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Vista Partners Weekly Market Wrap – Happy Labor Day Weekend!

By John F. Heerdink, Jr.
“We must let go of the life we have planned, so as to accept the one that is waiting for us.” – Joseph Campbell, American Author, March 26, 1904 – October 31, 1987


Happy Saturday All!

I hope that you had a great week investing in the markets and that you are out enjoying the long Labor Day Weekend.  Thank you again for your attention and I look forward to speaking to each and everyone of you soon.

As for the markets, it was somewhat of a quiet week in many respects as investors began to sneak out early and many more had vacated the investing world by Friday as they were headed to the beach one last time prior to getting back to school, work or both. The reduced trading volumes and unanswered messages were certainly proof of that. Even with wit this early departuture, overall it was generally a positive week as all but the Dow closed in the green while Nasdaq led the charge with a significant weekly gain. 7 of the 11 sectors closed up this week with the real estate sector popping 4% and only four cyclical sectors fell led by the financials’ 2.5% decline and the energy sector’s 1.4% drop as oil prices closed at $69.29, +.8% for the week, and is now up 42.7% YTD.

The indices closed as follows: the S&P 500 closed at 4,535.43 (+.6%) & is now up 20.7% YTD, the Dow 30 closed at 35,369.09 (-.2%) & now is up 15.6% YTD, & the Nasdaq closed at 15,363.52 (+1.5%) & is up 19.2% YTD. The small caps on the Russell 2000 also closed in positive territory at 2,292.05 (+.7%) following last week’s sizable 5.1% jump and is now up 16.1% YTD. The MicroCaps moved higher as the iShares Micro-Cap ETF (IWC) closed at $149.70 adding +.65% to last weeks +6.65% jump & is now up a stellar 25.36% YTD.

MACRO REPORTS – YIELDS 

Many more macroeconomic reports surfaced again this week. On Monday, the macroeconomic schedule delivered  the Pending Home Sales report that confirmed a drop by 1.8% month/month in July. 
On Tuesday,  the Conference Board’s Consumer Confidence Index report confirmed a drop to 113.8 in August. The Chicago PMI report for August showed a drop to 66.8. The S&P Case-Shiller Home Price Index report confirmed rise to 19.1% Y/Y in June. The FHFA Housing Price Index report showed a rise by 1.6% M/M in June. On Wednesday, the August ISM Manufacturing Index came in basically in line at 59.9%. The total construction spending report confirmed a rise by .3% M/M in July & the total private construction report showed a rise of .3% M/M while total public construction spending rose by .7% & up 9% on Y/Y basis. The ADP Employment Change report confirmed estimates of 374k jobs were added to private-sector payrolls in August significantly below expectations.  Total construction spending rose .3% M/M in July & the final IHS Market Manufacturing PMI for August cam in at 61.1 lower than the preliminary reading. On Thursday, the initial claims report for the week ending August 28 confirmed a drop by 14k to 340k , while continuing claims for the week ending August 21 fell by 160k to 2.748M. The trade deficit for July came in to $70.1B  The factory orders for manufactured goods report showed a rise by .4% M/M in July. The Q2 productivity report was lowered to 2.1%. On Friday, the August nonfarm payrolls report confirmed a rise of 235k  but this was about a third of the expected number. July nonfarm payrolls were also revised to 1,053,000 from 943k. The labor force participation rate came in flat at 61.7%. The ISM Non-Manufacturing Index for August fell to 61.7%.

The yield curve widened a bit this week. The 10-yr yield ended up 1 basis point wk/wk to close at 1.32%, while the 2-yr moved down 1 basis wk/wk closing at .208%. The U.S. Dollar Index moved lower from 93.45 to close at 92.68.

Next week, the macroeconomic schedule will serve the producer price index report and the consumer credit report.

STORIES YOU MAY HAVE MISSED

Verizon 5G Edge & Microsoft Azure Stack Edge Partnership Launches Cloud Computing Platform That Offers Storage & Compute Services

Walgreens To Increase Pay Recognizing Critical Role Of Team Members In Service

Coca-Cola Announces Retirement Of Longest-Serving Current Member Of Board Herbert A. Allen

The Home Depot’s Chief Sustainability Officer Ron Jarvis To Host An ESG Webcast On Sept 9

50 First-Year College Students Welcomed Into Visa’s Black Scholars & Jobs Program

FAANG’s STRONG AGAIN

The FAANG’s weekly returns were as follows: Apple (AAPL) closed at $154.30, +3.84%, Amazon (AMZN) closed at $3,478.05, +3.83% for the week, Alphabet (GOOG) closed at $2,895.50, +.16% for the week, Facebook (FB) closed at $376.26, +.97% this week & Netflix (NFLX) closed at $590.53/share, +5.66%. The MicroSectors FANG+ Index 3X Leveraged ETN (FNGU), which offers 3x leveraged exposure to an index of “FANG” companies, and other companies that exhibit similar characteristics, closed at $39.91, +9.31% for the week and over 21% for the last two weeks. 

EV- TECH -CHIPS

Leading EV car maker Tesla (TSLA) moved higher to close at $733.57, +3.04% & shares of Ford Motor Co. (F) closed at $12.89, -3.16% for the week.

Microsoft (MSFT) closed at $301.14, +.47% for the week after recently recording a new record high of $305.84.

Chip making giant NVIDIA Corporation closed $228.43, +.91% for the week and establishing a new record high of $229.86. Chipmaker and software infrastructure supplier Broadcom (BCOM) beat earnings and revenue expectation in the fiscal Q3 & guided revenue expectations for the quarter going forward.

MongoDB, Inc. (NASDAQ: MDB), the leading, modern general purpose database platform reported Q2 Fiscal 2022 report and recorded Total Revenue of $199 million, up 44% Year-over-Year & Continued Strong Customer Growth with Over 29,000 Customers as of July 31, 2021. Their stocks shot up to closes at $507.41, +26.33% on Friday eclipsing the $500 level for the first time ever!

Cathie Wood’s ARK Innovation ETF (ARKK) closed at $125.073, +2.49% for the week.

The Technology Select Sector SPDR Fund (XLK) closed at $159.36, +.86% for the week.

ADT, Inc, (ADT) closed at $8.73,+3.56% for the week. Hopefully Google’s (GOOG) partner is beginning to regain some form. 

Reddit was founded in San Francisco in 2005 and according to Reuters is targeting an IPO for early next year and a valuation of $15 billion plus. In a private round recently they were valued at $10B. 

