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Wall Street Stages Comeback (August 6, 2024) – $ADT $CAT $INDP $KVUE $LTRN $LUMN $MODD $UBER Rise!

By John F. Heerdink, Jr.

Wall Street staged a remarkable comeback on Tuesday, August 6, 2024, with the Dow rallying 500 points, following a dramatic sell-off that had sent global markets into a tailspin the previous day. The recovery was also broad-based, with gains seen across various sectors, from smaller companies dependent on U.S. consumer spending to large multinationals more reliant on the global economy.

Market Rebound Highlights

In a stunning reversal of fortune, Wall Street shook off its Monday blues and staged a comeback on Tuesday, August 6, 2024. The S&P 500 rose by 2%, breaking its three-day losing streak, while the Nasdaq Composite climbed 2.3%. This rebound came as a relief to investors who had witnessed the market’s worst day in nearly two years just 24 hours earlier.

The dramatic turnaround was fueled by several factors:


* Stronger-than-expected profit reports from major U.S. companies boosted investor confidence.
* The Cboe Volatility Index (VIX), Wall Street’s “fear gauge,” retreated below 30 after spiking above 65 on Monday, signaling a calming of market nerves.
* Global markets, particularly in Japan, showed signs of recovery, helping to stabilize investor sentiment worldwide.

The small caps on the Russell 2000 closed at 2,064.30 (+1.23%) & The iShares Micro-Cap ETF (IWC) tried to keep up with its larger counterparts, but managed to only rise .77% closing at $114.86.

Japan’s Nikkei 225 Surge

Japan’s Nikkei 225 index experienced a remarkable turnaround, surging 10.2% on Tuesday – its strongest performance since October 2008. This dramatic rebound came just a day after the index suffered its most significant drop since 1987, plummeting 12.4%. The recovery in Japanese equities played a crucial role in bolstering global investor sentiment, demonstrating the interconnectedness of international markets and their influence on Wall Street’s performance.

Corporate Heroes of the Day

Several companies emerged as heroes in Tuesday’s market rally, with their strong performances helping to buoy investor sentiment. Kenvue (KVUE), the company behind Tylenol and Band-Aids, jumped an impressive 14% after reporting stronger-than-expected profits, partly due to higher product prices. Uber (UBER) rolled 7.9% higher, easily surpassing profit forecasts for the latest quarter. Meanwhile, Caterpillar (CAT) veered from an early loss to a gain of 3.6% after reporting stronger earnings than anticipated, despite weaker revenue. These positive corporate results played a crucial role in restoring confidence and contributing to the broader market rebound.

Yield Curve Rollercoaster

In a plot twist that would make even the most seasoned Wall Street traders scratch their heads, the Treasury market decided to play a game of “Opposite Day” on August 6. After days of rates dropping faster than a skydiver without a parachute, Treasuries suddenly seemed to remember they were supposed to be going up, not down. The 10-year yield, apparently feeling left out of the party, jumped 10 basis points to 3.89%, while its shorter cousin, the 2-year yield, followed suit, settling at 3.98%.

Despite this sudden change of heart, both yields are still lower than last week’s levels, with the 10-year yield down 25 basis points and the 2-year yield a whopping 38 basis points lower. It’s as if the yields are trying to limbo under last week’s bar, leaving investors to wonder if they should be dancing or ducking. Meanwhile, a $58 billion 3-year note auction met solid demand, proving that even in this topsy-turvy market, some folks still can’t resist a good Treasury sale. However the Fed’s tea leaves are still pointing towards a rate cut in September as a a recession may be in view.

AI Fuels Fiber Frenzy

In a plot twist that would make even the most ambitious sci-fi writers blush, Lumen Technologies (LUMN, $5, +93.05% and hit a high in the after market of $8.86) has found itself at the center of an AI-fueled gold rush. The company announced it had struck $5 billion worth of digital oil, with another $7 billion potentially on the horizon, all thanks to the insatiable appetite of our new AI overlords for fiber optics. It seems that in the race to create the next ChatGPT, tech giants have realized they need more than just clever algorithms – they need enough fiber to knit a sweater for the entire internet.

