Interest Rates & Oil Jumped As Stocks Headed South This Week – $CORT FSLY $LTRN $NARI $VIX Rise!

Happy Saturday!

I hope that you had a great first week of August and are out enjoying a beautiful weekend day. I am spending my last day in Sonoma and then heading back to San Francisco for the balance of the week. 

As for the broad markets this week, the stock indices headed decidedly south as a number of macroeconomic reports surfaced again including the Fitch Ratings’ downgrade of the US’s credit that disturbed the markets and investors alike and interest rates shot up on the long side of the curve. On Monday, the Chicago PMI report confirmed a rise to 42.8 in July. On Tuesday, the S&P Global US Manufacturing PMI report showed a move up to 49 in the final reading in July. The July ISM Manufacturing Index report also moved higher to 46.4% in July, but remains in contraction territory. The Total construction spending report also showed a rise to .5% M/M in June. The Total private construction report also clocked in with a move up .5% M/M. The total public construction report also confirmed a .3%M/M rise, while on a Y/Y basis total construction spending rose 3.5%. The JOLTS job openings report come in totaling 9.582M in June. On Wednesday, the weekly MBA Mortgage Applications Index report that showed a 3% drop, while purchase & refinance applications both dropped equally buy 3. The ADP Employment Change report came in 324k higher in private sector payrolls in July. The weekly EIA crude oil inventories came in with a 17.1M barrel draw. On Thursday, the Preliminary Q2 Productivity Report came in t 3.7%, while the preliminary Q2 Unit Labor Costs report came in at 1.6%. The Weekly Initial Claims report came in at 227k little higher and the Weekly Continuing Claims report clocked in at 1.7M. The Final July S&P Global US Services PMI report came in lower at 52.3. The June Factory Orders report came in at 2.3% & the July ISM Non-Manufacturing Index report casein at lower 52.7%. On Friday, the Nonfarm payrolls report came in 187k higher in July. The Nonfarm private payrolls report moved up by 172k in July, while the average hourly earnings increased by .4% in July & the unemployment rate dropped to 3.5%. The average workweek also decreased to 34.3 hours. As a result, the yield curve ended the week with  the 2-yr note yield down 7bps to 4.78% & the 10-yr note yield moved up 21bps to 4.06% & the 30-yr yield rose 18 bps to 4.21%. The U.S. Dollar Index also ended up at 1.02.01

The S&P 500 closed at 4,478.03 (-2.3%) for the week and is now up 16.1% YTD as 10 0f the 11 sectors ended in the red with only the energy sector rising 1.2% to end in the green on the strength of oil prices that closed up 2.5% this week at $82.62 & as Russia and Saudi Arabia played their manipulative games again restricting supply. Both Apple (AAPL, $181.99, -7.07% over the last 5-days) & Amazon (AMZN, $139.57, +5.57% over the last 5-days) led the earnings reports headlines throwing their collective weight around as Apple missed expectations and Amazon exceeded. Tesla (TSLA) closed at $253.86, -4.72% over the last 5-days.

The Dow 30 closed above the 35k level again closing at 35,065.60 (-1.1%) this week and is now up 5.8% YTD.  

The Nasdaq closed at 13,909.20 (-.2.8%) and remains up an amazing 32.9% YTD. San Francisco-based Fastly, Inc. (NYSE: FSLY, $9.80,+18.07% over the last 5-days), one of the world’s fastest edge cloud platforms, announced financial results for its second quarter ended June 30, 2023. Fastly highlighted the following: Record second quarter revenue of $122.8 million grew 20% year-over-year and exceeded the high end of our guidance range, Expanded market reach with new packaging and pricing for our core services, making it easy for companies of all sizes to try, buy, and use the powerful Fastly platform, & Repurchased $236.4 million in aggregate principal amount of convertible debt for $195.7 million, reflecting a 17% discount to par, and resulted in a $36.8 million net gain.

