Markets Trade Tightly On Thursday As M&A & Earnings Hit The Tape- $AG $ATOS $CCXI $GBT $HL $INVO $KDNY $NBSE $XBI Rise!
Happy Thursday!
The stock market traded in a relatively tightly range as number earnings reports, news of buyouts, & oil prices declining ($88.49/bbl, -2.7%) continued to hit the worldwide web. In turn, the S&P 500 closed at 4,151.94 (-.08%) as the energy sector fell 3.6%. The Dow ended the session at 32,726.82 (-.26%). The growth oriented and tech heavy Nasdaq continued its upward move this week as it closed at 12,720.58 (+.41%) as advancing issuers led the declining issuers by a 7-5 margin. The small caps on the Russell 2000 closed slightly lower at 1,906.46 (-.13%). The MicroCaps, for the fourth consecutive day in the row, rose across the board as the iShares Micro-Cap ETF (IWC) closed at $118.60, +.97%, while Biotech stocks jumped upward again as the SPDR S&P Biotech ETF (XBI) closed at $88.71, +5.53%. The 52-wk range is now $61.78 – $136.61. The iShares Biotechnology ETF (IBB) also closed at $130.18, +2.24%. The 52-range is $104.29 – $177.37. A decent measure of the markets volatility or the CBOE Volatility Index (^VIX) closed down again at at $21.44, -2.32% and traded within the range of $21.44 – $22.66.
The macroeconomic schedule also delivered the initial jobless claims report for the week ending July 30 showed a 6k rise to 260k, while continuing claims for the week ending July 23 rose to 1.416M up 48k. The trade deficit also tightened to $79.6B. The Weekly EIA Natural Gas Inventories report confirmed a 41 bcf build. The yield curve remained inverted today and pulled back after yesterday’s jump as the 10-yr dropped 7 basis points to 2.68% & the 2-yr note dropped 6 basis points to close 3.04%.
Around the money and precious metals’ tree, the U.S. Dollar Index closed at 105.78, -.69%, while Bitcoin (BTC) bounced to $22,525.50, -3.52% over the last 24-hours at the time of this writing. Gold prices closed at $1,794/oz.,+$28/oz. & silver closed at $20.20/oz., +$.17/oz. on the day. Two mining producers closed the day as follows: Hecla Mining Company (HL) closed at $4.74,+7.48% and First Majestic Silver Corp. (AG) closed at $8.05, +9.23%. On July 12, Hecla Mining announced its preliminary production for the second quarter of 2022 highlighting the following: Silver production of 3.6 million ounces, an increase of 10% over the first quarter of 2022 due to record throughput at the Lucky Friday Mine, Gold production of 45,718 ounces, an increase of 10% over the first quarter, driven by better performance at the Casa Berardi mine, Zinc production increased 12% over the prior quarter & Lead production increased 23% due to increased production at Lucky Friday. On July 21, First Majestic Silver Corp. announced that total production in the second quarter of 2022 from the Company’s four producing operations, the San Dimas Silver/Gold Mine, the Jerritt Canyon Gold Mine, the Santa Elena Silver/Gold Mine and the La Encantada Silver Mine, reached 7.7 million silver equivalent (“AgEq”) ounces consisting of 2.8 million ounces of silver and 59,391 ounces of gold. The Company’s financial results for the second quarter of 2022 are scheduled to be released on Thursday, August 4, 2022.
Amgen (AMGN, $246.98, -.06%) announced that it has agreed to buyout ChemoCentryx (CCXI, $50.43, +109.17%) for $3.7B or for $52 per share in cash. Robert A. Bradway, chairman and chief executive officer at Amgen stated, “The acquisition of ChemoCentryx represents a compelling opportunity for Amgen to add to our decades-long leadership in inflammation and nephrology with TAVNEOS, a transformative, first-in-class treatment for ANCA-associated vasculitis. We are excited to join in the TAVNEOS launch and help many more patients with this serious and sometimes life-threatening disease for which there remains significant unmet medical need. We also look forward to welcoming the highly skilled team from ChemoCentryx that shares our passion for serving patients suffering from serious diseases.”
Shares of Global Blood Therapeutics Inc. (GBT), a biopharmaceutical company dedicated to the discovery, development and delivery of life-changing treatments that provide hope to underserved patient communities, starting with sickle cell disease (SCD), soared Thursday to close at $47.99, +41.44%. The giant move in GBT’s stock came after Bloomberg reported that GBT is “attracting takeover interest.”