Kate Johnson, Lumen’s CEO, could barely contain her excitement, declaring this the beginning of “one of the largest expansions of the internet ever”. One can only imagine her gleefully rubbing her hands together, cackling “More fiber! More power!” as she plans to double the company’s intercity network miles. Meanwhile, Corning, Lumen’s new BFF in this fiber frenzy, is probably wondering if they should start mining sand to keep up with the demand for glass. As Lumen’s stock skyrocketed by 93%, leaving even the most caffeinated day traders dizzy, it’s clear that in the AI economy, the real winners are those who can untangle the web of connectivity faster than you can say “404 error”.

VP Watchlist Updates

Eupraxia Pharmaceuticals (EPRX, $2.55, -4.58% today and is up ), is a clinical-stage biotechnology company focused on the development of locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. The Company strives to provide improved patient benefit and has developed technology designed to deliver targeted, long-lasting activity with fewer side effects. DiffuSphere™, a proprietary, polymer-based micro-sphere technology, is designed to facilitate targeted drug delivery, with extended duration of effect, and offers multiple, highly tuneable pharmacokinetic (PK) profiles. This investigational technology can be engineered for use with multiple active pharmaceutical ingredients and delivery methods.Note that Eupraxia recently completed a Phase 2b clinical trial (SPRINGBOARD) of EP-104IAR for the treatment of pain due to osteoarthritis of the knee. The trial met its primary endpoint and three of the four secondary endpoints. Eupraxia has expanded the EP-104 platform into gastrointestinl disease with the Phase 1b/2a RESOLVE trial for treating EoE. Eupraxia is also developing a pipeline of later- and earlier-stage long-acting formulations. Potential pipeline indications include candidates for other inflammatory joint indications and oncology, each designed to improve on the activity and tolerability of currently approved drugs.On June 5, Eupraxia announced that results from its Phase 2 study of EP-104IAR for the treatment of osteoarthritis of the knee will be presented at the upcoming European Alliance of Associations for Rheumatology (“EULAR”) European Congress of Rheumatology 2024 (the “Meeting”). The EULAR Meeting is being held in Vienna, Austria from June 12-15, 2024.On May 23, Eupraxia announced that regulators in Australia and Canada have cleared the Company’s request to expand its Phase 1b/2a RESOLVE trial, which is evaluating the safety and efficacy of EP-104GI as a treatment for eosinophilic esophagitis (“EoE”). For further details about Eupraxia, please visit the Company’s website at: www.eupraxiapharma.com.


Shares of Lantern (LTRN), an artificial intelligence (“AI”) company developing targeted and transformative cancer therapies using its proprietary RADR® AI and machine learning (“ML”) platform with multiple clinical stage drug program, closed at $3.59, +1.99% and is up 3.06% at  $3.70 in the aftermarket.

On August 5, Lantern Pharma announced promising preliminary results from its Phase 2 HARMONIC™ clinical trial, evaluating LP-300 in combination with standard chemotherapy for never-smokers with advanced non-small cell lung cancer (NSCLC). As reported earlier today, August 5, the study has shown an impressive 86% clinical benefit rate in the initial patient group, offering hope for a patient population with limited treatment options. The proportion of never-smoking patients with non-small cell lung cancer (NSCLC) has been significantly increasing globally over the past 30 years, from 15% in the 1970s to 33% in the 2000s. The high proportion of never smokers with NSCLC in East Asian countries is of particular note with Japan estimated to be 33 to 40% of new cases and Taiwan at over 50% of new cases. Lantern has received regulatory approval to initiate the LP-300 clinical trial in multiple Asian countries, and has started activation of sites in Japan and Taiwan, including the National Cancer Center in Tokyo, a globally recognized center of cancer research excellence. Read the balance of the story. 

On July 10, Lantern announced a significant advancement towards the development of a diagnostic for its drug candidate LP-184. The diagnostic is currently based on qRT-PCR (quantitative real-time polymerase chain reaction) technology and is focused on quantifying the amount of PTGR1 RNA in patient tumor samples to assess the potential for sensitivity to Lantern’s drug candidate LP-184. The company plans to further develop and validate the assay for its use as a potential tool for patient selection in later stage clinical trials across a broad range of solid tumors that have shown sensitivity to LP-184. Panna Sharma, CEO of Lantern Pharma stated, “This milestone represents a significant leap forward in our precision oncology approach and in ensuring that we enrich our future LP-184 clinical trials with the patients we believe will be most likely to benefit. By working to develop a companion diagnostic for LP-184, we’re not just advancing a drug candidate; we’re paving the way for more personalized and effective cancer treatments for patients that have the highest likelihood of benefitting from the therapy. The planned use of biomarkers like PTGR1 in our clinical trials exemplifies our commitment to data-driven, patient-centric drug development.”Panna Sharma, CEO of Lantern, was interviewed recently on the ‘Today In Nashville’, a program hosted by Carole Sullivan and associated with Nashville’s WSMV 4, an NBC affiliate. Watch it here to learn more.On June 12, Lantern announced that the Japan Patent Office (JPO) has issued a Certificate of Patent for patent application no. 2021-513267 / registration no. 7489966 directed to Lantern Pharma’s drug candidate LP-284 ((+)N-hydroxy-N-(methylacylfulvene)urea). The Certificate of Patent entitled “Illudin Analogs, Uses Thereof, and Methods for Synthesizing the Same” covers molecule LP-284, including claims covering the new molecular entity. A Certificate of Patent is issued after JPO examinations have confirmed the merits of a patent request. Lantern values the broad protection this latest patent provides. Lantern estimates that LP-284 can have the potential to improve outcomes for 40,000 to 80,000 patients with blood cancers annually, with a global annual market potential of $4 Billion USD.


Shares of Indaptus Therapeutics, Inc. (Nasdaq: INDP) closed at $1.70, +3.03% and is up +10.46% at $1.99 in the aftermarket.  Indaptus is a company with the ability to harness both the body’s innate and adaptive immune responses, believes that they are uniquely positioned to revolutionize the treatment of cancer and certain infectious diseases. Indaptus Therapeutics has evolved from more than a century of immunotherapy advances. The Company’s novel approach is based on the hypothesis that efficient activation of both innate and adaptive immune cells and pathways and associated anti-tumor and anti-viral immune responses will require a multi-targeted package of immune system-activating signals that can be administered safely intravenously (i.v.). Indaptus’ patented technology is composed of single strains of attenuated and killed, non-pathogenic, Gram-negative bacteria producing a multiple Toll-like receptor (TLR), Nucleotide oligomerization domain (Nod)-like receptor (NLR) and Stimulator of interferon genes (STING) agonist Decoy platform. The products are designed to have reduced i.v. toxicity, but largely uncompromised ability to prime or activate many of the cells and pathways of innate and adaptive immunity. Decoy products represent an antigen-agnostic technology that have produced single-agent activity against metastatic pancreatic and orthotopic colorectal carcinomas, single agent eradication of established antigen-expressing breast carcinoma, as well as combination-mediated eradication of established hepatocellular carcinomas and non-Hodgkin’s lymphomas in standard pre-clinical models, including syngeneic mouse tumors and human tumor xenografts.On June 4, Indaptus announced that its Chief Medical Officer, Roger Waltzman, M.D., will present an update on the Company’s lead product candidate, Decoy20, at the 7th Annual Next-Gen Immuno-Oncology Conference in Boston on June 20-21, 2024. Dr. Waltzman will present preliminary results from the Company’s ongoing Phase 1 study of Decoy20, an intravenous treatment using killed bacteria designed to broadly stimulate the immune system, in patients with advanced solid tumors.On June 3, Indaptus announced updated data from its ongoing Phase 1 clinical trial of Decoy20 in patients with solid tumors. The data were featured in a poster presentation at the American Society of Clinical Oncology (ASCO) Annual Meeting on June 1 in Chicago, Illinois.

 

Shares of ADT Inc. (ADT), a leading provider of monitored security and automation solutions for residential and small business customers in the United States and Canada, closed at $7.07, +2.91% after establishing a new 52-wk high of $7.92 during intraday trading recently.

On Aug. 1, ADT reported its second quarter results for 2024 that read like a thrilling spy novel, complete with mysterious numbers and covert operations. The company reported a 3% increase in total revenue, reaching $1.2 billion – apparently, securing homes is more lucrative than ever in our paranoid future. Their recurring monthly revenue (RMR) grew by 2% to $355 million, proving that once ADT gets its foot in your door, it’s there to stay

The company boasted “strong customer retention” with a gross revenue attrition of 12.9%, which in ADT speak means they’re only hemorrhaging about 1 in 8 customers. Their “revenue payback” sits at 2.2 years, suggesting it takes that long for customers to stop regretting their decision to sign up.

In a plot twist worthy of a summer blockbuster, ADT’s GAAP income from continuing operations dropped by $54 million. But fear not, shareholders! Their “adjusted” income increased by $3 million. It seems ADT has mastered the art of financial alchemy, turning red numbers green faster than you can say “creative accounting”.

CEO Jim DeVries, channeling his inner motivational speaker, declared that ADT’s success is “powered by our employees’ dedication to the proposition that every second counts.” One can only imagine the intense pressure of working in an environment where bathroom breaks are timed to the millisecond.[

 
 

Modular Medical, Inc. (NASDAQ: MODD, $1.48, +1.37%), is a development-stage, insulin delivery technology company seeking to launch the next generation of user-friendly and affordable insulin pump technology. Using its patented technologies, the company seeks to eliminate the tradeoff between complexity and efficacy, thereby making top quality insulin delivery both affordable and simple to learn. Their mission is to improve access to the highest standard of glycemic control for people with diabetes taking it beyond “superusers” and providing “diabetes care for the rest of us.” Modular Medical was founded by Paul DiPerna, a seasoned medical device professional and microfluidics engineer. Prior to founding Modular Medical, Mr. DiPerna was the founder (in 2005) of Tandem Diabetes and invented and designed its t:slim insulin pump. More information is available at https://modular-medical.com.

 
On July 15, Modular Medical announced a proof-of-concept study with Gubra A/S (“Gubra”) in a high-fat, diet-induced obese (“DIO”) mouse model to explore the potential future use of the MODD1 pump platform to assist patients who struggle with tolerability, inconsistent efficacy, and cost of long acting GLP-1 therapies. “A recent study published by Blue Health Intelligence using data from a national dataset of private insurers found that about half of all patients prescribed a GLP-1 drug for weight loss discontinued after the first 12 weeks, with approximately 30% discontinuing in the first four weeks,” commented Jeb Besser, Chief Executive Officer of Modular Medical. “These discontinuations appear to be due to a combination of tolerability, cost, and inconsistent efficacy. We suspect that short-acting peptides may mitigate many of these side effects and dosage swings by better modulating dosage, but these therapies have generally been abandoned as “too difficult to use” because they required multiple doses per day to be effective. We see the potential for such dosing regimes to be greatly simplified and even improved by the use of pump technology to provide both a basal dose and boluses to control hunger. Using Gubra’s gold-standard DIO mouse model, MODD will seek to determine whether an existing FDA approved, short-acting peptide delivered from a pump platform can provide a more personalized and more tolerable solution for patients who found long acting GLP-1 drugs too difficult to tolerate, while delivering comparable glycemic control and weight loss, specifically for people with type 2 diabetes and obesity.” Learn more here.
 
On June 3, Modular Medical, Inc. announced that it is set to join the Russell Microcap Index at the conclusion of the 2024 Russell indexes annual reconstitution, effective when the U.S. market opens on July 1, 2024. Membership in the Russell Microcap Index, which remains in place for one year, means automatic inclusion in the appropriate growth and value style indexes. FTSE Russell determines membership for its Russell indexes primarily by objective, market-capitalization rankings and style attributes. Russell indexes are widely used by investment managers and institutional investors for index funds and as benchmarks for active investment strategies. Approximately $10.6 trillion in assets are benchmarked against Russell’s US indexes. Russell indexes are part of FTSE Russell, a leading global index provider. Also read the following

 

Quote of the Day

“When ambition ends, happiness begins.” – Thomas Merton

Economic Reports

On Monday, the ISM Non-Manufacturing Index for July came in hotter than a summer sidewalk, causing buyers to vanish faster than free samples at Costco. The Final July S&P Global US Services PMI Report also came in lower at 55.

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