S&P 500, Dow, Nasdaq Slide Amid Labor Market Woes and Government Shutdown Fears - Nov. 6, 2025 -( $DDOG $INTG $LLY $MODD $NOK $RIO $VIX Rise!) - Vista Partners LLC

Wall Street ended Thursday, November 6, 2025, sharply lower as surging volatility and renewed skepticism over tech valuations sent both large and small caps reeling. The Dow Jones Industrial Average finished down 0.84% at 46,912.30, the S&P 500 lost 1.1% to close at 6,720.32, and the Nasdaq Composite fell 1.9% to finish at 23,053.99. The Russell 2000 slipped to 2,418.82, -1.86% reflecting continued risk aversion among investors.

Macroeconomic Reports, Fed Update, Shutdown & Tariffs

Market sentiment was weighed down by fresh signs of weakness in the labor market and sluggish ISM services data, signaling the economy’s expansion may be faltering. Treasury yields pulled back—10-year notes ending at 4.089%—as investors priced in rising recession risks and a still-inverted yield curve, while the came down to 3.568%. The Federal Reserve made no new rate move today, with observers expecting the next FOMC decision later this month; rate cut hopes remain modest as the government shutdown continues unresolved into a fifth week. The Supreme Court also heard fresh arguments on Trump-era tariffs, hinting at a possible easing, though no final word yet—manufacturers remain on edge. The US government shutdown stretched deeper into the month, choking off full macroeconomic visibility.

Notable Stock Performances for Key Names

Eli Lilly (LLY): Closed at $937.44, +1.26% with shares holding up on GLP-1 optimism after agreeing to lower the their prices with the US Government.
NVIDIA: Down sharply to $188.08, -3.65% as a broad tech rout punished AI leadership stocks.
Nokia: (NOK) Ended at $6.95, +.88% moving somewhat sideways in an otherwise volatile session.
Amazon: Closed at $253.04, -2.86% lower as investors rotated out of growth.
Apple: Fell -.145 to $269.77 amid general tech selling pressure.
Tesla: Down 3.54% to $445.91, tracking broader electric vehicle and growth stock weakness.
Broadcom: Settled at $355.59, -.94% also under pressure as chip names fell with sentiment.
Meta: Dropped to $618.94, -2.67% with large-cap tech unable to escape the day’s downdraft.
McDonald’s: Went on a diet closing at $298.41, -2.38% however strong Q3 international sales supporting the golden arches.
Rio Tinto (RIO): Ended at $69.27, +.30% as global commodity markets remained subdued, however it has jumped 4.04% to $72.07 in the aftermarket
Oracle: Down 2.60% to $243.80.
Intel: Closed at $37.34, -2,97% pressured by cyclical headwinds in hardware.
Opendoor: Ended at $6.56 mirroring broad risk-off. Today, Opendoor Technologies Inc. (Nasdaq: OPEN) announced a special dividend distribution of warrants to holders of the Company’s common stock as of 5:00 p.m. New York City time on November 18, 2025 (the “Record Date”). The goal is simple: if management gets performance-based upside, shareholders should too – these warrants help achieve that. This program is intentionally structured as a new playbook for public-company alignment. Each registered shareholder as of the Record Date will receive three series of warrants – Series K, Series A, and Series Z – one (1) warrant of each series for every thirty (30) shares of the Company’s common stock held, rounded down to the nearest whole number. The details of these warrants are provided at this link and they plan for them to be listed and fully tradable. You can sell them on day one, or hold them and ride with the company as they rebuild the company.
Datadog, Inc. (DDOG, $190.82, +23.13%), the monitoring and security platform for cloud applications, reported that their third quarter revenue grew 28% year-over-year to $886 million, robust growth of larger customers, with about 4,060 $100k+ ARR customers, up from about 3,490 a year ago, & that they reached a milestone of over 1,000 integrations on the Datadog unified platform.