DISNEY

Disney (DIS) closed at $181, +.48% for the week. Recently, DIS reported a better than expected Q3 earnings report. Disney is now moving content from its streaming service Hotstar to its ESPN+ and Hulu streaming platforms in the United States. Disney, with 174 million paying customers across its four streaming services, is slowly consolidating its content into a Disney Bundle, which will include ESPN+, Hulu, Disney+ and more than 100,000 movies, TV episodes as well as sports events. Sports content from Hotstar will move to ESPN+, and Hotstar movies, as well as TV shows, will migrate to Hulu.The Disney Bundle, which starts at $13.99 per month, will cost subscribers at least $167.88 for a year. Disney’s streaming users growth (Disney+) blasted through expectations checking in with 116M vs. the 113.1M. People cannot seem to do without their Star Wars and Marvel related content.

BIOTECH MARCHES HIGHER BUT ENDS ON SOUR NOTE

The Nasdaq Biotechnology ETF (IBB) closed at $175.81, +2.33% for the week, & is up 16.05% this year. The NYSE ARCA Biotech Index (^BTK) closed at 5,998.75, +1% for the week and is up +4.53% YTD. Somewhat in concert this week, the SPDR S&P Biotech ETF (XBI) closed at $134.19, adding 1/64% but is still off 4.68% for the year. The XBI’s 52-wk range is $100.64-$174.79.

GOLD & SILVER

Gold prices headed higher again to close at $1,830, up $11 from the $1,819 close last week and now $47 in two weeks & silver prices closed sharply higher at $24.75/oz., up $.68 from the $24.07/oz. close last Friday and close to $2 over the last couple of weeks.  Hecla Mining Company (NYSE: HL) closed $6.40, +4.23% for the week. 

MEMES REPORT

AMC Entertainment (AMC), closed at $44.02, +7.79% adding to the +18.691% previous weekly gain & GameStop (GME) closed at $202.75, -1.07% for the week. 

Virgin Galactic Holdings (SPCE) closed at $24.28, +6.79% settling significantly lower the relatively recent all-time high of $62.80.

Infamous ‘meme brokerage’ firm Robinhood Markets, Inc., (HOOD) moved higher this week closing at $43.35, -7.51% for the week.

Seanergy Maritime Holdings Corp. (SHIP) closed at $1.27, +.79% this week on top of +17.76% weekly gain last week. The ‘only pure-play Capesize ship-owner publicly listed in the US’, announced recently that its Board of Directors has authorized a share repurchase plan. Under the Plan, the Company may repurchase up to $17 million of its outstanding common shares, representing approximately 10% of the Company’s market capitalization as of August 10, 2021. Capsize rates continue to surge which should bold for them!

Bitcoin

Bitcoin $BTC.X moved higher again this week eclipsing the $50k level while settling at 49,897.86, +5.97% over the week.

NEXT WEEK

The markets will be closed on Monday for Labor Day and then we will be back for four regular trading sessions Tuesday – Friday next week. 

VP WATCHLIST UPDATES

Please review our complete VP Watchlist that includes Apple (AAPL), Disney (DIS), Tesla (TSLA) & a select group of emerging names.  The pages will allow you to learn more and keep up with these companies daily.

For now, please see the updates from five of the emerging companies from the VP Watchlist below:


  • Shares of INmune Bio, Inc. (NASDAQ: INMB) moved significantly higher over the week closing at $26.43, +31.95% this week, now up +53.12% in the last 2-weeks. The 52-wk range is $7.28 – $29.99. Not to shabby considering the stock was in the $9 range when we highlighted them in May of this year!
    • On Wednesday, Aug. 4th, INmune Bio, Inc. reported its financial results for the second quarter ended June 30, 2021 and provided a business update. Raymond J Tesi, M.D., CEO/CMO of INmuneBio (INMB) stated, “We continue our planning and setup for a Phase 2 clinical trial of our lead candidate, XPRO™ (Xpro1595™), in patients with mild Alzheimer’s disease, which we plan to initiate by year-end. We have already demonstrated that XPRO™ can reduce neuroinflammation and decreases biomarkers of neurodegeneration and improve synaptic function. If successful in Phase 2, we believe XPRO™ has the potential to be among the most significant advancements in the treatment of Alzheimer’s Disease (AD) and other neurodegenerative diseases in many years. At the Alzheimer’s Association International Conference last week, we introduced a new biomarker – Apparent Fiber Density (AFD), a measure of axonal integrity measured by MRI. XPRO™ increases AFD in patients receiving 1mg/kg/week. We believe the novel non-invasive white matter analytics of white matter free water and apparent fiber density will be very useful in the development of XPRO™ in AD, Treatment Resistant Depression (TRD) and the many other CNS indications we hope to attack in the future. Last month, we treated the first patient in the first Phase 1 clinical trial of our NK cell priming platform, INKmune, in high-risk myelodysplastic syndrome (MDS). We are calling INKmune a pseudokine because, in vitro, it converts the resting NK cells into memory-like NK cells that can kill cancer cells as well or better than NK cells treated cytokines such as IL-12, IL-15 and IL-18 alone or in combination.”
    • On July 26th, INmune Bio announced the design of its upcoming Phase 2 clinical trial of XProTM in patients diagnosed with mild Alzheimer’s disease (AD) at AAIC. The announcement was accompanied by the release of additional biomarker data from the Phase 1b AD trial that shows improvement in white matter (myelinated axons) that degenerate in AD patients. READ MORE. 
    • On July 22, LUMICKS, a leading next generation life science tools company renowned for its innovative platforms for Dynamic Single-Molecule and Cell Avidity analysis, announced that it has installed its ground-breaking z-Movi® Cell Avidity Analyzer at INmune Bi0. INmune Bio is employing the z-Movi cell avidity analysis platform to demonstrate that the mechanism of action of the tumor-priming is the increase in NK cell:tumor cell avidity. Early data acquired by the z-Movi support their hypothesis that increased cell avidity enhances NK cell killing of tumor cells. This allows screening of batches of INKmune for potency and provides a potential biomarker of in vivo activity by measuring the tumor avidity of NK cells isolated from patients before and after INKmune treatment.
    • On July 14th, INmune Bio announced that it has entered into a definitive agreement with one healthcare focused institutional investor and one family office for the purchase and sale of 1,818,182 shares of its common stock at a price of $22 per share for gross proceeds of approximately $40 million in a registered direct offering. The closing of the offering is expected to occur on or about July 16, 2021, subject to the satisfaction of customary closing conditions. A.G.P./Alliance Global Partners is acting as the sole placement agent for the offering. INmune Bio intends to use the net proceeds from this offering for working capital and general corporate purposes and to advance the development of its product candidates and expand its pipeline. This includes the completion and data readout from the Company’s planned Phase 2 clinical trial of its lead clinical candidate, XPro1595, in patients suffering from Alzheimer’s disease, which is expected to commence by the end of 2021. “With this investment, we expect the Company’s Phase II program in Alzheimer’s disease is completely funded said RJ Tesi MD, CEO of Inmune Bio.
    • On July 12th,  INmune Bio, Inc. announced that the first patient has been treated in the company’s Phase 1 clinical trial of its Natural Killer (NK) cell priming platform, INKmune, as a potential treatment for high-risk myelodysplastic syndrome (MDS). This Phase 1 open label study will enroll nine patients with a confirmed diagnosis of MDS with excess blasts in a 3×3 dose escalation protocol. The primary endpoint is the safety and tolerability of INKmune when administered intravenously. Most secondary endpoints are biomarkers and include the change in percentage of blasts in peripheral blood and bone marrow, the change in autologous NK cell activity and functional maturity into tumor-induced memory-like NK cells in vivo. The overall response rate using WHO criteria, and duration of response will also be reported. READ MORE.
    • On July 7th, The Maxim Group’s analyst raised his price target from $32 to $42 today.
    • On June 14th, INMB announced that it had entered into a new $15M credit facility with Silicon Valley Bank (SVB) and an affiliate of SVB Financial Group. INmune intends to use the proceeds from the facility to partially fund the buyout of an option held by Xencor, Inc.(XNCR), resulting from INmune’s in-licensing of XPro1595 (now known by its generic name, pegipanermin) in October 2017. XPro1595 is a next-generation inhibitor of tumor necrosis factor (TNF) that uses a dominant-negativeTNF technology that is very different from approved TNF inhibitors that block the effects of both soluble and trans-membrane TNF. Pegipanermin neutralizes soluble TNF, without affecting trans-membrane TNF or TNF receptors. XPro1595 could have substantial beneficial effects in patients with Alzheimer’s and other neurodegenerative diseases by decreasing neuroinflammation. Total consideration to be paid to Xencor by INmune is $18.3 million, comprised of $15 million of cash and $3.3 million of INMB shares at a price of $17.14 resulting in the issuance of 192,533 shares. Pursuant to the original 2017 in-licensing agreement, INmune granted Xencor an option to purchase an additional number of shares of common stock equal to 10% of INmune’s fully diluted company shares for a period of seven years. The retirement of the Xencor option eliminates an estimated 2.1 million shares of potential future common stock dilution upon exercise of the option.

