts – repeated day in and day out.” – Robert Collier
  35. “You exist only in what you do.” – Federico Fellini
  36. “Most people have the will to win, few have the will to prepare to win.” – Bobby Knight
  37. “The true art of memory is the art of attention.” – Samuel Johnson
  38. The secret of happiness is something to do.” – John Burroughs
  39. “A will finds a way.” – Orison Swett Marden
  40. “To live is to think.” – Marcus Tullius Cicero
  41. “The sea hath fish for every man.” – William Camden
  42. “What is called genius is the abundance of life and health.” – Henry David Thoreau
  43. “Prosperity tries the fortunate, adversity the great.” – Rose Kennedy
  44. “No one can figure out your worth but you.” – Pearl Bailey
  45. “Let there be work, bread, water and salt for all.” – Nelson Mandela
  46. “When one paints an ideal, one does not need to limit one’s imagination.” – Ellen Key
  47. “Perfection is attained by slow degrees; it requires the hand of time.” – Voltaire
  48. “Time passes irrevocably.” – Virgil
  49. “The world of reality has its limits; the world of imagination is boundless.” – Jean-Jacques Rousseau
  50. “The time you enjoy wasting is not wasted time.” – Bertrand Russell
  51. “Mastering others is strength. Mastering yourself is true power.” – Lao Tzu
  52. “You begin with the possibilities of the material.” – Robert Rauschenberg
  53. “If you live to be a hundred, I want to live to be a hundred minus one day so I never have to live without you.” – A. A. Milne
  54. “The only way to discover the limits of the possible is to go beyond them into the impossible.” – Arthur C. Clarke
  55. “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha
  56. “Curiosity will conquer fear even more than bravery will.” – James Stephens
  57. “There are years that ask questions and years that answer.” – Zora Neale Hurston
  58. “The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller
  59. “Every failure is a step to success.” – William Whewell
  60. “If you aren’t fired with enthusiasm, you will be fired with enthusiasm.” – Vince Lombardi
  61. “Either you run the day or the day runs you.” – Jim Rohn
  62. “A computer once beat me at chess, but it was no match for me at kick boxing.” – Emo Philips
  63. “I attribute my success to this – I never gave or took any excuse.” – Florence Nightingale
  64. “I can’t change the direction of the wind, but I can adjust my sails to always reach my destination.” – Jimmy Dean
  65. “If you fell down yesterday, stand up today.” – H. G. Wells
  66. “The world breaks everyone, and afterward, some are strong at the broken places.” – Ernest Hemingway
  67. “The quality, not the longevity, of one’s life is what is important.” – Martin Luther King, Jr.
  68. “You can’t expect to hit the jackpot if you don’t put a few nickels in the machine.” – Flip Wilson
  69. “Put your heart, mind, and soul into even your smallest acts. This is the secret of success.” – Swami Sivananda
  70. “If the highest aim of a captain were to preserve his ship, he would keep it in port forever.” – Thomas Aquinas
  71. “The secret of your future is hidden in your daily routine.” – Mike Murdock
  72. “Happiness is not a matter of intensity but of balance, order, rhythm and harmony.” – Thomas Merton
  73. “Seek the lofty by reading, hearing and seeing great work at some moment every day.” – Thornton Wilder
  74. “Once you bring life into the world, you must protect it. We must protect it by changing the world.” – Elie Wiesel
  75. “Let us permit nature to have her way. She understands her business better than we do.” – Michel de Montaigne
  76. “Great minds have purposes; others have wishes.” – Washington Irving
  77. “The great thing about getting older is that you don’t lose all the other ages you’ve been.” – Madeleine L’Engle
  78. “If you’re alive, there’s a purpose for your life.” – Rick Warren
  79. “Dream in a pragmatic way.” – Aldous Huxley
  80. “The works must be conceived with fire in the soul but executed with clinical coolness.” – Joan Miro
  81. “Memories are the key not to the past, but to the future.” – Corrie Ten Boom
  82. “Great minds discuss ideas; average minds discuss events; small minds discuss people.” – Eleanor Roosevelt
  83. “Failure will never overtake me if my determination to succeed is strong enough.” – Og Mandino
  84. “I think about my work every minute of the day.” – Jeff Koons
  85. “I restore myself when I’m alone.” –  Marilyn Monroe
  86. “Success is peace of mind which is a direct result of self-satisfaction in knowing you did your best to become the best you are capable of becoming.” – John Wooden
  87. “Courage is found in unlikely places.” – J. R. R. Tolkien
  88. “The first wealth is health.” – Ralph Waldo Emerson
  89. “Courage is found in unlikely places.” – J. R. R. Tolkien
  90. “Do what you can, with what you have, where you are.” – Theodore Roosevelt
  91. “A good beginning makes a good end.” – Louis L’Amour
  92. “What you do today can improve all your tomorrows.” – Ralph Marston
  93. “One that would have the fruit must climb the tree.” – Thomas Fuller
  94. “Joy in looking and comprehending is nature’s most beautiful gift.” – Albert Einstein

“The future belongs to those who believe in the beauty of their dreams.” – Eleanor Roosevelt