Market Barometers: Volatility, Commodities, and Crypto

VIX (CBOE Volatility Index): Rose 8.27% to 19.50, with anxiety clearly back on center stage.
Gold: Steady near $3,986.40/oz as traders sought a defensive posture.
Silver: Traded around $47.86/oz, fairly flat for the day.
Oil (WTI): Ended at $59.53/bbl, reflecting persistent supply questions.
Bitcoin: Traded near $101,167 with a 2.42% drop on the day, remaining highly volatile.

VP Watchlist Updates

Modular Medical, Inc. (Nasdaq: MODD., $5102, +3.40%), a leader in innovative insulin delivery technology, announced (Nov. 3) the successful validation of its Pivot controller line, a critical milestone in preparing for the commercial launch of its Pivot patch pump targeted for Q1 2026. The Pivot controller line validation further demonstrates manufacturing readiness for high-volume production, positioning Modular Medical to meet the growing demand in the diabetes treatment market for advanced technology.

Eupraxia Pharmaceuticals Inc. (NASDAQ: EPRX), a clinical-stage biotechnology company leveraging its proprietary Diffusphere™ technology to optimize local, controlled drug delivery for diseases with significant unmet need, announced (Nov. 4) its financial results for the third quarter of 2025 and provided a business update. Dr. James Helliwell, Chief Executive Officer of Eupraxia stated, “The compelling 52-week data from our RESOLVE trial reported this quarter further reinforce the potential of EP-104GI as a highly effective and durable treatment for eosinophilic esophagitis (EoE). Our highest-dose cohort delivered the largest improvements in tissue health outcomes and eosinophil reduction observed to date, with no additional safety concerns. Coupled with the successful completion of our $80.5 million financing supported by strong life-science focused investors, we are now well resourced to advance the EP-104GI program, including through topline data from the Phase 2b RESOLVE Trial expected in the third quarter of 2026.”

GeoVax Labs, Inc. (Nasdaq: GOVX), a clinical-stage biotechnology company developing multi-antigen vaccines and immunotherapies for infectious diseases and cancer, announced that it will report its financial results for the quarter ended September 30, 2025, after the close of U.S. markets on Thursday, November 13, 2025. Following the release, management will host a live conference call and audio webcast at 4:30 p.m. ET to review results and provide a business update.

Volato Group, Inc. (NYSE American: SOAR) and M2i Global, Inc. (MTWO, $.1025, +2.50%) announced (Oct. 16) the next phase of development of the digital and commercial infrastructure underpinning the U.S. Strategic Mineral Reserve (SMR). M2i initiated the SMR framework and technical specifications earlier this year. Volato is now applying its proven enterprise-software expertise to build and operationalize the secure technology backbone that will support critical mineral traceability, contracting, and compliance across the United States and allied nations. This infrastructure is being developed to serve as the market-facing layer of the U.S. Strategic Mineral Reserve initiative, providing miners, refiners, recyclers, manufacturers, and government entities with a trusted environment for physical critical mineral transactions—with verified provenance, end-to-end custody visibility, and regulatory compliance at its core.

Serina Therapeutics (NYSE American: SER, $4.33, +.07%) stands at a pivotal juncture as it harnesses fresh capital, regulatory momentum, and a sharpened communications strategy to propel its lead program, SER-252, into late-stage clinical testing for advanced Parkinson’s disease. The Alabama-based biotech is betting its proprietary POZ platform and reimagined approach to apomorphine delivery may redefine the treatment paradigm for patients who have exhausted standard oral therapies.

The InterGroup Corporation (NASDAQ: INTG, $36.29, +2.11%) reported results (Oct. 9) for the fiscal year ended June 30, 2025, including improved segment income in Hotel and Real Estate, increased liquidity, the alleviation of going-concern uncertainty at majority-owned subsidiary Portsmouth Square, Inc., and the Company’s return to compliance with Nasdaq listing requirements.

S&P 500, Dow, Nasdaq Slide Amid Labor Market Woes and Government Shutdown Fears – Nov. 6, 2025 -( $DDOG $INTG $LLY $MODD $NOK $RIO $VIX Rise!)

Macroeconomic Reports, Fed Update, Shutdown & Tariffs

Notable Stock Performances for Key Names

Market Barometers: Volatility, Commodities, and Crypto

VP Watchlist Updates

Sources

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