    • On May 18th, I hosted Immune Bio’s CEO RJ Tesi at the Tribe Public Presentation & Q&A Event for a fascinating discussion and his presentation titled “Advancing Treatment To Repair Our Aging Innate Immune System to Fight Alzheimer’s.” Please view the event video here. 



  • InMed Pharmaceuticals, Inc. (NASDAQ: INM) is leading clinical-stage pharmaceutical company developing cannabinoid-based drug candidates for high unmet medical needs and IntegraSyn, a proprietary and cost effective manufacturing approach for synthesized rare cannabinoids. Please visit the INM page at our website to learn more and check out the videos section too.  
  • Shares of InMed closed trading this week at $2.30, -5.74% for the week. The 52-wk range is $2.05 -$8.94.
    • Eric. A. Adams, President and CEO of INM, and Dr. Eric Hsu, Senior Vice President of Pre-Clinical Research & Development, will present at H.C. Wainwright Ophthalmology Virtual Conference on Tuesday, August 17, 2021. Mr. Adams and Dr. Hsu will provide an overview of InMed’s ocular program including INM-088, a topical eye drop formulation under development for the treatment of glaucoma. The active pharmaceutical ingredient (“API”) in INM-088 is cannabinol, also known as CBN, a rare cannabinoid showing promise in its potential to provide neuroprotection and to reduce intraocular pressure of the eye.

    • On July 9th, Roth Capital Partners analyst Scott Henry, CFA issued an update report with. BUY Rating titled, “INM: Favorable Take on BayMedica LOI” that includes a $11.50 12-Month Price Target.
    • On July 2, InMed announced that it had closed the previously announced private placement and after deducting the placement agent fees and estimated offering expenses payable by the Company, the Company received net proceeds of approximately US$11 million. H.C. Wainwright & Co. acted as the exclusive placement agent for the private placement. Under the terms of the private placement, an aggregate of 4,036,327 common shares (or common share equivalents in lieu thereof) and warrants to purchase up to an aggregate of 4,036,327 common shares were purchased, at an effective purchase price of US$2.973 per common share (or common stock equivalent in lieu thereof) and associated warrant. The warrants have an exercise price of US$2.848 per share, are exercisable immediately and have a term of five years. InMed intends to use the net proceeds from the offering to continue pipeline development, advance business development activities and for general working capital purposes.

    • On June 29th, INM announced that it has entered into a non-binding letter of intent (the “LOI”) to acquire BayMedica Inc. (“BayMedica”), a private company based in Nevada and California that specializes in the manufacture and commercialization of rare cannabinoids. BayMedica is a revenue-stage biotechnology company leveraging its significant expertise in synthetic biology and pharmaceutical chemistry to develop efficient, scalable, and proprietary manufacturing approaches to produce high quality, regulatory-compliant rare cannabinoids for consumer applications. BayMedica is currently commercializing the rare cannabinoid CBC (cannabichromene) as a B2B supplier to distributors and manufacturers marketing products in the health and wellness sector. BayMedica is currently planning additional rare cannabinoid launches for the coming year. In addition to their manufacturing and commercial activities in the health and wellness arena, BayMedica is researching cannabinoid analogs as potential drug candidates for pharmaceutical purposes. Those BayMedica proprietary compounds are based upon the structures of naturally-occurring cannabinoids and are designed to either augment the potential therapeutic effect against specific diseases or enhance product safety, or both.

    • On Thursday, June 17th, InMed Pharmaceuticals (NASDAQ: INM) announced that its continued optimization of IntegraSyn™ has increased the cannabinoid yield to a level of 5 g/L, further improving the economics of this proprietary manufacturing approach in advance of large-scale production. InMed’s cannabinoid yield of 5 g/L significantly exceeds currently reported industry yields. The Company has continued to make important steps to further optimize the IntegraSyn™ manufacturing process, resulting in the improved yield of 5 g/L, surpassing InMed’s previously reported yield levels of 2 g/L, an already commercially viable yield. The impact of improved yield is a significant reduction in the overall cost of manufacturing due to greater amount of cannabinoid produced per batch. InMed is now focused on manufacturing scale-up to larger batch sizes in the second half of calendar year 2021. “We are very excited by these impressive yield levels that further validates the IntegraSyn™ manufacturing approach as a commercially viable solution for large-scale, pharmaceutical-grade GMP production of rare cannabinoids. While we continue to refine the process, we are now focused on advancing the program towards the next key milestones, including the manufacture of our first large-scale batch through a GMP-ready process in the coming months. We continue to believe InMed’s proprietary IntegraSyn™ approach will be one of the most important manufacturing processes for pharma-grade cannabinoids,” stated Eric A. Adams, President and Chief Executive Officer of InMed.