The Russell 2000 closed at 1,960.26 (-1.2%) for the week & is now up 11.1% YTD. The MicroCaps also moved higher this week as the iShares Micro-Cap ETF (IWC) closed at $112.82, -1.04% this week & is now up 4.63% YTD.  

Banks stocks pulled back this week after the recent run as The SPDR S&P Regional Banking ETF (KRE) moved down .33% over the last 5-days to close at $46.38 & the SPDR S&P Bank ETF (KBE) also moved down by .12% over the last 5-days to close at $41.89. 

The CBOE Volatility Index (^VIX) closed at $17.10 & up 25.46% over the last 5-days as volatility, fear, & worries increased along with the long term rates. 

As for the biotech sector closed lower again this week,  the Nasdaq Biotechnology ETF (IBB) closed at $127.35, -1.93% over the last 5-days and is now down 3% YTD, the NYSE ARCA Biotech Index (^BTK) closed at 5,178.79, -3% over the last 5-days and is now down 1.94% YTD, & the SPDR S&P Biotech ETF (XBI) closed at $81.22, -3.09% over the last 5-days, & is now down 2.14% YTD. The 52-week range is is now $72.44-$95.18.

On the bright side of the biotech sector this week, Menlo Park, CA’s Corcept Therapeutics Incorporated (NASDAQ: CORT, $31.19, +23.04% over the last 5-days%), a commercial-stage company engaged in the discovery and development of medications to treat severe endocrine, oncology, metabolism and neurology disorders by modulating the effects of the hormone cortisol, today reported results for the quarter ended June 30, 2023. Corcept highlighted the following: Revenue of $117.7 million, a 14 percent increase from second quarter 2022, an Increase in 2023 revenue guidance to $455 – $470 million, from $435 – $455 million, Net income per common share of $0.25 (diluted), compared to $0.24 in second quarter 2022, Cash and investments of $363.3 million as of June 30, 2023 and a Purchase of 6.6 million shares of Corcept common stock for $145.4 million.

Cathie Wood’s ARK Innovation ETF (ARKK) closed at $45.38, -8.21% over the last 5-days and is now up45.26% YTD.   

The iShares U.S. Healthcare ETF (IYH) closed at $278.10, -2.24% over the last 5-days and is now down 1.98% YTD.  

Inari Medical, Inc. (NASDAQ: NARI), $64.38 +10.87% over the last 5-days), a medical device company with a mission to treat and transform the lives of patients suffering from venous and other diseases, today reported financial results for its second quarter ended June 30, 2023. Inari highlighted the following: Generated revenue of $119.0 million in Q2 of 2023, up 28.3% over the same quarter last year, Delivered net income of $2.1 million in Q2 of 2023, compared to a $10.2 million net loss in Q2 of 2022, Announced commitment to PEERLESS II, a randomized controlled trial enrolling up to 1,200 patients, comparing mechanical thrombectomy with FlowTriever versus anti-coagulation alone for the treatment of pulmonary embolism, & Launched two new products, RevCore and T16 Curve, both purpose-built tools designed to address unmet needs in venous thromboembolism (“VTE”) patients.

From the world of cryptocurrency, Bitcoin (BTC) moved to $29,045.49 & down .63% over the course of the last 5-days at the time of the completion of this message. 

Gold prices closed at $1,946, -$25/oz over the last 5-days. Silver prices closed at $23.74, +$.46/oz over the last 5-days. 

VP Watchlist Updates

Lantern Pharma Inc. (NASDAQ: LTRN) closed at $4.84, +5.70% over the last 5-days. Lantern is developing targeted and transformative cancer therapies using its proprietary RADR® AI and machine learning (“ML”) platform with multiple clinical stage drug programs.Lantern believes that the use of machine learning, genomics and computational methods can help accelerate the development and commercialization of small molecule-based therapies. These drugs can be targeted to patients whose genomic profile identifies them as having the highest probability of benefiting from the drug, thereby creating the potential to achieve better outcomes.Their proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. Learn more about Lantern at the VP Watchlist Page.  

