Wall Street ushered in Wednesday, November 5, 2025 with a refreshed dose of optimism—and just a dash of sophisticated exasperation—as major indices snapped back from recent turbulence driven by AI sector jitters and global macroeconomic suspense. The S&P 500 closed at 6,796.29, notching a gentle 0.37% gain and demonstrating that, on occasion, even Wall Street’s favorite benchmark appreciates a steady incline over a gymnastic leap. The Dow Jones Industrial Average ascended 225.76 points to finish at 47,311, up 0.48% on the session thanks to pronounced rebounds from industrials and, somewhat poetically, Caterpillar’s surprising 3.94% rally—a move surely envied by market cats still stuck in the bear trap. Nasdaq shrugged off its recent fever, climbing to 23,499.80, up 0.65%, with technology titans supporting the recovery even as valuations remained, as the Supreme Court would say, “under review”. The Russell 2000 Index took the opportunity to outperform, rising to 2,464.78 for a relatively robust 1.54% gain, perhaps emboldened by small-cap contrarians insisting that “size isn’t everything” after all. The VIX index, the market’s fear gauge that shot up recently, retreated to $18.01,-5.21% suggesting a muted appetite for drama (financial kind, not Emmy-winning).
Macroeconomic Reports and Federal Reserve
Wednesday’s ‘shutdown reduced’ parade of macroeconomic reports spotlighted a steady recovery in U.S. services activity, mild job market improvement, and subdued inflation expectations. Treasury yields drifted with the 2-yr ending at 3.638% and the 10-yr ending at 4.16% in anticipation of next week’s FOMC statement—expected November 13—where the market hopes Fed officials will clarify their stance on rate hikes amid “higher for longer” speculation.
Tariffs and Government Shutdown Drama
Global headlines circled around the Supreme Court’s live hearings on Trump-era tariffs, with legal arguments diving into whether the existing tariff regime can withstand judicial scrutiny. Washington’s shutdown saga simmered with bipartisan maneuvering, as November’s payroll data and upcoming CPI report loom. No new shutdown deadlines were breached today, but if Congress was a market sector, it would surely get downgraded on “headline risk” alone.
Noteworthy Company News and Performance
- Eli Lilly (LLY): Reached a new 52-week high at $955.41 before settling at $925.81, on continued enthusiasm for its diabetes and obesity drugs, and positive trial data released this week.
- NVIDIA: Closed at $195.21, down 1.75% as AI chip stocks took a breather, but long-term investors cited institutional accumulation and ongoing demand for Blackwell GPUs supporting future growth.
- Nokia: Shares edged higher to $6..85, +.59%.
- Amazon: Finished at $250.20, +.35% recently moving higher as bullish analyst sentiment centered on AWS growth, fueled by Anthropic’s massive cloud compute needs.
- Apple: Wrapped up at $270.14, +.04% during a quiet session after last week’s robust Q4 earnings.
- Tesla: Ended at $462.07, +4.01% recapturing investor favor after October’s rocky autopilot headlines.
- Broadcom: Closed at $358.98, up 2% as expansion in cloud and wireless markets balanced sector volatility.
- Meta: Closed at $635.95, +1.38% as surging AI investment continues to bolster long-term expectations despite near-term margin anxiety.
- McDonald’s (MCD): Rose to $305.67,+2.16% after reporting resilient performance in international markets.
- Rio Tinto Group (RIO): Metals fell back as iron ore prices retreated, with Rio Tintorising to $69.06, +1.72% reaffirming fiscal discipline in Q4 guidance (no new acquisitions announced).
- Oracle: Settled at $250.31, +.86% down nearly 12.52% over the last month, mirroring broader sector skepticism about high valuations despite massive new contracts and ambitious AI growth targets.
- Intel: Closed at $38.38, jumping 3.65% higher after recent volatility related to server chip deman.
- Opendoor (OPEN): Closed at $7.23, +4.48% prior to tomorrow’s earnings call.
Commodities and Crypto
Gold closed near $3,992.40 an ounce, silver at $47.93, and oil fell to $59.63 a barrel—each reflecting a world that finds comfort in tangible things, just as Bitcoin, recovered to $103,623.07, reminded traders that volatility is truly a digital art form.
VP Watchlist Updates
Modular Medical, Inc. (Nasdaq: MODD), a leader in innovative insulin delivery technology, announced (Nov. 3) the successful validation of its Pivot controller line, a critical milestone in preparing for the commercial launch of its Pivot patch pump targeted for Q1 2026. The Pivot controller line validation further demonstrates manufacturing readiness for high-volume production, positioning Modular Medical to meet the growing demand in the diabetes treatment market for advanced technology.
Eupraxia Pharmaceuticals Inc. (NASDAQ: EPRX), a clinical-stage biotechnology company leveraging its proprietary Diffusphere™ technology to optimize local, controlled drug delivery for diseases with significant unmet need, announced (Nov. 4) its financial results for the third quarter of 2025 and provided a business update. Dr. James Helliwell, Chief Executive Officer of Eupraxia stated, “The compelling 52-week data from our RESOLVE trial reported this quarter further reinforce the potential of EP-104GI as a highly effective and durable treatment for eosinophilic esophagitis (EoE). Our highest-dose cohort delivered the largest improvements in tissue health outcomes and eosinophil reduction observed to date, with no additional safety concerns. Coupled with the successful completion of our $80.5 million financing supported by strong life-science focused investors, we are now well resourced to advance the EP-104GI program, including through topline data from the Phase 2b RESOLVE Trial expected in the third quarter of 2026.”
GeoVax Labs, Inc. (Nasdaq: GOVX), a clinical-stage biotechnology company developing multi-antigen vaccines and immunotherapies for infectious diseases and cancer, announced that it will report its financial results for the quarter ended September 30, 2025, after the close of U.S. markets on Thursday, November 13, 2025. Following the release, management will host a live conference call and audio webcast at 4:30 p.m. ET to review results and provide a business update.
Volato Group, Inc. (NYSE American: SOAR, $1.70, +6.92%) and M2i Global, Inc. (MTWO, $.1025, +2.50%) announced (Oct. 16) the next phase of development of the digital and commercial infrastructure underpinning the U.S. Strategic Mineral Reserve (SMR). M2i initiated the SMR framework and technical specifications earlier this year. Volato is now applying its proven enterprise-software expertise to build and operationalize the secure technology backbone that will support critical mineral traceability, contracting, and compliance across the United States and allied nations. This infrastructure is being developed to serve as the market-facing layer of the U.S. Strategic Mineral Reserve initiative, providing miners, refiners, recyclers, manufacturers, and government entities with a trusted environment for physical critical mineral transactions—with verified provenance, end-to-end custody visibility, and regulatory compliance at its core.
Serina Therapeutics (NYSE American: SER, $4.33, +.07%) stands at a pivotal juncture as it harnesses fresh capital, regulatory momentum, and a sharpened communications strategy to propel its lead program, SER-252, into late-stage clinical testing for advanced Parkinson’s disease. The Alabama-based biotech is betting its proprietary POZ platform and reimagined approach to apomorphine delivery may redefine the treatment paradigm for patients who have exhausted standard oral therapies.
The InterGroup Corporation (NASDAQ: INTG) reported results (Oct. 9) for the fiscal year ended June 30, 2025, including improved segment income in Hotel and Real Estate, increased liquidity, the alleviation of going-concern uncertainty at majority-owned subsidiary Portsmouth Square, Inc., and the Company’s return to compliance with Nasdaq listing requirements.
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