  • Shares of Natural-Killer cell (NKcell) focused biopharmaceutical firm Fate Therapeutics (FATE) closed at $72.98, +.47% for the week. The 52-wk high is $121.16.
    • After the close on Thursday Aug. 20th,  FATE highlighted positive interim clinical data from the Company’s FT516 and FT596 programs for patients with relapsed / refractory B-cell lymphoma. FT516 is the Company’s universal, off-the-shelf natural killer (NK) cell product candidate derived from a clonal master induced pluripotent stem cell (iPSC) line engineered with a novel high-affinity, non-cleavable CD16 (hnCD16) Fc receptor, which is designed to maximize antibody-dependent cellular cytotoxicity (ADCC), a potent anti-tumor mechanism by which NK cells recognize, bind and kill antibody-coated cancer cells. The Company’s FT596 program incorporates both the hnCD16 Fc receptor and a chimeric antigen receptor (CAR) targeting CD19, which is designed to enable multi-antigen targeting of tumor cells, as well as an IL-15 receptor fusion (IL-15RF) to enhance NK cell activity and survival.
    • August 4th, Fate reported business highlights and financial results for the second quarter ended June 30, 2021. Scott Wolchko, President and Chief Executive Officer of Fate Therapeutics stated, “We are very pleased with the early clinical safety and activity we have observed with our off-the-shelf, iPSC-derived NK cell programs in relapsed / refractory lymphoma and acute myeloid leukemia, where interim Phase 1 data indicate FT516 and FT538 are well tolerated and can deliver complete responses for patients. We look forward to sharing additional clinical data from our FT516 and FT596 programs in B-cell lymphoma at our upcoming investor event. Additionally, treatment of the first patient with FT819, the first-ever iPSC-derived T-cell therapy to undergo clinical investigation, is a landmark achievement and further demonstrates the Company’s leadership in off-the-shelf, iPSC-derived cell therapy and the versatility of its proprietary iPSC Product Platform.”
    • On Aug. 2 Fate announced that the first patient has been treated with FT819, an off-the-shelf chimeric antigen receptor (CAR) T-cell therapy targeting CD19+ malignancies. FT819 is the first-ever CAR T-cell therapy derived from a clonal master induced pluripotent stem cell (iPSC) line, a renewable cell source that enables mass production of high quality, allogeneic CAR T cells with greater product consistency, off-the-shelf availability, and broader patient accessibility. FT819 is engineered with several first-of-kind features designed to improve the safety and efficacy of CAR T-cell therapy.


  • Shares of Atossa Therapeutics, Inc. (Nasdaq: ATOS), a clinical-stage biopharmaceutical company seeking to discover and develop innovative medicines in areas of significant unmet medical need with a current focus on breast cancer and COVID-19, closed at closed at $3.75, +.54% for the week. 
    • On Thursday, September 2nd, Atossa Therapeutics, Inc. (Nasdaq:ATOS) announced that it has received approval from the Swedish Ethics Review Authority to begin a Phase 2 clinical study of oral Endoxifen for the reduction of mammographic breast density (MBD). MBD is an emerging public health issue affecting more than 10 million women in the United States and many more worldwide. Studies conducted by others have shown that MBD reduces the ability of mammograms to detect cancer and increases the risk of developing breast cancer. Additional studies show a correlation between reducing MBD and a reduction in the incidence of breast cancer. The study, known as the Karisma-Endoxifen study, is a Phase 2, randomized, double-blind, placebo-controlled, dose-response study of Atossa’s proprietary oral Z-Endoxifen in healthy premenopausal women with increased breast density. The primary objective of the study is to determine the dose-response relationship of daily oral Endoxifen on MBD reduction, with secondary endpoints to assess safety, and tolerability, and an exploratory endpoint to assess durability of the MBD changes. It will be conducted in Stockholm and will include approximately 240 participants who will receive daily doses of oral Endoxifen or placebo for six months. South General Hospital in Stockholm will be conducting the study. The study is being led by principal investigator Per Hall, M.D., Ph.D., Head of the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet.

    • On Aug 13th, Atossa announced financial results for the fiscal quarter ended June 30, 2021, and provided an update on recent company developments. “We continue to experience encouraging progress in our MBD and COVID-19 programs, with new regulatory approvals being granted in Sweden for a Phase 2 trial in MBD and authorization in Australia to commence a Phase 2 study of AT-H201 for respiratory illness associated with COVID-19. In the meantime, we continue to enjoy a strong balance sheet, which we have significantly expanded over the last three quarters and will facilitate our development plans over the near term. As we actively explore the possibility for strategic expansion into other areas where we might see near-term milestones and results, we also urge all of our shareholders to exercise their right to vote at our special stockholder’s meeting on September 7, 2021. We urge a vote in favor of the proposal to increase authorized shares, which will provide the Company with the flexibility to issue shares as part of these potential acquisitions, collaborations and partnerships, a common strategy successful biotech companies seeking to grow shareholder value employ in order to create a more attractive opportunity for all. We look forward to continuing to update our stockholders on these opportunities as they develop,” stated Dr. Steven Quay, Atossa’s President and Chief Executive Officer.
    • On July 29th, Atossa filed a proxy inviting shareholders to attend the Special Meeting of Stockholders of Atossa Therapeutics, Inc., which will be held virtually on September 7, 2021, at 9:00 a.m. Eastern time. This Special Meeting will be held in a virtual meeting format only. You can virtually attend the live webcast of the Special Meeting at http://www.viewproxy.com/AtossaTherapeutics/2021/SM. Only stockholders of record who held common stock at the close of business on the record date, July 29, 2021 (the “Record Date”), may attend virtually and vote virtually at the Special Meeting, including any adjournment or postponement thereof. At the Special Meeting, you will be asked to consider and vote upon approval of an amendment to the certificate of incorporation to increase the number of shares of authorized common stock by 100,000,000 shares. No other items of business are expected to be considered at the meeting, pursuant to the Company’s Bylaws. The enclosed Proxy Statement more fully describes the details of the business to be conducted at the Special Meeting. After careful consideration, our Board of Directors has unanimously approved the proposal and recommends that you vote FOR the proposal. After reading the Proxy Statement, please mark, date, and sign and return the enclosed proxy card in the accompanying reply envelope to ensure receipt by our tabulator. YOUR SHARES CANNOT BE VOTED UNLESS YOU SIGN, DATE AND RETURN THE ENCLOSED PROXY OR ATTEND THE SPECIAL MEETING VIRTUALLY. Stockholders of record on the record date may also vote on-line or by phone by following the instructions contained in the accompanying Proxy Statement.
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  • Shares of  INVO Bioscience, Inc. (INVO), a medical device company focused on creating alternative treatments for patients diagnosed with infertility and developers of INVOcell®, the world’s only in vivo Intravaginal Culture System, closed at $3.85.
    • On Aug.2, INVO announced the Company’s first Joint Venture INVO Center practice in the United States, based in Birmingham, Alabama, will officially open on August 9, 2021. Dr. Hammond commented, “With the opening of the country’s first INVOcell medical practice, we are advancing a core mission towards improving access to advanced fertility services for the many patients who would otherwise never have the opportunity. To date, we have already received numerous advanced inquiries via word of mouth and have dozens of patients scheduled for initial patient consultations who are eager to proceed with treatment. As we officially open the center next week, we expect to accelerate our marketing programs with the help of the INVO marketing team to enhance overall patient awareness around Innovative Fertility Specialists, An INVO Center.”

INVO

    • On June 30th, VP Watchlist company, INVO Bioscience, Inc. (NASDAQ: INVO) expanded their North American footprint as they announced on June 30th that they had signed a joint venture agreement in partnership with reproductive specialist Dr. Sue Ellen Carpenter, M.D. through its wholly-owned subsidiary, INVO Centers, LLC, to open an INVO clinic in Atlanta. The clinic, Bloom Fertility, is scheduled to open in the second half of 2021. INVO Bioscience will provide funding for start-up and operating costs and own 40% of the Atlanta Joint Venture. Dr. Sue Ellen Carpenter, MD, is Board Certified in Obstetrics and Gynecology. With over 30 years of experience in reproductive medicine, Dr. Carpenter’s specialties include in vitro fertilization, treating congenital anomalies associated with infertility, as well as endometriosis and polycystic ovarian syndrome. Noted for excellence in her field and a “Top Doctor, Atlanta 2019 and 2020″ she delivers lectures across the country and has published more than a dozen papers on reproduction and fertility. She is an active member of the American Society of Reproductive Medicine (ASRM) as well as the Georgia OB GYN Society. Note that INVO Bioscience has also signed clinic partnerships in Birmingham, Alabama and the San Francisco Bay area earlier this year, along with its Mexico partnership in late 2020, which is scheduled to open later this year. These clinics, through the utilization of the INVOcell technology, in addition to the multiple clinic and distribution partnerships throughout the world are bringing advanced fertility care and much needed expanded access to the millions of underserved people.
    • On June 15th, INVO Bioscience, Inc. (NASDAQ: INVO), announced further foundational progress as they appointed of Andrea Goren as the Company’s Chief Financial Officer. In a career approaching 27 years, Mr. Goren has extensive experience in numerous financial functions, including service as a public company CFO, company director, capital raising activities as well as mergers and acquisition experience. Mr. Goren has served as managing director and CFO of Phoenix Group, a New York City-based private equity firm specializing in micro-cap and nano-cap public companies. He served as vice president of Shamrock Group, the Roy Disney family private investment firm in London; and was a director at New York City-based Madison Capital Group, a corporate advisory firm focused on U.S. / European Union cross border transactions. Mr. Goren holds a Bachelor of Arts degree from Connecticut College in New London, Connecticut, and an MBA from the Columbia Business School in New York City.
    • On May 17, INVO announced financial results for the first quarter of 2021 ended March 31, 2021 and provides a business update. Steve Shum, Chief Executive Officer of INVO Bioscience stated, “This was an exciting start to the year 2021 for INVO Bioscience as we advanced our INVO Clinic strategy with the signing of our first U.S.-based INVOcell exclusive facility in Birmingham, Alabama, the signing of a partnership agreement to establish and operate a center in Northern California, and the completion of our product registration in Mexico. We expect these initial centers to become operational in the second half of the year. Throughout this year, we have expanded our real-world experience data and positive results with INVOcell, enhanced our online training tools, materials, and capabilities and have experienced a substantial increase in active training sessions for our international partners and distributors. We believe the combination of strong commercialization partnerships and company-owned clinics, both in the U.S. and around the world, is key to expanding INVOcell’s adoption within the fertility industry. In addition to the progress made executing new commercialization agreements, we have strengthened our marketing capabilities to support the INVOcell-only centers and our growing number of distribution partners. Meryle Lynn Chamberlain, a tenured women’s health and fertility solution marketing professional, joined us as Director of Marketing in March 2021, while Rebecca Messina, current Senior Advisor at McKinsey & Co. and former Global Chief Marketing Officer at both Uber and Beam Suntory joined our board of directors in April 2021. As we look to increase access to care and expand fertility treatment across the globe, our market positioning and overall strategies are more important than ever. The addition of Meryle Lynn and Rebecca will enhance our ability to successfully accomplish these goals. As we look to the remainder of 2021, we have set a number of key objectives, including the opening of our first company-owned clinics in Mexico and the United States. Additionally, we will seek to build our international revenues this year through our growing list of international distribution partners as they finish training, and we complete local product registration requirements. Of note, we are extremely pleased to see the initial INVO procedures performed recently in Spain and Malaysia, which reflects the groundwork done by our team in these specific markets, which we believe will help in further expanding the overall awareness of the potential outside of the U.S. Finally, we are continuing to advance our 5-day label expansion efforts with the FDA in the U.S. market with a goal of completing this effort in 2021. It remains our belief that there is strong global demand for fertility services and INVOcell is well-positioned through our growing, global footprint to play a key role in helping to turn the dream of creating a family for millions of people around the world into a reality through our accessible, efficient, and affordable fertility treatment.”

Dr. David Sable Portfolio Manager of The Special Situations Fund of AWM Investment Company

    • On May 11, a 13G was filed that confirms that David Sable’s (a former #IVF doc turned portfolio manager) Special Situations Fund of AWM Investment Company increased their ownership to 11.1% or 1,154,153 share ownership of INVO Bioscience (INVO). They held 625k/6.5% as of the 13G filing 2-12-2021. If you are not familiar with them, I believe if you do a relatively small amount sleuthing you will find out that they are one of the most successful multi-billion funds over the last 20-years, especially in finding small undiscovered microchips. I believe that they led the round of $13M at $3.20 a share in November 12, 2020 that pushed INVO uplist to the NASDAQ. Here’s the 13G filing. The company only has 10,424,229 shares issued and outstanding as of March 31, 2021.
    • Industry forecasts suggest that only 1% to 2% of the estimated 150 million infertile couples worldwide are currently being treated. INVO’s mission is to increase access to care and expand infertility treatment across the globe with a goal of improving patient affordability and industry capacity. Since January 2019, INVO Bioscience has signed commercialization agreements in the United States, India, as well as parts of Africa and Eurasia and Mexico for the INVOcell device.


Thanks again for your attention this week. Please continue to share your thoughts, questions, & ideas as we move forward. 

In the meantime, please enjoy the balance of the weekly newsletter’s videos, quotes, updates. 

Investing & Inspiration

  1. “We must let go of the life we have planned, so as to accept the one that is waiting for us.” – Joseph Campbell
  2. “Put your heart, mind, and soul into even your smallest acts. This is the secret of success.” – Swami Sivananda
  3. “I can’t change the direction of the wind, but I can adjust my sails to always reach my destination.” – Jimmy Dean
  4. “Companies have too many experts who block innovation. True innovation really comes from perpendicular thinking.” – Peter Diamandis
  5. “By failing to prepare, you are preparing to fail.” – Benjamin Franklin
  6. “We must let go of the life we have planned, so as to accept the one that is waiting for us.” – Joseph Campbell
  7. “We cannot solve our problems with the same thinking we used when we created them.” – Albert Einstein

  8. “When you’re an investor, you can look at the quantitative and qualitative elements of an investment, but there’s a third aspect: What you feel in your gut.” – Kevin O’Leary

  9. “Set your course by the stars, not by the lights of every passing ship.” – Omar N. Bradley
  10. “Do not take life too seriously. You will never get out of it alive.” – Elbert Hubbard
  11. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey 
  12. “Every good painter paints what he is.” – Jackson Pollock
  13. If you believe in yourself and have dedication and pride – and never quit, you’ll be a winner. The price of victory is high but so are the rewards.” – Bear Bryant
  14. “Your mindset matters. It affects everything – from the business and investment decisions you make, to the way you raise your children, to your stress levels and overall well-being.” – Peter Diamandis
  15. “You cannot have a positive life and a negative mind.” – Joyce Meyer 
  16. “Like wildebeest and zebra migration across the Serengeti, investment managers and consultants, too, have a habit of running together and, every now and then, changing direction.” – Sanjaya Baru
  17. “If people are anything but enthusiastic about the information or ideas that they’re sharing, they’re either not that invested in what they’re doing – or they’re not communicating that investment effectively.” – Ana Kasparian 
  18. “Life consists not in holding good cards but in playing those you hold well.” – Josh Billings 
  19. “Friend, there’s no greater investment in life than in being a people builder. Relationships are more important than our accomplishments.” – Joel Osteen
  20. “It’s only natural that the heavy users help contribute to the investment to keep the Web healthy. That is the most important concept of net neutrality.” – Lowell McAdam
  21. “The more sand that has escaped from the hourglass of our life, the clearer we should see through it.” – Jean Paul 
  22. “Eliminate emotion from your investment program.” -John C. Bogle

  23. “Modern medical advances have helped millions of people live longer, healthier lives. We owe these improvements to decades of investment in medical research.” – Ike Skelton

  24. “In every investment, before I get involved or invest, I always see what the mindset of the founder, the CEO, is.” – Zaza Pachulia
  25. “An investment said to have an 80% chance of success sounds far more attractive than one with a 20% chance of failure. The mind can’t easily recognize that they are the same.” – Daniel Kahneman
  26. “The return on investment in global health is tremendous, and the biggest bang for the buck comes from vaccines. Vaccines are among the most successful and cost-effective health investments in history.” – Seth Berkley
  27. “Few things in the world are more powerful than a positive push. A smile. A world of optimism and hope. A ‘you can do it’ when things are tough.” – Richard M. DeVos
  28. To be yourself in a world that is constantly trying to make you something else is the greatest accomplishment.” – Ralph Waldo Emerson
  29. “We all have dreams. But in order to make dreams come into reality, it takes an awful lot of determination, dedication, self-discipline, and effort.”  – Jesse Owens
  30. “The pessimist complains about the wind; the optimist expects it to change; the realist adjusts the sails.” – William Arthur Ward- American Writer, Born 1921
  31. “Once you replace negative thoughts with positive ones, you’ll start having positive results.” – Willie Nelson
  32. “The secret of your future is hidden in your daily routine.” – Mike Murdock
  33. “Work hard for what you want because it won’t come to you without a fight. You have to be strong and courageous and know that you can do anything you put your mind to. If somebody puts you down or criticizes you, just keep on believing in yourself and turn it into something positive.” – Leah LaBelle
  34. “Opportunity is missed by most people because it is dressed in overalls and looks like work”. -Thomas A. Edison
  35. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
  36. “Human behavior flows from three main sources: desire, emotion, and knowledge.” – Plato

  37. “We are what our thoughts have made us; so take care about what you think. Words are secondary. Thoughts live; they travel far.” – Swami Vivekananda

  38. “Success is not final, failure is not fatal: it is the courage to continue that counts.” – Winston Churchill
  39. “If you don’t know where you are going, any road will get you there.” – Lewis Carroll

  40. “Don’t worry about being a star, worry about doing good work, and all that will come to you.” – Ice Cube

  41. “It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare

  42. “Prediction is very difficult, especially if it’s about the future.” – Niels Bohr

  43. “It is indeed true that the stock market can forecast the business cycle.” -Paul Samuelson

  44. “The wisest rule in investment is: when others are selling, buy. When others are buying, sell. Usually, of course, we do the opposite. When everyone else is buying, we assume they know something we don’t, so we buy. Then people start selling, panic sets in, and we sell too.” – Jonathan Sacks

  45. “What lies behind you and what lies in front of you, pales in comparison to what lies inside of you.” – Ralph Waldo Emerson
  46. Each new generation born is in effect an invasion of civilization by little barbarians, who must be civilized before it is too late.” – Thomas Sowell
  47. “Life is 10% what happens to you and 90% how you react to it.” – Charles R. Swindoll
  48. “The truth is you don’t know what is going to happen tomorrow. Life is a crazy ride, and nothing is guaranteed.” – Eminem
  49. “View health as an investment, not an expense.” – John Quelch
  50. “Opportunity does not knock, it presents itself when you beat down the door.” – Kyle Chandler

  51. If you don’t know where you are going, any road will get you there.” – Lewis Carroll

  52. “Once you replace negative thoughts with positive ones, you’ll start having positive results.” – Willie Nelson

  53. “That which does not kill us makes us stronger.” – Friedrich Nietzsche
  54. “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
  55. “A problem is a chance for you to do your best.”– Duke Ellington
  56. “The best way to predict the future is to create it.” -Peter Drucker
  57. “I’m involved in the stock market, which is fun and, sometimes, very painful.” – Regis Philbin
  58. “Who owns the future? This is the question at the heart of every stock market.” – John Landgraf
  59. “One of the funny things about the stock market is that every time one person buys, another sells, and both think they are astute.” – William Feather
  60. “While I’m sure some millennials are concerned with the ethical issues involved in mining for diamonds, the main reason they steer clear of the gems is because, well, they’re a dumb investment.” – Ana Kasparian
  61. “The wisest rule in investment is: when others are selling, buy. When others are buying, sell. Usually, of course, we do the opposite. When everyone else is buying, we assume they know something we don’t, so we buy. Then people start selling, panic sets in, and we sell too.” – Jonathan Sacks
  62. We must shift our thinking away from short-term gain toward long-term investment and sustainability, and always have the next generations in mind with every decision we make.” –  Deb Haaland