Lantern will host its second quarter 2023 operating and financial results webcast on Wednesday, August 9, 4:30 p.m. Eastern Time / 1:30 p.m. Pacific Time. Management intends to discuss the operating and financial results for the second quarter ended June 30, 2023 and provide guidance on upcoming milestones. Panna Sharma, President and Chief Executive Officer of Lantern Pharma, will lead the call and will be joined by other members of the management team. To register for the webcast, sign up at the link below: https://us06web.zoom.us/webinar/register/1016902973506/WN_h4QZ0ZyxR3mZZbNQxa2eMw.

Lantern also reported that it will participate and present at these upcoming conferences:

• Society of Neuro-Oncology/American Society of Clinical Oncology CNS Cancer Conference in San Francisco, CA, on August 10^th, 2023 from 5:30-7:30 p.m. PT.
  Presentation Title: LP-184, a novel acylfulvene-derived tumor site activated small molecule inhibits adult and pediatric CNS tumor cell growth

• International Conference on Drug Conjugates for Directed Therapy in Darmstadt, Germany on Thursday, August 24^th, 2023 from 9:45-10:15 a.m. CEST.
  Presentation Title: In-silico Approach for the Identification of ADC Targets with Improved Tumor Selectivity

On June 26, Lantern announced the company has published new findings in Oncotarget demonstrating drug candidate LP-284’s in vitro and in vivo antitumor potency for multiple non-Hodgkin’s lymphomas (NHL), including mantle cell lymphoma (MCL) and double-hit lymphoma (DHL). The journal article titled “LP-284 Targets Non-Hodgkin’s Lymphoma and DNA Damage Repair Deficiency” further supports LP-284’s development for NHL and advancement towards a first-in-human Phase 1 trial, which is anticipated for the second half of 2023. Non-Hodgkin’s lymphomas (NHL) remain one of the leading causes of cancer deaths globally and have an estimated 500,000 new cases globally, with NHL being the leading hematological malignancy in the US. Despite advances for NHL using combination and targeted therapies, nearly 20% to 40% of patients with certain subtypes still relapse after treatment. In aggressive subtypes of NHL, like MCL, nearly all patients relapse from standard-of-care (SOC) therapies. READ MORE at this link.

Lantern Pharma collaborates with leading institutions, researchers and companies to develop and deliver cancer therapies. i.e. Johns Hopkins, Fox Chase Cancer Center, Georgetown University, National Cancer Institute, Danish Cancer Society Research Center (DCRC), UT Health San Antonio. Learn more here. 

Shares of InMed Pharmaceuticals Inc. (INM), a leader in the research, development and manufacturing of rare cannabinoids, closed at $1.02, down 9.73% over the last 5-days.

• On July 20, InMed provided a commercial and manufacturing update on its subsidiary BayMedica LLC (“BayMedica”), a leading supplier of bioidentical rare cannabinoids to the Health and Wellness (“H&W”) market. Highlighting the following: $2.3M revenues (unaudited) in Q4 2023, representing 123% increase quarter over quarter (“QoQ”), Optimized and scaled up manufacturing processes over the last 12 months to meet increasing demand, & Third consecutive quarter with significant revenue growth. Eric A. Adams, InMed’s President and CEO stated, “We are very encouraged to see another strong quarter with (unaudited) revenues in excess of $2.3M, representing our third consecutive quarter with significant revenue growth. As demand for minor cannabinoids continues to increase, we see a potential path for BayMedica to become a profitable standalone business subsidiary and contribute margin to the pharmaceutical R&D parent.”