Apple’s board of directors has declared a cash dividend of $.23 per share of the Company’s common stock. The dividend is payable on August 11, 2022 to shareholders of record as of the close of business on August 8, 2022.
Rather than conducting Part D of the Phase 1/2a clinical study, Atossa now plans to shift the development of AT-H201 to closely align with its oncology focus by continuing the development in patients with compromised lung-function due to the damaging effects of cancer treatment. For example, radiation treatment can lead to radiation induced lung injury, which is poorly treated with current therapies and is often irreversible. Furthermore, radiation damage can limit the overall success of lung cancer treatment leading to a reduction in efficacy and poor disease control. AT-H201 has pharmacological properties to potentially curtail excessive radiation-induced lung injury without compromising standard of care cancer therapy for cancer patients. AT-H201 is designed to prevent and reduce dose-limiting toxicities, and enable a more durable therapeutic tumor response for cancer patients receiving pulmonary radiation. Steven Quay, M.D., Ph.D., CEO and President of Atossa stated, “We are happy to have completed Parts A, B and C of the clinical trial and look forward to evaluating the results. With widespread availability of SARS-CoV-2 vaccines and other therapies now approved to treat COVID-19, we believe that altering the development pathways for AT-H201 in patients with compromised lung-function resulting from radiation may fill a compelling unmet medical need and create more value for our stockholders. Based on our work to date with AT-H201, we believe we can quickly initiate a clinical study in this setting and we plan to announce our next steps in the fourth quarter.”
On June 2, InMed Pharmaceuticals Inc. announced that it has entered into securities purchase agreements with a single healthcare-focused institutional investor for the issuance and sale of 4,079,256 of its common shares at a purchase price of $0.858 per share (or pre-funded warrant in lieu thereof) in a registered direct offering priced at-the-market under Nasdaq rules. In a concurrent private placement, InMed has also agreed to issue and sell to the investor 1,748,250 common shares (or pre-funded warrant in lieu thereto) at the same purchase price as in the registered direct offering. In addition, the Company has agreed to issue to the investor in the offerings unregistered preferred investment options (the “investment options”) to purchase up to an aggregate of 5,827,506 common shares. The aggregate gross proceeds to the Company of both offerings are expected to be approximately $5 million. The offerings are expected to close on or about June 6, 2022, subject to the satisfaction of customary closing conditions. The Company intends to use the net proceeds from the offerings to continue pipeline development, advance commercial activities and for general working capital purposes. H.C. Wainwright & Co. is acting as the exclusive placement agent for the offerings. The unregistered investment options to be issued in the offerings will be exercisable immediately upon issuance at an exercise price of $0.74 per share and will expire six and one-half years from the date of issuance. The Company also has agreed that certain existing warrants to purchase up to an aggregate of 4,480,771 common shares of the Company that were previously issued to the investor, with exercise prices ranging from $2.848 to $5.11 per share and expiration dates ranging from July 2, 2026 to November 16, 2026, will be amended effective upon the closing of the registered direct offering so that the amended warrants will have a reduced exercise price of $0.74 per share, will not be exercisable until six months following the closing of the registered direct offering and will expire seven years following the closing of the registered direct offering.
On May 5, InMed announced that its subsidiary, BayMedica, will be providing rare cannabinoids for use in Radicle Science, Inc.’s Radicle Energy rare cannabinoid study to assess the effects of delta-9 (“d-9”) dominant tetrahydrocannabivarin (“THCV”) on energy, focus/attention, appetite and weight/BMI. BayMedia will be supplying its highly pure d-9 dominant THCV, formulated into a proprietary lozenge manufactured by Trokie. This rare cannabinoid, consumer-based investigation will measure the effects of the Company’s d-9 dominant THCV in a randomized, blinded, placebo-controlled study in up to 900 adult participants aged 21 and older who reside in the United States. The study includes three dosing groups including a placebo group (no THCV), each delivered via Trokie’s proprietary lozenge technology. The study is set to begin participant recruitment in May and will run for a four week period starting in June with results expected during the summer. The study is part of Radicle Science’s large scale investigations into several rare cannabinoids involving up to 10,000 participants in total, the largest of its kind to date.
INmune Bio, Inc. (INMB) closed at $10.31, +2.59%. On August 3, INMB reported its financial results for the quarter ended June 30, 2022 and provides a business update. As of June 30, 2022, the Company had cash and cash equivalents of approximately $61.2 million. As of August 3, 2022, the Company had approximately 17.9 million common shares outstanding. RJ Tesi, M.D., CEO of INmune Bio stated, “In April, we announced the dosing of our first patient treated with XPro™1595 in the treatment of neuroinflammation as a cause of mild Alzheimer’s disease (AD) in Phase II clinical trial, AD02. The trial is a blinded, randomized, placebo-controlled multicenter study in Australia, in Canada and in the United States. Although the trial in the United States is currently on hold pending conclusion of the FDA’s manufacturing inquiry, we continue to enroll patients in Australia where the trial is proceeding as planned. Additionally, our plan to launch additional blinded, randomized, placebo-controlled Phase II trials in patients with mild cognitive impairment (MCI) and TRD will occur after the clinical hold is lifted. Our INKmune™ platform continues to make positive strides. We are actively expanding the INKmune program towards the treatment of solid tumors. INKmune primed NK cells have unique biologic characteristics that should make the therapy effective in solid tumors.”
On July 5, KDNY announced that the European Commission has granted orphan drug designation for BION-1301 for the treatment of primary IgA nephropathy (IgAN). The decision follows a positive opinion from the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMA). Orphan drug designation is granted to medicines that are intended to treat, prevent or diagnose a life-threatening or chronically debilitating rare disease with a prevalence in the European Union (EU) of fewer than five in 10,000 and with either no currently approved method of diagnosis, prevention or treatment or with significant benefit to those affected by the disease. Orphan designation in the EU provides sponsors with incentives including protocol assistance, 10 years of market exclusivity after approval and reductions in regulatory fees.
TOMORROW
Economic Reports
On Monday, the Final July IHS Markit Manufacturing PMI came in lower at 52.2%, while the July ISM Manufacturing Index came in slightly lower at 52.8%. The June Construction Spending report came in at -1.1%.
On Tuesday, the June JOLTS Job Openings report that ended lower at 10.698M.
On Wednesday, the Weekly MBA Mortgage Applications Index report came in at 1.2%, the Final July IHS Markit Services PMI came in at 47.3%, & the June Factory Orders came in at 2%, the July ISM Non-Manufacturing Index rose to 56.7% & the gasoline inventories report showed a 163K barrels build.
Investing & Inspiration
- “Wealth consists not in having great possessions, but in having few wants.” – Epictetus
- “If we open a quarrel between past and present, we shall find that we have lost the future.” – Winston Churchill
- “Hope is patience with the lamp lit.” – Tertullian
- “A single sunbeam is enough to drive away many shadows.” – Francis of Assisi
- “With the past, I have nothing to do; nor with the future. I live now.” – Ralph Waldo Emerson
- “Laziness may appear attractive, but work gives satisfaction.” – Anne Frank
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“I never think of the future – it comes soon enough.” – Albert Einstein
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Hope is but the dream of those who wake.” – Matthew Prior
- “The more sand that has escaped from the hourglass of our life, the clearer we should see through it.” – Jean Paul
- “Real knowledge is to know the extent of one’s ignorance.” – Confucius
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“Better keep yourself clean and bright; you are the window through which you must see the world.” – George Bernard Shaw
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“Nothing great in the world has ever been accomplished without passion.” – Georg Wilhelm Friedrich Hegel
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“History is a vast early warning system.” – Norman Cousins
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“We first make our habits, and then our habits make us.” – John Dryden
- “The traveler sees what he sees, the tourist sees what he has come to see.” – Gilbert K. Chesterton
- “Adventure is worthwhile.” – Aesop
- “We must build dikes of courage to hold back the flood of fear.” – Martin Luther King, Jr.
- “The return we reap from generous actions is not always evident.” – Francesco Guicciardini
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“Courage is knowing what not to fear.” – Plato
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“Science may never come up with a better office communication system than the coffee break.” – Earl Wilson
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“Progress was all right. Only it went on too long.” – James Thurber
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“If you would know strength and patience, welcome the company of trees.” – Hal Borland
- “We aim above the mark to hit the mark.” – Ralph Waldo Emerson
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“Hope is being able to see that there is light despite all of the darkness.” – Desmond Tutu
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“Our chief want is someone who will inspire us to be what we know we could be.” – Ralph Waldo Emerson
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“Patience is a virtue, and I’m learning patience. It’s a tough lesson.” – Elon Musk
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“Great things are done when men and mountains meet.” – William Blake
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“The man who has no imagination has no wings.” – Muhammad Ali
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“Formula for success: rise early, work hard, strike oil.” – J. Paul Getty
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“Action is the foundational key to all success.” – Pablo Picasso
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“Hope is like the sun, which, as we journey toward it, casts the shadow of our burden behind us.” – Samuel Smiles
“The backbone of surprise is fusing speed with secrecy.” – Carl von Clausewitz
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“There are no shortcuts in evolution.” – Louis D. Brandeis
- “I am fascinated by what is beautiful, strong, healthy, what is living. I seek harmony.” – Leni Riefenstahl
- “If one advances confidently in the direction of his dreams, and endeavors to live the life which he has imagined, he will meet with a success unexpected in common hours.” – Henry David Thoreau
- “Waste no more time arguing about what a good man should be. Be one.” – Marcus Aurelius
- “It is during our darkest moments that we must focus to see the light.” – Aristotle Onassis
- “Courage is fear holding on a minute longer.” – George S. Patton
- “You must be the change you wish to see in the world.” – Mahatma Gandhi
- “Don’t judge each day by the harvest you reap but by the seeds that you plant.” – Robert Louis Stevenson
- “It is in the character of very few men to honor without envy a friend who has prospered.” – Aeschylus
- “Life is a series of natural and spontaneous changes. Don’t resist them – that only creates sorrow. Let reality be reality. Let things flow naturally forward in whatever way they like.” – Lao Tzu
- “The more you praise and celebrate your life, the more there is in life to celebrate.” – Oprah Winfrey
- “Anything simple always interests me.” – David Hockney
- “He who angers you conquers you.” – Elizabeth Kenny
- “Concision in style, precision in thought, decision in life.” – Victor Hugo
- “The secret of genius is to carry the spirit of the child into old age, which means never losing your enthusiasm.” – Aldous Huxley
- “View health as an investment, not an expense.” – John Quelch
- “The most effective way to do it, is to do it.” – Amelia Earhart
- “Man needs his difficulties because they are necessary to enjoy success.” – A. P. J. Abdul Kalam
- “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha
- “Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
- “You must do the things you think you cannot do.”- Eleanor Roosevelt
- “Success is dependent on effort.” – Sophocles
- “Nobody who ever gave his best regretted it.” – George Halas
- “Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
- “And when I breathed, my breath was lightning.” – Black Elk
- “Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
- “You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
- “If you want a guarantee, buy a toaster.” – Clint Eastwood
- “We are an impossibility in an impossible universe.” – Ray Bradbury
- “If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
- “I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
- “Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
- “It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
- “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
- Surprise is the greatest gift which life can grant us.” – Boris Pasternak
- “Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran
- “Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
- “All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
- “There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” – Colin Powell
- “There is more to life than increasing its speed.” – Mahatma Gandhi
- “Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
- “Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
- “Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
- “In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
- “Life is too short for long-term grudges.” – Elon Musk
- “There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
- “Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
- “The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
- “Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
- “Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
- “But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
- “Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
- “Let there be work, bread, water and salt for all.” – Nelson Mandela
- “The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
- “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
- “I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
- “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
- “If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
- “Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
- “Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
- “Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
- “You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
- “Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
- “Delete the negative; accentuate the positive!” – Donna Karan
- “It’s crazy how fast time flies and how things progress.” – Nathan Chen
- “The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
- “Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
- “Everything has beauty, but not everyone sees it.” – Confucius
- “A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
- “Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
- “A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
- “The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
- “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
- “I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
- “Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
- “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
- “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
- “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
- “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
- “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
- “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
- “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
- “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
- “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
- “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
- “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
- “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
- “There is little that can withstand a man who can conquer himself.” – Louis XIV
- “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
- “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
- “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
- “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese
- “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
- “Never do anything against conscience even if the state demands it.”– Albert Einstein
- “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
- “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
- “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
- “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
- “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
- “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
- “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
- “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
- “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch
- “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
- “The secret of getting ahead is getting started.” – Mark Twain
- “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe
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