  63. “The only way to have a friend is to be one.” –  Ralph Waldo Emerson

  64. “If you believe in yourself and have dedication and pride – and never quit, you’ll be a winner. The price of victory is high but so are the rewards.” – Bear Bryant

  65. “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” -Liya Kebede

  66. “Success is not final, failure is not fatal: it is the courage to continue that counts.” – Winston Churchill

  67. “Our greatest glory is not in never falling, but in rising every time we fall.” – Confucius
  68. “Give me a lever long enough and a fulcrum on which to place it, and I shall move the world.” – Archimedes
  69. “Who controls the past controls the future. Who controls the present controls the past.” – George Orwell
  70. “If you get up in the morning and think the future is going to be better, it is a bright day. Otherwise, it’s not.” – Elon Musk
  71. The pessimist complains about the wind; the optimist expects it to change; the realist adjusts the sails.” – William Arthur Ward
  72. “Start where you are. Use what you have. Do what you can.” – Arthur Ashe
  73. “Netflix, Amazon, iTunes – whatever platforms emerge – we are looking at as having the same potential that home video had for the movie business. Which means there are entirely new opportunities to monetize our capital investment in content and do so in ways that work for distributors, for consumers and for creators.” – Bob Iger
  74. “When you have no one to answer to, vendetta as investment strategy is as legitimate as anything.” – Carl Icahn
  75. “No other investment yields as great a return as the investment in education. An educated workforce is the foundation of every community and the future of every economy.” – Brad Henry
  76. “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
  77. “Modern medical advances have helped millions of people live longer, healthier lives. We owe these improvements to decades of investment in medical research.”– Ike Skelton
  78. “Stock market goes up or down, and you can’t adjust your portfolio based on the whims of the market, so you have to have a strategy in a position and stay true to that strategy and not pay attention to noise that could surround any particular investment.” – John Paulson
  79. “Your mindset matters. It affects everything – from the business and investment decisions you make, to the way you raise your children, to your stress levels and overall well-being.” – Peter Diamandis
  80. “Inflation destroys savings, impedes planning, and discourages investment. That means less productivity and a lower standard of living.” – Kevin Brady
  81. “Cash – in savings accounts, short-term CDs or money market deposits – is great for an emergency fund. But to fulfill a long-term investment goal like funding your retirement, consider buying stocks. The more distant your financial target, the longer inflation will gnaw at the purchasing power of your money.”  – Suze Orman
  82. “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
  83. “I think you have to learn that there’s a company behind every stock and there’s only one real reason why stocks go up. Companies go from doing poorly to doing well or small companies grow to large companies.” – Peter Lynch
  84. “Historically, there has been a bull market in the commodities every 20 or 30 years.” – Jim Rogers
  85. “The markets generally are unpredictable, so that one has to have different scenarios. The idea that you can actually predict what’s going to happen contradicts my way of looking at the market.” – George Soros
  86. “Stop trying to predict the direction of the stock market, the economy or the elections.” – Warren Buffett
  87. “An important key to investing is to remember that stocks are not lottery tickets.” – Peter Lynch
  88. “Learn everyday, but especially from the experiences of others. It’s cheaper!” – John Bogle
  89. “When purchasing depressed stock in troubled companies, seek out the ones with the superior financial positions and avoid the ones with loads of bank debt.” – Peter Lynch
  90. “No stock price is too low for bears or too high for bulls.” –  John F. Heerdink, Jr.
  91. “Investment is most successful when it is most businesslike.” – Ben Graham
  92. “Value stocks are about as exciting as watching grass grow, but have you ever noticed just how much your grass grows in a week?” – Christopher Browne
  93. “Even the intelligent investor is likely to need considerable willpower to keep from following the crowd.” – Benjamin Graham
  94. “Individual who cannot master their emotions are ill-suited to profit from the investment process.” – Benjamin Graham
  95. “I made my first investment at age eleven. I was wasting my life until then.” – Warren Buffet
  96. “I don’t look to jump over seven-foot bars; I look around for one-foot bars that I can step over.” — Warren Buffett
  97. “There are only three measurements that tell you nearly everything you need to know about your organization’s overall performance: employee engagement, customer satisfaction, and cash flow. It goes without saying that no company, small or large, can win over the long run without energized employees who believe in the mission and understand how to achieve it.” – Jack Welch, former CEO of GE
  98. “Opportunities come infrequently. When it rains gold, put out the bucket, not the thimble” ― Warren Buffett
  99. “If you buy things you do not need, soon you will have to sell things you need.” – Warren Buffet
  100. “How many millionaires do you know who have become wealthy by investing in savings accounts? I rest my case.” — Robert G. Allen
  101. “It’s far better to buy a wonderful company at a fair price, than a fair company at a wonderful price.” – Warren Buffett
  102. “A market downturn doesn’t bother us. It is an opportunity to increase our ownership of great companies with great management at good prices.” — Warren Buffett
  103. “Every once in a while, the market does something so stupid it takes your breath away.” — Jim Cramer
  104. “The person who starts simply with the idea of getting rich won’t succeed; you must have a larger ambition.” — John D. Rockefeller
  105. “Know what you own, and know why you own it.” – Peter Lynch
  106. “Although it’s easy to forget sometimes, a share is not a lottery ticket… it’s part ownership of a business.” – Peter Lynch
  107. “Wise spending is part of wise investing. And it’s never too late to start.” – Rhonda Katz

  108. “Invest for the long haul. Don’t get too greedy and don’t get too scared.” – Shelby M.C. Davis

  109. “Fear incites human action far more urgently than does the impressive weight of historical evidence.”
    -Jeremy Siegel

  110. With a good perspective on history, we can have a better understanding of the past and present, and thus a clear vision of the future.” — Carlos Slim Helu
  111. “If we like a business, we’re going to buy as much of it as we can and keep it as long as we can. And when we change our mind, we don’t take half measures.” – Warren Buffett
  112. “The most contrarian thing of all is not to oppose the crowd but to think for yourself.” — Peter Thiel
  113. “Never depend on a single income, make an investment to create a second source.” Warren Buffet“Games are won by players who focus on the playing field –- not by those whose eyes are glued to the scoreboard.” ― Warren Buffett
  114. “The key to making money in stocks is not to get scared out of them.” – Peter Lynch
  115. “Courage taught me no matter how bad a crisis gets … any sound investment will eventually pay off.” — Carlos Slim Helu
  116. “Investing puts money to work. The only reason to save money is to invest it.” – Grant Cardone
  117. “As time goes on, I get more and more convinced that the right method of investment is to put fairly large sums into enterprises which one thinks one knows something about and in the management of which one thoroughly believes.” — John Maynard Keynes
  118. “Given a 10% chance of a 100 times payoff, you should take that bet every time.” — Jeff Bezos
  119. “Money is always eager and ready to work for anyone who is ready to employ it.” ― Idowu Koyenikan
  120. “The secret to investing is to figure out the value of something – and then pay a lot less.” – Joel Greenblatt
  121. “We don’t have an analytical advantage, we just look in the right place.” – Seth Klarman
  122. “Men, it has been well said, think in herds. It will be seen that they go mad in herds, while they only recover their senses slowly, and one by one.” – Charles Mackay
  123. “It’s not whether you’re right or wrong that’s important, but how much money you make when you’re right and how much you lose when you’re wrong.” – George Soros
  124. “In investing, what is comfortable is rarely profitable.” — Robert Arnott
  125. “Don’t look for the needle in the haystack. Just buy the haystack!” — John Bogle
  126. “No Price is too low for a bear or too high for a bull.” — Anonymous
  127. “Investment is an asset or item that is purchased with the hope that it will generate income or appreciate in the future.” — Anonymous
  128. “Behind every stock is a company. Find out what it’s doing.” — Peter Lynch
  129. “Wise spending is part of wise investing. And it’s never too late to start.” –Rhonda Katz
  130. “If there is one common theme to the vast range of the world’s financial crises, it is that excessive debt accumulation, whether by the government, banks, corporations, or consumers, often poses greater systemic risks than it seems during a boom.” — Carmen Reinhart
  131. “It amazes me how people are often more willing to act based on little or no data than to use data that is a challenge to assemble.” ― Robert Shiller
  132. “A bull market is like sex. It feels best just before it ends.” — Barton Biggs
  133. “The investor’s chief problem — even his worst enemy — is likely to be himself.” — Benjamin Graham
  134. “No profession requires more hard work, intelligence, patience, and mental discipline than successful speculation.” – Robert Rhea
  135. “The most contrarian thing of all is not to oppose the crowd but to think for yourself.” — Peter Thiel
  136. “Money is like a sixth sense – and you can’t make use of the other five without it.” – William Somerset Maugham
  137. “Compound interest is the eighth wonder of the world. He who understands it, earns it. He who doesn’t, pays it.” — Albert Einstein
  138. “The stock market is a device for transferring money from the impatient to the patient.” – Warren Buffett
  139. “Thousands of experts study overbought indicators, head-and-shoulder patterns, put-call ratios, the Fed’s policy on money supply…and they can’t predict markets with any useful consistency, any more than the gizzard squeezers could tell the Roman emperors when the Huns would attack.” – Peter Lynch
  140. “Investing puts money to work. The only reason to save money is to invest it.” – Grant Cardone
  141. “Formal education will make you a living; self-education will make you a fortune.” – Jim Rohn
  142. “You cannot save time for your future use however you can invest time for your future.” – John F. Heerdink, Jr. 
  143. “We always live in an uncertain world. What is certain is that the United States will go forward over time.” – Warren Buffett
  144. “Never test the depth of the river with both of your feet.” – Warren Buffet
  145. “Know what you own, and know why you own it.” – Peter Lynch
  146. “Liquidity is only there when you don’t need it.” -Old Proverb
  147. “There is no such thing as no risk. There’s only this choice of what to risk, and when to risk it.” – Nick Murray
  148. “If you want to be a millionaire, start with a billion dollars and launch a new airline.” – Richard Branson
  149. Fear incites human action far more urgently than does the impressive weight of historical evidence.” – Jeremy Siegel
  150. “In investing, what is comfortable is rarely profitable.” – Robert Arnott
  151. “Spend each day trying to be a little wiser than you were when you woke up.” – Charlie Munger
  152. “The entrance strategy is actually more important than the exit strategy.” – Edward Lampert
  153. “The rivers don’t drink their own water; Trees don’t eat their own fruits. The sun does not shine for itself, And flowers do not spread their fragrance For themselves. Living for others is a rule of nature” – PopeFrancis
  154. “It is impossible to produce superior performance unless you do something different from the majority.” – John Templeton
  155. “Inaction and patience are almost always the wisest options for investors in the stock market.” – Guy Spier
  156. “Remember that the stock market is a manic depressive.”  – Warren Buffett
  157. “An investment in knowledge pays the best interest.” – Benjamin Franklin
  158. “I believe the returns on investment in the poor are just as exciting as successes achieved in the business arena, and they are even more meaningful!” -Bill Gates
  159. “Every portfolio benefits from bonds; they provide a cushion when the stock market hits a rough patch. But avoiding stocks completely could mean your investment won’t grow any faster than the rate of inflation.” – Suze Orman
  160. “The tax on capital gains directly affects investment decisions, the mobility and flow of risk capital… the ease or difficulty experienced by new ventures in obtaining capital, and thereby the strength and potential for growth in the economy.” – John F. Kennedy
  161. “If all the economists were laid end to end, they’d never reach a conclusion.
    -George Bernard Shaw
  162. “The riskiest thing we can do is just maintain the status quo. I get up at 4:30 in the morning, seven days a week, no matter where I am in the world. I think it is important for people who are given leadership roles to assume that role immediately. What I’ve really learned over time is that optimism is a very, very important part of leadership.” – Bob Iger, Former Ceo of Disney
  163. “In the short run, the market is a voting machine. But in the long run, it is a weighing machine.” – Ben Graham
  164. “In investing, what is comfortable is rarely profitable.” -Robert Arnott
  165. “The fundamental law of investing is the uncertainty of the future.” -Peter Bernstein
  166. “How many millionaires do you know who have become wealthy by investing in savings accounts?” -Robert G Allen
  167. “Greed is all right, by the way. I think greed is healthy. You can be greedy and still feel good about yourself.”-Ivan Boesky
  168. Michael Marcus taught me one other thing that is absolutely critical: You have to be willing to make mistakes regularly; there is nothing wrong with it. Michael taught me about making your best judgment, being wrong, making your next best judgment, being wrong, making your third best judgment, and then doubling your money.” -Bruce Kovner
  169. “The policy of being too cautious is the greatest risk of all.” -Jawaharlal Nehru
  170. “I talk about macro themes a lot because they are fun to talk about, but it is the risk management that is the most important thing. The risk control is all bottom-up. I structured the business right from the get-go so that we would have lots of diversification.” -Michael Platt
  171. “Blaming speculators as a response to financial crisis goes back at least to the Greeks. It’s almost always the wrong response.” -Larry Summers

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