“Never go to bed mad. Stay up and fight.” – Phyllis Diller

“The undertaking of a new action brings new strength.” – Richard L. Evans

“It’s kind of fun to do the impossible.” – Walt Disney

“Real riches are the riches possessed inside.” – B. C. Forbes

“Reject your sense of injury and the injury itself disappears.” – Marcus Aurelius

“It is not enough to have a good mind; the main thing is to use it well.” – Rene Descartes

“A leader is one who knows the way, goes the way, and shows the way.” – John C. Maxwell

“It takes an endless amount of history to make even a little tradition.” – Henry James”It’s not what you pay a man, but what he costs you that counts.” – Will Rogers

“Halloween is not only about putting on a costume, but it’s about finding the imagination and costume within ourselves.” – Elvis Duran

“Everything in the world may be endured except continual prosperity.” – Johann Wolfgang von Goethe

“Where is all the knowledge we lost with information?” – T. S. Eliot

“All I ask is the chance to prove that money can’t make me happy.” – Spike Milligan

“Out of difficulties grow miracles.” – Jean de la Bruyere

“Nine-tenths of wisdom is being wise in time.” – Theodore Roosevelt

“Time is money.” – Benjamin Franklin

“I can, therefore I am.” – Simone Weil

“Where there is no vision, there is no hope.” – George Washington Carver

“Greatness is a road leading towards the unknown.” – Charles de Gaulle

“Kind words do not cost much. Yet they accomplish much.” – Blaise Pascal

“The world is round so that friendship may encircle it.” – Pierre Teilhard de Chardin

“Our deeds determine us, as much as we determine our deeds.” – George Eliot

“The greatest use of a life is to spend it on something that will outlast it.” – William James

Happiness is not something ready made. It comes from your own actions.” – Dalai Lama

“If opportunity doesn’t knock, build a door.” – Milton Berle

“I would define, in brief, the poetry of words as the rhythmical creation of Beauty.” – Edgar Allan Poe

“There are people who have money and people who are rich.” – Coco Chanel

“The young man knows the rules, but the old man knows the exceptions.” – Oliver Wendell Holmes, Sr.

“The past always looks better than it was. It’s only pleasant because it isn’t here.” – Finley Peter Dunne
“With the new day comes new strength and new thoughts.” – Eleanor Roosevelt
“Give me the luxuries of life and I will willingly do without the necessities.” – Frank Lloyd Wright
“To begin, begin.” – William Wordsworth
“You can find peace amidst the storms that threaten you.” – Joseph B. Wirthlin
“Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
“Whenever you find yourself on the side of the majority, it is time to pause and reflect.” – Mark Twain
“Adapt or perish, now as ever, is nature’s inexorable imperative.” – H. G. Wells
“Won’t be long before we view gasoline cars the same way we view steam engines today.” – Elon Musk
“The aim of life is to live, and to live means to be aware, joyously, drunkenly, serenely, divinely aware.” – Henry Miller
“It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare“Opportunity is missed by most people because it is dressed in overalls and looks like work.” – Thomas A. Edison“Experience is one thing you can’t get for nothing.” – Oscar Wilde
“Any sufficiently advanced technology is indistinguishable from magic.” – Arthur C. Clarke
“Good questions outrank easy answers.” – Paul Samuelson
“Thinking: the talking of the soul with itself.” – Plato
“I don’t think of all the misery but of the beauty that still remains.” – Anne Frank
“All money is a matter of belief.” – Adam Smith
“People are not disturbed by things, but by the view they take of them.” – Epictetus
“Uncertainty is seen to retard investment independently of considerations of risk or expected return.” – Ben Bernanke
“I never called my work an ‘art’. It’s part of show business, the business of building entertainment.” – Walt Disney
“Hitch your wagon to a star.” – Ralph Waldo Emerson
“The greatest remedy for anger is delay.” – Lucius Annaeus Seneca
“Great minds discuss ideas; average minds discuss events; small minds discuss people.” – Eleanor Roosevelt
“Act as if what you do makes a difference. It does.” – William James
“Success – keeping your mind awake and your desire asleep.” – Walter Scott
“If I had to live my life again, I’d make the same mistakes, only sooner.” – Tallulah Bankhead
“When one must, one can.” – Charlotte Whitton
“Wealth consists not in having great possessions, but in having few wants.” – Epictetus
“If we open a quarrel between past and present, we shall find that we have lost the future.” – Winston Churchill
“Hope is patience with the lamp lit.” – Tertullian
“A single sunbeam is enough to drive away many shadows.” – Francis of Assisi
“With the past, I have nothing to do; nor with the future. I live now.” – Ralph Waldo Emerson
“Laziness may appear attractive, but work gives satisfaction.” – Anne Frank
“I never think of the future – it comes soon enough.” – Albert Einstein
Hope is but the dream of those who wake.” – Matthew Prior
“The more sand that has escaped from the hourglass of our life, the clearer we should see through it.” – Jean Paul
“Real knowledge is to know the extent of one’s ignorance.” – Confucius
“Better keep yourself clean and bright; you are the window through which you must see the world.” – George Bernard Shaw
“Nothing great in the world has ever been accomplished without passion.” – Georg Wilhelm Friedrich Hegel
“History is a vast early warning system.” – Norman Cousins
“We first make our habits, and then our habits make us.” – John Dryden
“The traveler sees what he sees, the tourist sees what he has come to see.” – Gilbert K. Chesterton
“Adventure is worthwhile.” – Aesop
“We must build dikes of courage to hold back the flood of fear.” – Martin Luther King, Jr.
“The return we reap from generous actions is not always evident.” – Francesco Guicciardini
“Courage is knowing what not to fear.” – Plato
“Science may never come up with a better office communication system than the coffee break.” – Earl Wilson
“Progress was all right. Only it went on too long.” – James Thurber
“If you would know strength and patience, welcome the company of trees.” – Hal Borland
“We aim above the mark to hit the mark.” – Ralph Waldo Emerson
“Hope is being able to see that there is light despite all of the darkness.” – Desmond Tutu
“Our chief want is someone who will inspire us to be what we know we could be.” – Ralph Waldo Emerson
“Patience is a virtue, and I’m learning patience. It’s a tough lesson.” – Elon Musk
“Great things are done when men and mountains meet.” – William Blake
“The man who has no imagination has no wings.” – Muhammad Ali
“Formula for success: rise early, work hard, strike oil.” – J. Paul Getty
“Action is the foundational key to all success.” – Pablo Picasso
“Hope is like the sun, which, as we journey toward it, casts the shadow of our burden behind us.” – Samuel Smiles
“The backbone of surprise is fusing speed with secrecy.” – Carl von Clausewitz
“There are no shortcuts in evolution.” – Louis D. Brandeis
“I am fascinated by what is beautiful, strong, healthy, what is living. I seek harmony.” – Leni Riefenstahl
“If one advances confidently in the direction of his dreams, and endeavors to live the life which he has imagined, he will meet with a success unexpected in common hours.” – Henry David Thoreau
“Waste no more time arguing about what a good man should be. Be one.” – Marcus Aurelius
“It is during our darkest moments that we must focus to see the light.” – Aristotle Onassis
“Courage is fear holding on a minute longer.” – George S. Patton
“You must be the change you wish to see in the world.” – Mahatma Gandhi
“Don’t judge each day by the harvest you reap but by the seeds that you plant.” – Robert Louis Stevenson
“It is in the character of very few men to honor without envy a friend who has prospered.” – Aeschylus
“Life is a series of natural and spontaneous changes. Don’t resist them – that only creates sorrow. Let reality be reality. Let things flow naturally forward in whatever way they like.” – Lao Tzu
“The more you praise and celebrate your life, the more there is in life to celebrate.” – Oprah Winfrey
“Anything simple always interests me.” – David Hockney
“He who angers you conquers you.” – Elizabeth Kenny
“Concision in style, precision in thought, decision in life.” – Victor Hugo
“The secret of genius is to carry the spirit of the child into old age, which means never losing your enthusiasm.” – Aldous Huxley
“View health as an investment, not an expense.” – John Quelch
“The most effective way to do it, is to do it.” – Amelia Earhart
“Man needs his difficulties because they are necessary to enjoy success.” – A. P. J. Abdul Kalam
“Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha
“Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
“You must do the things you think you cannot do.”- Eleanor Roosevelt
“Success is dependent on effort.” – Sophocles
“Nobody who ever gave his best regretted it.” – George Halas
“Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
“And when I breathed, my breath was lightning.” – Black Elk
“Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
“You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
“If you want a guarantee, buy a toaster.” – Clint Eastwood
“We are an impossibility in an impossible universe.” – Ray Bradbury
“If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
“I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
“Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
“It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
“Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
Surprise is the greatest gift which life can grant us.” – Boris Pasternak
“Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran
“Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
“All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
“There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” – Colin Powell
“There is more to life than increasing its speed.” – Mahatma Gandhi
“Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
“Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
“Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
“In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
“Life is too short for long-term grudges.” – Elon Musk
“There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
“Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
“The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
“Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
“Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
“But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
“Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
“Let there be work, bread, water and salt for all.” – Nelson Mandela
“The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
“A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
“I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
“It is the fight alone that pleases us, not the victory.” – Blaise Pascal
“If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
“Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
“Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
“Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
“You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
“Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
“Delete the negative; accentuate the positive!” – Donna Karan
“It’s crazy how fast time flies and how things progress.” – Nathan Chen
“The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
“Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
“Everything has beauty, but not everyone sees it.” – Confucius
“A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
“Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
“A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
“The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
“Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
“I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
“Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
“But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
“Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
“Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
“No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
“Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
“Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
“Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
“If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
“Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
“The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
“There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
“Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
“There is little that can withstand a man who can conquer himself.” – Louis XIV
“In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
“A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
“The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
“Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese
“Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
“Never do anything against conscience even if the state demands it.”– Albert Einstein
“Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
“The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
“In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
“A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
“The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
“Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
“Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
“Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
“No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch
“Start where you are. Use what you have. Do what you can.”– Arthur Ashe
“The secret of getting ahead is getting started.” – Mark Twain
“The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe