‘Uncle Jerry’ Resets Stock Market This Week With His ‘Very Premature’ Rhetoric – $AG $FSLR $JPM $NVDA $SHIP Rise!
Happy Saturday All!
I hope all is well and that you are having a wonderful weekend. As for the markets this week, investors overall realized a reversal of sorts after a the nice and recent rebound that left many quite disturbed. The concern came as the Fed moved up interest rates once again by .75 basis points as was expected, however, then Fed Chair ‘Uncle Jerry’ Powell went on a war path of sorts during his speech and questions session. He indeed made sure that everyone understood that it was his show and that his program confirmed that the talk of beating inflation was indeed ‘very premature’ and that rates are set to move much higher. The Fed now seems it is now moving interest rates towards a peak fund rate between 5-5.3% by March 2023. In turn, the markets again legged lower overall despite a nice bounce on Friday that came as the job data report revealed that the unemployment rate rose to 3.7%.
In turn, the S&P 500 closed at 3,771 down 3.3% for the week, and is now down 20.9% YTD. Adding to the pressure on the S&P was the 6.82% weighting of Apple (AAPL) shares, which closed at $138.38 down 11.15% over the last 5-days experiencing one its worst performing performing week’s that I can remember, at least in recent times. The Dow 30 closed lower at 32,403 and down 1.4% for the week and is now down on 10.8% YTD. The Nasdaq closed at 10,475 chunking down a meaty 5.6% weekly & is now down a whopping 33% YTD. Curiously, the CBOE Volatility Index (^VIX) closed at $24.55, -4.66% over the last 5-days and remains up +42.57% YTD. The small caps on the Russell 2000 also fell this week and closed at 1,799.87 down 2.55% for the week & is now down 19.84% YTD. The MicroCaps reversed tracks as well as the iShares Micro-Cap ETF (IWC) closed at $110.55, 2.12% over the last 5-days and is now down 20.88% YTD.
In the US, the yield curve ended the week with the 2-yr note yield moving up 25 basis points at 4.69% & the 10-yr note yield moved up to end at 4.164%. Oil prices closed on Friday to end at $92.53/bbl, up 5.3% this week, despite President Biden’s move to deplete our reserves in his battle with OPEC+, Russia, etc. The US dollar ticked up this week as it moved up from last Friday’s close of $110.67 to $110.79.
THE MAC REPORTS
On Monday, the October Chicago PMI clocked in lower at 45.
On Tuesday, the U.S. macroeconomic schedule produced the October ISM Manufacturing Index report that confirmed a fall to 50.2% further signaling a slowdown and closing just above the expansion line. However, the total construction spending report showed a .2% M/M rise in September & the total private construction report also showed .4% M/M rise, but total public construction spending moved lower by .4%. Interestingly, the total construction spending report also confirmed that it was up 10.9% Y/Y. Lastly, the JOLTS Job openings report came in higher and totaled 10.717M in September.
On Thursday, the Weekly Initial Claims came in lower at 217K , while weekly Continuing Claims and in a little higher at 1.485M. The September Trade Balance report casein at -$73.3B. The Q3 Preliminary Productivity report came in lower at .3%. The October IHS Markit Services Final PMI report came in higher at 47.8 & the September Factory Orders came in at .35.
On Friday, nonfarm-payrolls jobs report for the month of October confirmed that jobs rose by 261k above expectations, while the unemployment rate moved by .2% to 3.7% in concert with the labor-force participation ticking down by .1% to 62.2%. The wage gains were up 4.7% YOY as was expected, but monthly wage gains jumped by .40% exceeding expectations.
BIOTECH AND HEALTHCARE
Biotech stocks moved overall lower this week and the smaller you were in general the more that was the case. Overall the Nasdaq Biotechnology ETF (IBB) pulled back and closed at $128.34, -1.03% over the last 5-days, & is down -15.91% YTD. The NYSE ARCA Biotech Index (^BTK) closed at 4,930.50, -.19% over the last 5-days and is now down -10.65% YTD. The SPDR S&P Biotech ETF (XBI) closed at $79.96, -4.54% over the last 5-days & is now down 28.58% YTD. The 52-week range is is now $61.78-$133.33.
The iShares U.S. Healthcare ETF (IYH) closed at $271.52, -1.79% over the last 5-days.
EV, TECH, CONSUMER, FINANCIALS
Apple (AAPL) closed at $138.38, -11.15% over the last 5-days. Apple represents a 6.82% weighting in the S&P 500. Last week, Apple reported its fiscal Q4 earnings confirming record revenue, but missed Wall Street’s expectations with regard to iPhone & their services segment.
EV giant Tesla (TSLA) closed at $207.47, -9.21% over the last 5-days.
Shares of JPMorgan (JPM) closed at $130.68, +3.65% over the last 5-days. On November 3, Chase Home Lending announced the expansion of its $5,000 Homebuyer Grant program to nearly 5,000 Hispanic and Latino communities in 20 markets across the country. The grant can be applied toward two of the biggest barriers to homeownership—the upfront cash needed for a down payment and closing costs..
Amazon.com, Inc. (NASDAQ: AMZN) $90.98, -12.02% over the last 5-days. On Thursday, November 3, Amazon and the U.S. Agency for International Development (USAID) announced that they are launching a public-private partnership to address the gender inequities that exist for women in the climate finance ecosystem and support female entrepreneurs with the resources they need to accelerate climate change innovations. Amazon will commit a total of $53 million to help accelerate women’s climate solutions, including $3 million toward the USAID partnership and $50 million for Amazon to invest directly in climate tech companies run by women.
Shares of Microsoft Corp. (MSFT) closed at $221.39, -6.14% over the last 5-days. On Nov. 3, Raytheon Technologies announced that it is deepening its collaboration with Microsoft to equip the aerospace and defense company’s employees with cloud-based tools, technologies, and platforms to enhance collaboration, optimize operations and unlock intelligent insights that drive greater value for customers. The effort includes co-development of capabilities, as well as Raytheon Technologies’ use of existing or modified versions of popular Microsoft solutions such as Microsoft Teams. It is part of the company’s strategy to optimize operations and give employees access to standardized digital tools globally. Last week, Microsoft, reported its fiscal Q1 results beating expectations, but offered lower guidance. Microsoft highlighted that its cloud-computing services provided strength, but then its Azure infrastructure business increased at a slower than expected rate.
Shares of Salesforce, Inc. (CRM) closed at $139.77, -14.26% over the last five days. Activist hedge fund Starboard Value founder Jeff Smith recently revealed buying a stake in the enterprise software maker. Salesforce has been recognized by Gartner as a Leader in the 2022 Magic Quadrant for Sales Force Automation Platforms. It is the 16th consecutive year that Salesforce has received this recognition. On September 21, Salesforce announced the appointment of Robin Washington as Lead Independent Director of the Company’s Board of Directors, effective September 15, 2022. Washington, who also chairs the Board’s Audit Committee, succeeds Sanford Robertson, who will continue to serve as a Director and Chair of the Nominating and Corporate Governance Committee.
Shares of NVIDIA (NVDA), a pioneer in accelerated computing, closed at $141.56, +2.33% over the last 5-days. NVIDIA will host a conference call on Wednesday, November 16, at 2 p.m. PT (5 p.m. ET) to discuss its financial results for the third quarter of fiscal year 2023, which ended October 30, 2022. The call will be webcast live (in listen-only mode) on investor.nvidia.com. The company’s prepared remarks will be followed by a question-and-answer session, which will be limited to questions from financial analysts and institutional investors. On Oct. 18, Oracle and NVIDIA announced a multi-year partnership to help customers solve business challenges with accelerated computing and AI. The collaboration aims to bring the full NVIDIA accelerated computing stack — from GPUs to systems to software — to Oracle Cloud Infrastructure (OCI).
Cathie Wood’s ARK Innovation ETF (ARKK) closed at $35.22, -9.44% over the last 5-days.
The Technology Select Sector SPDR Fund (XLK) closed at $120.99, -6.63% over the last 5-days.
Walt Disney Company (DIS) closed at $99.58, -6.01% over the last 5-days. On October 25, Reuters reported that Disney’s streaming service Disney+ stated that it would exclusively stream one of BBC’s highly revered shows, “Doctor Who”, to audiences outside the U.K. and Ireland.
The Walt Disney Company will discuss fiscal full year and fourth quarter 2022 financial results via a live audio webcast beginning at 4:30 p.m. ET / 1:30 p.m. PT on Tuesday, November 8, 2022. Results will be released after the close of regular trading on November 8, 2022. To listen to the webcast, please visit www.disney.com/investors.
Shares of McDonald’s (MCD) closed at $274.62, +.04% over the last 5-days. On October 27, McDonald’s Corporation announced results for the third quarter ended September 30, 2022 and highlighted the following: 1) Global comparable sales increased nearly 10%, with growth across all segments, 2) U.S. comparable sales increased more than 6% for the quarter, marking the ninth consecutive quarter of comparable sales growth for the segment, & 3) Digital Systemwide sales* in our top six markets were nearly $7 billion for the quarter, representing over a third of total Systemwide sales in those markets.
GOLD & SILVER
Gold prices closed at $1,685/oz., +$36/oz. & silver prices closed at $20.88/oz., +$1.63/oz. for the week.
Hecla Mining (HL) closed at $4.76, +1.93% over the last 5-days & First Majestic (AG) closed at $8.96, +6.67% over the last 5-days.
On Nov. 1, First Majestic Silver Corp. announced positive drilling results from its ongoing exploration program at the Jerritt Canyon Gold Mine located in Elko County, Nevada. The 2022 drilling campaign at Jerritt Canyon consists of short-term focused underground core drilling testing extensions of known ore controls near active mining; mid-term focused drilling planned to validate/test the presence of mineralized volumes near historic workings; and long-term focused drilling aiming to make new gold discoveries in the district.
On Sept. 7, Hecla Mining Company and Alexco Resource Corp. (NYSE American: AXU; TSX:AXU) announced that the Alexco acquisition has been completed.
MEMES CENTRAL
AMC Entertainment (AMC) closed at $5.65, -13.21% over the last 5-days. AMC is set to report its earnings on Nov. 8. Reportedly, AMC’s LA-based theaters have added “Laser” and can can expect improved picture contrast, maximum picture brightness, & apparently a more vivid color on-screen. On October 24, Fathom Events, a recognized leader in the entertainment industry as one of the top distributors of content to movie theaters in North America that is owned by AMC Entertainment, Cinemark Holdings, Inc. (NYSE: CNK); and Regal, a subsidiary of the Cineworld Group (LSE: CINE.L), announced that “The Dark Crystal” is returning to the big screen in celebration of its 40th Anniversary. The movie is a masterful, live-action fantasy starring some of the most imaginative creatures ever put on film. Do you remember it?
GameStop (GME) closed at $26.51, -5.89% over the last 5-days as the shorts won this week. Note that approx. 20% of GME’s outstanding shares are sold short landing it with a short interest ratio of 7.6. On Sept 7th, GameStop released financial results for the second quarter ended July 30, 2022. Net sales were $1.136 billion for the quarter, compared to $1.183 billion in the prior year’s second quarter. Sales attributable to collectibles, which is a segment the Company intends to grow over the long-term, were $223.2 million for the quarter, compared to $177.2 million in the prior year’s second quarter. Selling, general and administrative expenses were $387.5 million for the quarter, representing a sequential decline of 14.3% from the first quarter of 2022 and reflecting, in part, the Company’s focus on right-sizing costs following a period of significant investment in long-term initiatives. After the close today, September 7, GameStop Corp. also announced that it has entered into a partnership with FTX US (“FTX”). The partnership is intended to introduce more GameStop customers to FTX’s community and its marketplaces for digital assets. In addition to collaborating with FTX on new ecommerce and online marketing initiatives, GameStop will begin carrying FTX gift cards in select stores. During the term of the partnership, GameStop will be FTX’s preferred retail partner in the United States. The financial terms of the partnership are not being disclosed.
Seanergy Maritime Holdings Corp. (NASDAQ: SHIP) closed at $.4783, +3.98% over the last 5-days. On Oct. 13, Seanergy announced the closing of its previously announced $28.0 million term loan secured by two 2010-built Capesize vessels, M/V Fellowship and M/V Premiership, with a prominent European financing institution. The facility has refinanced an existing facility at an interest rate is 2.50% plus SOFR per annum compared to 3.50% plus LIBOR in the previous facility secured by the same vessels. The $28 million principal will amortize over a five-year term through quarterly instalments averaging approximately $1.2 million and a $4.1 million final balloon payment at maturity.
CRYPTO & BITCOIN
Bitcoin (BTC) closed nicely above the 20k mark at $21,100.07, +2.95% over the last 5-days at the time this report was prepared.
ENERGY
The Energy Select Sector SPDR Fund or ETF (XLE) closed at $91.42, +2.43% over the last 5-days. Chevron (CVX) closed at $183.42, +1.91% over the last 5-days. Warren Buffet’s pick in the space, Occidental Petroleum (OXY) closed at $72.27, +1.99% over the last 5-days.
Shares of First Solar, Inc. FSLR) rose to $153.62, +15.79% over the last 5-days. On October, 27 FSLR announced that it plans to invest approximately $270 million in a dedicated research and development (R&D) innovation center in Perrysburg, Ohio. The new facility is believed to be the first of its scale in the United States and is expected to accelerate American leadership in the development and production of advanced thin film photovoltaics (PV).
Oil prices closed on Friday to end at $92.53/bbl, up 5.3% this week.
NEXT WEEK
A full set of 5 trading days will be back in play next week… Expect volatility.
VP WATCHLIST UPDATES
Please review our complete VP Watchlist that includes Apple (AAPL), Disney (DIS), Tesla (TSLA) & a select group of emerging names. The pages will allow you to learn more and keep up with these companies daily.
For now, please see the summaries from the VP Watchlist below:
- Shares of Natural-Killer cell (NKcell) focused biopharmaceutical firm Fate Therapeutics (FATE) closed at $19.84, -8.99% over the last 5-days.
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November 3, Fate reported business highlights and financial results for the third quarter ended September 30, 2022 with Cash, cash equivalents and investments as of September 30, 2022 were $519.1 million. Scott Wolchko, President and Chief Executive Officer of Fate Therapeutics stated, “We are very pleased with the positive feedback from the FDA under our FT516 RMAT designation in support of our iPSC product platform and potential registrational pathways for the treatment of relapsed / refractory aggressive lymphomas, including for patients who have previously failed CD19-targeted CAR T-cell therapy, and we look forward to engaging the FDA in the fourth quarter to discuss CMC topics in support of pivotal trial readiness. We are also excited to present interim Phase 1 clinical data at the upcoming SITC and ASH conferences, including for our iPSC-derived CAR NK cell programs FT576 in multiple myeloma and FT536 in solid tumors as well as for the first-ever iPSC-derived CAR T-cell program FT819 in B-cell lymphoma. Finally, under our collaboration with Janssen, we are pleased to announce our first IND candidate FT555, a multiplexed-engineered, iPSC-derived CAR NK cell targeting GPRC5D for multiple myeloma, and that Janssen has also exercised its commercial option to an additional product candidate targeting an undisclosed hematologic malignancy antigen.”
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- Shares of Atossa Therapeutics, Inc. (Nasdaq: ATOS), a clinical-stage biopharmaceutical company seeking to discover and develop innovative medicines in areas of significant unmet medical need in oncology, with a current focus on breast cancer and radiation-induced lung injury, closed at $.8558.
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On November 1, Atossa announced that it is investing in privately-held developer of CAR-T therapies, Dynamic Cell Therapies, Inc. (DCT), a venture capital backed company that is based in Boston, MA. DCT is in the pre-clinical phase of developing controllable CAR-T cells to address difficult-to-treat cancers. Its platform technology of dynamic control of engineered T-cells is designed to improve the safety, efficacy, and durability of CAR-T cell therapies. This system should find initial applications in hematological cancers, with future approaches in solid tumors and autoimmune diseases. The company’s platform technology uncouples tumor targeting from CAR-T cell activation. Each CAR-T cell recognizes an inert small molecule. This small molecule is conjugated to a tumor-specific antibody. By dosing a small molecule-antibody conjugate, the physician could dynamically control CAR-T cell activity and potentially minimize the risk of life-threatening side effects. Increasing the dose of the small molecule-antibody conjugate should strengthen the immune attack against tumor cells. In addition, the same small molecule can be coupled to different tumor targeting antibodies, allowing the physician to maximize on-target on-tumor efficacy and reduce off-tumor toxicities. To learn more, please visit www.dynamiccelltherapies.com. Steven Quay, M.D., Ph.D., Atossa’s CEO, Chairman and President stated, “This investment in DCT is an important step in pursuing our strategy to develop CAR-T therapies or adjacent opportunities within the immuno-oncology space. We believe that as an active investor in the development of DCT we will be well positioned to evaluate future opportunities while strategically managing our cash position.” Atossa will acquire shares equal to 19.99% of the outstanding capital stock of DCT as of today for a cash payment of $2 million (in addition to $3 million previously paid to DCT). The transaction is expected to close in the fourth quarter.
- On October 25, Atossa announced that it has retained Richard Graydon, M.D., Ph.D. as interim chief medical officer. Dr. Graydon will devote all of his professional time to the Atossa clinical programs. Prior to joining Atossa, Dr. Graydon served as Senior Director of Clinical Development at Johnson and Johnson (JNJ) where he was responsible for leading compound development and clinical trial programs for Janssen Pharmaceuticals. At Janssen, he oversaw the early to late-stage development and the 2022 approval of BCMA-directed CAR T-Cell therapy (cilta-cel) for Multiple Myeloma, as well as daratumumab, imbruvica, siltuximab and other compounds for solid tumor and hematological malignancies. Previously, he held the role of Director of Clinical Development at Daiichi Sankyo, Inc., where he led the early and late-stage development of the small molecule targeted therapy quizartinib for FLT3-positive Acute Myeloid Leukemia. Additionally, he led the early-stage development of the MDM2 inhibitor milademetan in hematological malignancies and liposarcomas. Dr. Graydon spent time in clinical practice following completion of his specialty training in hematology and oncology at Harvard Massachusetts General Hospital. He earned his M.D. and Ph.D. at Stanford University, and undergraduate degree in Chemical Engineering at Cornell University. Dr. Graydon is the author of The Genetic Risks of Cancer: The Effects of DNA, Genomics and Inheritance on Aging and Survival.
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On Oct. 24, Atossa announced that the U.S. Food and Drug Administration (FDA) has lifted the clinical hold and authorized initiation of its Phase 2 neoadjuvant clinical study of (Z)-endoxifen in premenopausal women with early-stage estrogen receptor positive (ER+) and human epidermal growth factor receptor 2 negative (HER2-) breast cancer. This is the first study of Atossa’s proprietary (Z)-endoxifen in the United States. At this time, Atossa also announced that it is discontinuing its COVID-19 program (AT-301) so that it can refocus resources on this critical study in breast cancer. “Continuing the development of our proprietary (Z)-endoxifen here in the United States has been a key goal which builds on the recent issuance of a U.S. patent for our proprietary (Z)-endoxifen and results from our Phase 2 “window-of-opportunity” study in Australia,” commented Steven Quay, M.D., Ph.D., Atossa’s CEO, Chairman and President. “We are excited to have engaged Dr. Matthew Goetz, the Erivan K. Haub Family Professor of Cancer Research Honoring Richard F. Emslander, M.D. at Mayo Clinic and Director of the Mayo Clinic Breast Cancer SPORE, as the lead principal investigator for this multi-center study. We look forward to opening the study in the fourth quarter.”
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On Aug. 25th, Atossa’s CEO, Dr. Steven Quay, M.D., Ph.D., and Kyle Guse, GC & CFO presented at Tribe Public’s Webinar Presentation and Q&A Event. During this complimentary event, Atossa management spoke of new opportunities for its inhalation therapy, AT-H201, to potentially treat lung injury caused by cancer treatment and were available for a Q&A session focused on Atossa’s research programs and future development. To watch the event video titled “The Important Role For Inhalation Therapy In Oncology” please visit the Tribe Public YouTube Channel.
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On July 28, Jason McCarthy Ph.D., a biotech analyst at the Maxim Group, put out a note reconfirming his BUY rating and a $4 target price on Atossa.
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- Shares INVO Bioscience (NASDAQ: INVO), a medical device company focused on creating alternative treatments for patients diagnosed with infertility and developers of INVOcell®, the world’s only in vivo Intravaginal Culture System, closed at $1.1178/share, but have traded up to $1.23, +10.04% in the aftermarket on Friday. The 52-wk range is $.63 – $4.28.
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- On Nov. 1, INVO announced a successful showcasing of INVOcell at last week’s 2022 Scientific Congress & Expo of the American Society for Reproductive Medicine (ASRM) held on October 22-26, 2022 in Anaheim, California. INVO highlighted the following: 1) The multi-billion-dollar global fertility market is predicted to reach approximately US$47.9 billion by 2030, yet remains severely underserved with many patients (upwards of 90% by many estimates) unable to access affordable treatment, 2) The INVOcell solution provides an advanced, effective and affordable infertility treatment to help increase access to care, & 3) INVO Is commercially advancing INVOcell through the opening of INVO Centers, opportunistically now pursuing acquisitions of established fertility (IVF) clinics in the U.S., and continuing to offer the technology to existing fertility practices. Steve Shum, CEO of INVO Bioscience stated, “INVO’s cumulative progress over the past two years, on both the commercial front as well as additional real world patient outcomes data, allowed us to further highlight our innovative INVOcell solution at last week’s ASRM conference. It was clear at this year’s annual conference that INVOcell’s presence in the marketplace is growing, and our expanded commercial approach is attractive. Our business development team engaged in a number of productive discussions with interested parties at the conference revolving around our commercial efforts toward providing INVOcell to existing clinics, opening our own INVO Centers, and now selectively acquiring existing fertility practices. We believe the strategy to acquire established fertility clinics in the U.S. complements our existing INVO Center strategy and will allow us to accelerate our growth plans and help expand the use of INVOcell. Potential acquisitions of established profitable fertility clinics in the U.S. represents a logical extension of our strategy. We believe the ASRM conference provided a great opportunity to further communicate our overall progress and technology achievements as well as our unique commercial approach toward helping to democratize fertility care.”
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- On Oct. 21, INVO Bioscience announced the publication of a review discussing existing literature and current use of intravaginal culture (IVC) as an option for patients seeking fertility therapies. The review, titled “Intravaginal embryo culture: a successful alternative to standard IVF that may improve access to care,” by Dr. Amber R. Cooper was published in the Current Opinion in Obstetrics and Gynecology. Findings included that Intravaginal culture (IVC) of embryos is a successful and well-tolerated option for many patients & IVC has similar outcomes when compared to standard IVF with or without ICSI. Findings included: Intravaginal culture (IVC) of embryos is a successful and well-tolerated option for many patients & IVC has similar outcomes when compared to standard IVF with or without ICSI. A copy of the publication is available at:Intravaginal embryo culture: a successful alternative to standard IVF that may improve access to care.
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- On Sept 22, INVO announced that Dr. Sue Ellen Carpenter of Bloom Fertility, the Company’s Atlanta-based INVO Center, was named a recipient of the Castle Connolly Top Doctor Award for 2023. Castle Connolly Top Doctor recipients are nominated by fellow physicians and other healthcare leaders around the country identifying doctors that embody excellence in clinical care as well as interpersonal skills such as listening and communicating, demonstrating empathy and instilling trust and confidence in patients. Dr. Carpenter has been a recipient of the merit-based Castle Connolly Top Doctor Award since 2018.
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- On Aug. 25th, INVO Bioscience announced that Advanced Reproductive Centre, Hospital Canselor Tuanku Muhriz (HCTM), formally known as Hospital Universiti Kebangsaan Malaysia (HUKM), based in Kuala Lumpur, Malaysia, is making IVC available for their patients. The move follows the successful completion of the first IVC case in the country recently with data presented at the Obstetrical and Gynecological Society of Malaysia (“OGSM”) where it was awarded a prize as a new and innovative fertility treatment. A signing ceremony announcing the launch of IVC was witnessed by the Minister of Science and Innovation and Deputy Secretary General. HCTM, one of the five university hospitals in Malaysia, is currently the highest volume fertility center in the country. Steve Shum, CEO of INVO Bioscience, commented, “We are excited that INVOcell will officially be commercialized at HCTM in Kuala Lumpur following the successful presentation of data at OGSM and government support by the Minister of Science and Innovation and Deputy Secretary General. HCTM will start offering IVC both in their public and private sectors with an expectation to complete a number of cycles by the end of 2022. We are also working with partners in Malaysia to open up an INVO Centers in their existing practice as we strive to bring our innovative advanced fertility treatment to the people of Malaysia.”
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- ***INSIDER BUYING ALERT***– On Friday June 3, after the close, a number of Form 4’s were filed c. at www.sec.gov confirming that the CEO, COO, CFO and 5 members of the board of directors purchased shares at $.95/share on June 1, 2022. Here’s the link to view all of the share purchases.
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- On Nov. 3, Chinook announced two posters and three informational posters being presented today at ASN Kidney Week 2022 being held virtually and live in Orlando, Florida. “The updated interim data from the IgAN patient cohort of the atrasentan phase 2 AFFINITY basket trial continue to demonstrate highly consistent and clinically meaningful proteinuria reductions in patients with IgAN already on a maximally tolerated and stable dose of a RAS inhibitor,” said Eric Dobmeier, president and chief executive officer of Chinook Therapeutics. “We are encouraged by these results, and look forward to reporting topline proteinuria data from our ongoing phase 3 ALIGN trial in 2023.”
- Borqs Technologies, Inc. (Nasdaq: BRQS, $.6250), a global provider of 5G wireless solutions, Internet of Things (IoT) solutions, and innovative clean energy, recently provided the following updates on the Company.
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- On Oct. 21, Borqs announced its financial results for the six months ended June 30, 2022 and highlighted that Revenues for the first half 2022 reached $30.1 million, 141% Year-Over-Year (YOY) growth, thew Revenue forecast for 2022 is $50-55 million, YOY growth of over 69%, & their backlog currently stands at $50 million for Holu Hou Energy, LLC (HHE), a majority-owned solar & energy storage system subsidiary.
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- On October 12, Borqs announced that the Company has forayed into two/three-wheelers automotive space by developing the Telematics Control Unit (TCU) and has successfully demonstrated the newly developed TCU in India Mobile Congress held in New Delhi from October 1 to 4. The newly developed TCU is installed on a two-wheeler and connected to the internet via the cellular network. Indian electric vehicle market was valued at USD 1,434.04 billion in 2021, and it is expected to reach USD 15,397.19 billion by 2027. India’s automotive sector is dominated by two-wheelers (scooters, motorbikes) and three-wheelers (autos and rickshaws) that play a significant role in last-mile mobility in the country. The total sales of electric two-wheelers, including high-speed and low-speed, in the 12-month period (January-December) in 2021 increased by 132% over the corresponding year 2020.
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- On Sept 20, Borqs announced its solar energy storage subsidiary, Holu Hou Energy LLC (HHE), a company that offers state-of-the-art renewable energy and energy storage systems to the Single-Family Residential, Multi-Dwelling Unit Residential and Commercial building markets, has signed a power purchase agreement (PPA) with Kapolei Diversified Properties, LLC to deliver energy to Luhauola, a new mixed-use development in Kapolei, on the island of Oahu, Hawaii. The property includes 10,000 square feet of commercial space, plus outdoor dining for local food establishments. The residential portion of the property includes 29 workforce housing rental apartments. U.S. Energy Information Administration data shows oil generated about two-thirds of Hawaii’s electricity in 2021. That makes Hawaii the most petroleum-dependent state.
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Borqs Technologies’ subsidiary, Holu Hou Energy (HHE), has rolled out its next generation HoluPower xP energy storage system. The HoluPower xP building on the leading attributes of the HoluPower series product, specifically delivers:
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A much safer lithium ion battery chemistry, having greater inherent resiliency against overtemperature and overcharging than some major brands that use less stable, more flammable and higher toxicity chemistries.
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More system power – enough power to enable homes to operate their appliances during an outage the same way they would if they had utility power.
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Greater system modularity – each system can support four strings of PV and up to four 8.2kWh battery modules. Multiple systems can be connected together in a sharing link for even greater capacity.
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Higher power for each battery module, a very important attribute for locations where battery subsidies and bonus programs exist.
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Energy control through the HHE Modular Energy Control platform.
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Integrated home load control so both renewable energy supply and load/usage can be scheduled or optimized real time with one another.
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Standard wired internet connection, with optional WiFi or cellular communications.
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Better system conversion efficiency compared to “AC Battery” systems, like those from Tesla.
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Faster installation times with an almost 50% reduction in wiring terminations.
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The industry’s only single-family Residential energy storage system economically viable for unlocking the Multi-Dwelling Unit Residential market.
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- To view a video clip of a recently completed HHE Multi-Unit Residential project go to: https://www.youtube.com/watch?v=kakbynGM-fQ
Shares of InMed Pharmaceuticals Inc. (INM), a leader in the research, development and manufacturing of rare cannabinoids, closed at $2.50.
- On Oct. 26, InMed announced that it is supporting initiatives to raise awareness of epidermolysis bullosa, a group of rare genetic connective tissue disorders. Epidermolysis Bullosa Global Awareness Week is October 25-31, 2022.
- Alexandra Mancini, Senior Vice President of Clinical and Regulatory Affairs for InMed commented, “In severe cases of epidermolysis bullosa, or EB, the very fragile skin tears easily and forms painful blisters and open wounds that do not heal quickly. EB is a very important but rare disease that does not get the attention it deserves. EB Awareness Week is an opportunity for the community to come together to raise awareness about epidermolysis bullosa to foster the necessary research and resources to work towards better treatments and, eventually, a cure to improve the lives of those with EB. InMed has undertaken a Phase 2 study in patients with EB in the hope that its cannabinol cream will provide important symptom benefit.”
Thanks again for your attention this week. Please continue to share your thoughts, questions, & ideas as we move forward.
In the meantime, please enjoy the balance of the weekly newsletter’s videos, quotes, updates and let’s find ways to crush it again this year!
Investing & Inspiration
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“I want to put a ding in the universe.” – Steve Jobs
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“Research is creating new knowledge.” – Neil Armstrong
- “The reward for work well done is the opportunity to do more.” – Jonas Salk
- “Man is a creative retrospection of nature upon itself.” – Karl Wilhelm Friedrich Schlegel
- “There’s something about taking a plow and breaking new ground. It gives you energy.” – Ken Kesey
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“Success seems to be largely a matter of hanging on after others have let go.” – William Feather
- “The essential conditions of everything you do must be choice, love, passion.” – Nadia Boulanger
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“More business is lost every year through neglect than through any other cause.” – Rose Kennedy
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“Give me a lever long enough and a fulcrum on which to place it, and I shall move the world.” – Archimedes
- “A person who won’t read has no advantage over one who can’t read.” – Mark Twain
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“The best way out is always through.” – Robert Frost
- “Start by doing what’s necessary; then do what’s possible; and suddenly you are doing the impossible.” – Francis of Assisi
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“Without labor nothing prospers.” – Sophocles
- “Intellectuals solve problems, geniuses prevent them.” – Albert Einstein
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“This is the precept by which I have lived: Prepare for the worst; expect the best; and take what comes.” – Hannah Arendt
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“The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller
- “He who is brave is free.” – Lucius Annaeus Seneca
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“When something is important enough, you do it even if the odds are not in your favor.” – Elon Musk
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“I choose a block of marble and chop off whatever I don’t need.” – Auguste Rodin
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“Hope is the only bee that makes honey without flowers.” – Robert Green Ingersoll
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“He who knows that enough is enough will always have enough.” – Lao Tzu
- “Plans to protect air and water, wilderness and wildlife are in fact plans to protect man.” – Stewart Udall
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“In order to carry a positive action we must develop here a positive vision.” – Dalai Lama
- “A hero is someone who understands the responsibility that comes with his freedom.” – Bob Dylan
- “Inflation destroys savings, impedes planning, and discourages investment. That means less productivity and a lower standard of living.” – Kevin Brady
- “If we give something positive to others, it will return to us. If we give negative, that negativity will be returned.” – Allu Arjun
- “A good plan violently executed now is better than a perfect plan executed next week.” ~ George S. Patton
- “You must do the things you think you cannot do.”- Eleanor Roosevelt
- “Success is dependent on effort.” – Sophocles
- “Nobody who ever gave his best regretted it.” – George Halas
- “Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
- “And when I breathed, my breath was lightning.” – Black Elk
- “Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
- “You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
- “If you want a guarantee, buy a toaster.” – Clint Eastwood
- “We are an impossibility in an impossible universe.” – Ray Bradbury
- “If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
- “I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
- “Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
- “It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
- “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
- Surprise is the greatest gift which life can grant us.” – Boris Pasternak
- “Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran
- “Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
- “All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
- “There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” – Colin Powell
- “There is more to life than increasing its speed.” – Mahatma Gandhi
- “Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
- “Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
- “Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
- “In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
- “Life is too short for long-term grudges.” – Elon Musk
- “There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
- “Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
- “The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
- “Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
- “Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
- “But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
- “Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
- “Let there be work, bread, water and salt for all.” – Nelson Mandela
- “The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
- “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
- “I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
- “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
- “If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
- “Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
- “Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
- “Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
- “You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
- “Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
- “Delete the negative; accentuate the positive!” – Donna Karan
- “It’s crazy how fast time flies and how things progress.” – Nathan Chen
- “The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
- “Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
- “Everything has beauty, but not everyone sees it.” – Confucius
- “A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
- “Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
- “A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
- “The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
- “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
- “I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
- “Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
- “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
- “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
- “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
- “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
- “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
- “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
- “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
- “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
- “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
- “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
- “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
- “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
- “There is little that can withstand a man who can conquer himself.” – Louis XIV
- “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
- “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
- “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
- “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese
- “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
- “Never do anything against conscience even if the state demands it.”– Albert Einstein
- “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
- “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
- “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
- “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
- “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
- “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
- “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
- “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
- “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch
- “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
- “The secret of getting ahead is getting started.” – Mark Twain
- “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe
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