• On June 22, InMed announced safety and efficacy results from its Phase 2 clinical trial, called 755-201-EB (the “Phase 2 Trial”), for the treatment of symptoms related to EB. The purpose of the Phase 2 Trial was to evaluate the safety of INM-755 CBN cream, which consists of the control cream plus the active pharmaceutical ingredient CBN, and obtain preliminary evidence of efficacy in treating symptoms and healing wounds over a 28-day period in patients with EB. All four subtypes of inherited EB, including EB Simplex, Dystrophic EB, Junctional EB, and Kindler Syndrome were accepted into the Phase 2 Trial. The Phase 2 Trial used a within-patient, double-blind design whereby matched index areas were randomized to INM-755 CBN cream or control cream. The Phase 2 Trial enrolled a total of 19 patients. Data from one patient were excluded from efficacy analyses due to a significant protocol deviation. Of the 18 remaining patients whose data were considered reliable for clinical review, 17 were treated for chronic non-wound itch and one patient was treated for wound-related itch. The remaining endpoints (pain, wound healing) could not be analyzed due to too few enrollees with such symptoms. Of the 18 participants assessed, chronic itch improved by a clinically meaningful amount in 12 patients (66.7%). InMed will pursue strategic partnership opportunities for INM-755 in epidermolysis bullosa (“EB”) and other itch-related skin conditions.
• On June 1, InMed announced that results from a neurodegenerative disease study was presented in a scientific poster at the Canadian Neuroscience Meeting in Montreal from May 28-31, 2023. The InMed sponsored research, entitled “Cannabinoids modulate cytotoxicity and neuritogenesis in Amyloid-beta-treated neuronal cells”, demonstrated the ability of a specific rare cannabinoid (“pCBx”) in InMed’s 900 Series library of potential candidates that reduces amyloid toxicity and tau protein expression while enhancing neuronal cell growth and neuritogenesis markers in vitro, all considered to be important targets in the potential treatment of neurodegenerative diseases such as Alzheimer’s. The research was conducted in the laboratory of Dr. Ujendra Kumar and Dr. Rishi Somvanshi of the faculty of Pharmaceutical Sciences at the University of British Columbia. Studies have shown that cannabinoids, via their endocannabinoid receptors (CB1R and CB2R) that naturally occur in the human body and brain, reduce amyloid-beta (“Aβ”) toxicity, decrease p-tau protein expression and provide neurite outgrowth, thus improving neuronal viability and function. The results presented demonstrate the anti-apoptotic effects of pCBx and its role in neuritogenesis in the cells of neuronal origin and support the role of pCBx as a potential therapeutic intervention in neurodegenerative diseases.

• On May 31, our sister organization, Tribe Public, hosted a Presentation & Q&A Webinar Event titled “InMed Pharmaceuticals (NASDAQ: INM) Addressing The Increasing Demand For Rare Cannabinoids.” The event was co-hosted by InMed Pharmaceutical’s (NASDAQ: INM) CEO Eric A. Adams, MIBS, & BayMedica’s Jerry P. Griffin, VP, Sales and Marketing. InMed Pharmaceuticals (NASDAQ: INM, $1.34, +6.35%) is a global leader in the development, manufacturing, and commercialization of rare cannabinoids, which is developing a pipeline of rare cannabinoid therapeutics and dedicated to delivering new treatment alternatives to patients that may benefit from cannabinoid-based pharmaceutical drugs. i.e. Alzheimer’s Disease, Glaucoma, & a rare genetic skin disease, Epidermolysis Bullosa (EB). Together with its subsidiary, BayMedica LLC, the Company has unparalleled cannabinoid manufacturing capabilities to serve a spectrum of consumer markets, including pharmaceutical and health and wellness. If you missed this event, then you may now watch the event video at the Tribe Public YouTube Channel by clicking here. 

Thanks again for your attention this week. Please continue to share your thoughts, questions, & ideas as we move forward. 

In the meantime, please enjoy the balance of the weekly newsletter’s videos, quotes, updates and let’s find ways to crush it again as we move forward!

Investing & Inspiration

1. “Let us be grateful to people who make us happy, they are the charming gardeners who make our souls blossom.” –  Marcel Proust
2. “Strength and growth come only through continuous effort and struggle.” – Napoleon Hill
3. “Science may never come up with a better office communication system than the coffee break.” – Earl Wilson
4. “If everyone is moving forward together, then success takes care of itself.” – Henry Ford
5. “Hope is like the sun, which, as we journey toward it, casts the shadow of our burden behind us.”– Samuel Smiles
6. “Patriotism is supporting your country all the time, and your government when it deserves it.” – Mark Twain
7. “What would life be if we had no courage to attempt anything?” – Vincent Van Gogh
8. “The biggest risk is not taking any risk… In a world that is changing really quickly, the only strategy that is guaranteed to fail is not taking risks.” – Mark Zuckerberg
9. “Our lives improve only when we take chances – and the first and most difficult risk we can take is to be honest with ourselves.” – Walter Anderson
10. “Action is the foundational key to all success.” – Pablo Picasso
11. “Success is never final, failure is never fatal. It’s courage that counts.” – John Wooden
12. “Innovation distinguishes between a leader and a follower.” – Steve Jobs
13. “All the art of living lies in a fine mingling of letting go and holding on.” – Havelock Ellis
14. “The size of your success is measured by the strength of your desire; the size of your dream; and how you handle disappointment along the way.” – Robert Kiyosaki
15. “O, wind, if winter comes, can spring be far behind?” – Percy Bysshe Shelley
16. “Patience is a virtue, and I’m learning patience. It’s a tough lesson.” – Elon Musk
17. “Be true to your work, your word, and your friend.” – John Boyle O’Reilly
18. “Believe in yourself! Have faith in your abilities! Without a humble but reasonable confidence in your own powers you cannot be successful or happy.” – Norman Vincent Peale
19. “Surprise is the greatest gift which life can grant us.” – Boris Pasternak
20. “Logic will get you from A to B. Imagination will take you everywhere.” – Albert Einstein
21. “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
22. “Do exactly what you would do if you felt most secure.” – Meister Eckhart
23. “Life lived for tomorrow will always be just a day away from being realized.” – Leo Buscaglia
24. “Wisdom is oftentimes nearer when we stoop than when we soar.” – Wordsworth
25. “Take chances, make mistakes. That’s how you grow. Pain nourishes your courage. You have to fail in order to practice being brave.” – Mary Tyler Moore
26. “A single twig breaks, but the bundle of twigs is strong.” – Tecumseh
27. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
28. “There is little that can withstand a man who can conquer himself.” – Louis XIV
29. “The limits of the possible can only be defined by going beyond them into the impossible.” – Arthur C. Clarke
30. “Be faithful in small things because it is in them that your strength lies.” – Mother Teresa
31. “The future rewards those who press on. I don’t have time to feel sorry for myself. I don’t have time to complain. I’m going to press on.” – Barack Obama
32. “By three methods we may learn wisdom: First, by reflection, which is noblest; Second, by imitation, which is easiest; and third by experience, which is the bitterest.” – Confucius
33. “No man was ever wise by chance.” – Lucius Annaeus Seneca
34. “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
35. “It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare

36. “It does not matter how slowly you go as long as you do not stop.” – Confucius

37. “I want to put a ding in the universe.” – Steve Jobs

38. “Research is creating new knowledge.” – Neil Armstrong

39. “The reward for work well done is the opportunity to do more.” – Jonas Salk
40. “Man is a creative retrospection of nature upon itself.” – Karl Wilhelm Friedrich Schlegel
41. “There’s something about taking a plow and breaking new ground. It gives you energy.” – Ken Kesey

42. “Success seems to be largely a matter of hanging on after others have let go.” – William Feather

43. “The essential conditions of everything you do must be choice, love, passion.” – Nadia Boulanger

44. “More business is lost every year through neglect than through any other cause.” – Rose Kennedy

45. “Give me a lever long enough and a fulcrum on which to place it, and I shall move the world.” – Archimedes

46. “A person who won’t read has no advantage over one who can’t read.” – Mark Twain

47. “The best way out is always through.” – Robert Frost

48. “Start by doing what’s necessary; then do what’s possible; and suddenly you are doing the impossible.” – Francis of Assisi

49. “Without labor nothing prospers.” – Sophocles

50. “Intellectuals solve problems, geniuses prevent them.” – Albert Einstein

51. “This is the precept by which I have lived: Prepare for the worst; expect the best; and take what comes.” – Hannah Arendt

52. “The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller

53. “He who is brave is free.” – Lucius Annaeus Seneca

54. “When something is important enough, you do it even if the odds are not in your favor.” – Elon Musk

55. “I choose a block of marble and chop off whatever I don’t need.” – Auguste Rodin

56. “Hope is the only bee that makes honey without flowers.” – Robert Green Ingersoll

57. “He who knows that enough is enough will always have enough.” – Lao Tzu

58. “Plans to protect air and water, wilderness and wildlife are in fact plans to protect man.” – Stewart Udall

59. “In order to carry a positive action we must develop here a positive vision.” – Dalai Lama

60. “A hero is someone who understands the responsibility that comes with his freedom.” – Bob Dylan
61. “Inflation destroys savings, impedes planning, and discourages investment. That means less productivity and a lower standard of living.” – Kevin Brady
62. “If we give something positive to others, it will return to us. If we give negative, that negativity will be returned.” – Allu Arjun
63. “A good plan violently executed now is better than a perfect plan executed next week.” ~ George S. Patton
64. “You must do the things you think you cannot do.”- Eleanor Roosevelt
65. “Success is dependent on effort.” – Sophocles
66. “Nobody who ever gave his best regretted it.” – George Halas
67. “Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
68. “And when I breathed, my breath was lightning.” – Black Elk
69. “Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
70. “You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
71. “If you want a guarantee, buy a toaster.” – Clint Eastwood
72. “We are an impossibility in an impossible universe.” – Ray Bradbury
73. “If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
74. “I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
75. “Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
76. “It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
77. “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
78. Surprise is the greatest gift which life can grant us.” –  Boris Pasternak
79. “Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran 
80. “Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
81. “All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
82. “There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” –  Colin Powell
83. “There is more to life than increasing its speed.” – Mahatma Gandhi
84. “Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
85. “Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
86. “Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
87. “In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
88. “Life is too short for long-term grudges.” – Elon Musk
89. “There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
90. “Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
91. “The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
92. “Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
93. “Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
94. “But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
95. “Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
96. “Let there be work, bread, water and salt for all.” – Nelson Mandela
97. “The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
98. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
99. “I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
100. “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
101. “If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
102. “Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
103. “Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
104. “Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
105. “You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
106. “Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
107. “Delete the negative; accentuate the positive!” – Donna Karan
108. “It’s crazy how fast time flies and how things progress.” – Nathan Chen
109. “The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
110. “Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
111. “Everything has beauty, but not everyone sees it.” – Confucius
112. “A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
113. “Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
114. “A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
115. “The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
116. “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
117. “I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
118. “Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
119. “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
120. “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
121. “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
122. “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
123. “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
124. “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
125. “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
126. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
127. “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
128. “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
129. “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
130. “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
131. “There is little that can withstand a man who can conquer himself.” – Louis XIV
132. “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
133. “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
134. “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
135. “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese 
136. “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
137. “Never do anything against conscience even if the state demands it.”– Albert Einstein
138. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
139. “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
140. “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
141. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
142. “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
143. “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
144. “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
145. “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
146. “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch 
147. “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
148. “The secret of getting ahead is getting started.” – Mark Twain
149. “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe