fbpx

YOUR GUIDE TO STAYING INFORMED IN THE MARKETS

Subscribe for FREE Email Updates & Access To EXCLUSIVE Research!

The Stock Market Spirals As The Fed Increases Pressure This Week- $CANO $SPRO $VIRT $VIX Rise!

By John F. Heerdink, Jr.
Quote of the Day:  “The essential conditions of everything you do must be choice, love, passion.” – Nadia Boulanger


Happy Saturday All!

I hope that you all had one helluva week as we have now officially pushed our way into the fall season and started the run towards the yearend holiday season. As for the stock market, it was basically a downward spiraling affair, The market was essentially seized by the Fed’s intense efforts to continue to raise interest rates to wage their war on inflation coupled with the fears of investors. In fact, the Fed confirmed the expected 75 basis point raise on Wednesday as they concluded their September 20-21 FOMC meeting, while they reminded us over and over again that they are in this inflationary fight until the very end. The Fed’s next meeting will conclude on November 2 and the federal funds rate is now believed to be moving up to approx. 4.4% by the end of the year from where it sits now in the 3% to 3.25% range. In concert, the yield curve rose accordingly and significantly again this week while increasing its inversion. The 2-yr note yield moved up 37 basis points to end at 4.21% & the 10-yr note yield rose by 15 basis points to end at 3.70%. With the Fed’s efforts and now that +6% mortgages are firmly in place, the housing market is showing increasing signs of weakness and the US and the global economy is likely headed towards a recession or already in it. On the bright side, oil prices finally moved below $80 to end at $79.43/bbl (-7.1% for the week), but unfortunately it seems to be, at least in part, because global growth is waining. The US dollar also jumped again & is now at an extreme value closing at $112.96 placing the US and multinationals at odds with the balance of the world. Around the world, we saw a number of countries, except for Japan, raise their interest rates too, which served to unsettle currencies, economies, and the markets. 

At the end of the week all major indices dropped significantly for the second consecutive week. The S&P 500 closed at 3,693.23, near the 3600 support level, down 4.6% for the week and is now down 22.5% YTD. Note that Goldman Sachs has now reduced their S&P 500 target price from 4300 to 3600 for the year and has even pointed towards a 3,150 level as a low target that could be realized in a flash sale. 11 of the 11 sectors closed in the red this week with the consumer discretionary sector taking the biggest hit falling 9.0%. The Dow closed lower at 29,590.41 and down 4.0% for the week and is now down 18.6% YTD.  The Nasdaq closed at 10,867.93 and down 5.1% weekly & is now down 30.5% YTD.  With the overall negative sentiment seen across the major indices, the CBOE Volatility Index (^VIX) closed sharply higher at $29.92, +13.76% over the last 5-days and now up ~29% over the last 10-days. The small caps on the Russell 2000 closed at 1,676.71 and down 6.8% for the week & is now down 25.5% YTD. The MicroCaps also moved down sharply as the iShares Micro-Cap ETF (IWC) closed at $103.49, -7.13% over the last 5-days and is now down 25.94% YTD.  

THE MAC REPORTS

On Monday, the September NAHB Housing Market Index report confirmed a mark at 46 showing a further dip below the Mendoza line (50) and exhibiting that confidence took a further hit.

On Tuesday, the August Housing Starts and Building Permits report confirmed that housing starts came in totaling 1.575M in August & building permits in August clocked in lower at 1.517M.

On Wednesday, the weekly MBA Mortgage Applications Index report confirmed a 3.8% increase. However, the existing home sales report showed a .4% M/M decline in August to a seasonally adjusted annual rate of 4.80M. Existing how sales have now dropped for 7 consecutive months and now total sales in August are 19.9% Y/Y. The weekly EIA Crude Oil Inventories report also confirmed a 1.14M barrel build.

On Thursday, the initial claims report for the week ending September 17 showed a rise of 5k to 213k, while continuing jobless claims fell by 22k to 1.379M. The Q2 Current Account Deficit report showed an improvement to -$251.5B
The August Leading Economic Index report also showed a .3% drop M/M.

On Friday, the preliminary September IHS Markit Manufacturing PMI reading report clocked slightly higher at 51.8, while the IHS Markit Services PMI reading came in as expected at 43.7 .

BIOTECH AND HEALTHCARE

The biotech sector moved significantly lower this week, however more acquisitions, reverse mergers, & licensing deals surfaced as this sector continues to churn through the wreckage that it has created and is finding light on the other side. The Nasdaq Biotechnology ETF (IBB) closed at $115.32, -6.21% over the last 5-days, & is down -24.44% YTD. The NYSE ARCA Biotech Index (^BTK) closed at 4,750.80, -4.38% over the last 5-days. The SPDR S&P Biotech ETF (XBI) closed at $83.27, 5.39% over the last 5-days & is now down 25.63% YTD. The 52-week range is is now $61.78-$134.79.

As an example of progress in the face, shares of Spero Therapeutics (SPRO), a multi-asset, clinical-stage biopharmaceutical company focused on identifying, developing, and commercializing novel treatments for bacterial infections, including multi-drug resistant bacterial infections and rare diseases, surged to a close of $1.97, +118.89% over the last 5-days.  The majority of the move came after GSK (GSK) announced that they had entered into an exclusive license agreement for Spero’s late-stage antibiotic asset, tebipenem HBr. Tebipenem HBr is being developed as the first oral carbapenem antibiotic for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis, caused by certain bacteria. GSK is licensing the drug for an upfront payment of $66 million and with milestones the deal could be worth to $291 million. In connection with the license agreement and pursuant to a stock purchase agreement between GSK and Spero, GSK has agreed to make a $9 million common stock investment in Spero, purchasing 7,450,000 shares of Spero’s common stock at a purchase price of approximately $1.20805 per share, not to exceed 19.99% beneficial ownership of Spero by GSK and its affiliates.

Shares of Cano Health (CANO), a leading value-based a high-touch, technology-powered healthcare primary care provider and population health company, rose 33.58% over the last 5-days as Humana and CVS are reportedly interested in acquiring them.

EV, TECH, CONSUMER, FINANCIALS


Apple (AAPL) closed at $150.43, -.18% over the last 5-days. Apple enjoys a 6.82% weighting in the S&P 500. Apple’s iPhone 14 hit stores on Friday the 16th. 

On Sept. 7, Apple  introduced Apple Watch® Series 8 and the new Apple Watch SE®, which bring groundbreaking technology and performance, and important safety innovations to the two best-selling smartwatches. Apple Watch Series 8 features the beloved design of Apple Watch, including a large, Always-On Retina® display and a strong crack-resistant front crystal. With all-day 18-hour battery life, Apple Watch Series 8 builds on best-in-class health and safety features like the ECG app and fall detection by introducing temperature-sensing capabilities, retrospective ovulation estimates, Crash Detection, and international roaming. The new Apple Watch SE delivers the core Apple Watch experience, including Activity tracking, high and low heart rate notifications, and Emergency SOS, as well as the new Crash Detection feature and a completely redesigned back case that perfectly matches the three classic case finishes, all at a more affordable price of $249 (US). Both models are powered by watchOS® 9, introducing new and more customizable watch faces like Lunar and Metropolitan, an enhanced Workout app, sleep stages, a first-of-its-kind AFib History feature, and an all-new Medications app. Apple Watch Series 8 and Apple Watch SE are available to order today, with availability beginning Friday, September 16. Jeff Williams, Apple’s chief operating officer “We hear from customers how Apple Watch helps them stay connected with loved ones, be more active, and live healthier lives. Apple Watch Series 8 reinforces our commitment in these areas with the addition of pioneering technology, while Apple Watch SE brings advanced core features at a new starting price. Powered by watchOS 9, the best smartwatches deliver more capabilities than ever before.”

 On Aug. 1, reportedly Apple raised $5.5B by issuing of 4 series of bonds with ratings of AAA from Moody’s Investors Service and AA+ from S&P Global, according to Informa Global Markets.

On July 28th,  Apple announced financial results for its fiscal 2022 third quarter ended June 25, 2022. The Company posted a June quarter revenue record of $83.0 billion, up 2 percent year over year, and quarterly earnings per diluted share of $1.20. Tim Cook, Apple’s CEO stated, “This quarter’s record results speak to Apple’s constant efforts to innovate, to advance new possibilities, and to enrich the lives of our customers. As always, we are leading with our values, and expressing them in everything we build, from new features that are designed to protect user privacy and security, to tools that will enhance accessibility, part of our longstanding commitment to create products for everyone.”  Luca Maestri, Apple’s CFO stated, “Our June quarter results continued to demonstrate our ability to manage our business effectively despite the challenging operating environment. We set a June quarter revenue record and our installed base of active devices reached an all-time high in every geographic segment and product category. During the quarter, we generated nearly $23 billion in operating cash flow, returned over $28 billion to our shareholders, and continued to invest in our long-term growth plans.” Apple’s board of directors has also declared a cash dividend of $0.23 per share of the Company’s common stock. The dividend is payable on August 11, 2022 to shareholders of record as of the close of business on August 8, 2022.

tesla

EV giant Tesla (TSLA) closed at $275.33, -9.24% over the last 5-days after recently splitting their stock 3- 1. On Sept. 22, Barron’s reported that a Tesla recall affecting 1,096,762 vehicles showed up on the National Highway Traffic Safety Administration, or NHTSA, website. The recall is for a safety issue. A glitch in the power window operating system.

Reportedly, Elon Musk accused Twitter Inc. (TWTR) of fraud by concealing serious flaws in the social media company’s data security, which the entrepreneur said should allow him to end his $44 billion deal for the company, according to a Thursday court filing.

On Friday September 9th, Elon Musk tweeted, “A major Fed rate hike risks deflation.” Bloomberg also reported that Elon stated that the global economy is “past peak inflation.”

Recently, it was widely reported that Tesla has plans for expanding its Travis County, Texas campus for its brain-computer interface startup Neuralink & a possibly a lithium battery plant.

On September 1, it was reported that Tesla sold 77k China-made cars last month, the China Passenger Car Association (CPCA) said Thursday, a 74% increase over the same period last year. 
 
Recently, Tesla CEO Elon Musk stated that the company is targeting the end of 2022 to have  self-driving technology available for consumption in the US a& European markets, with a caveat that regulatory approvals will rule ultimately.

On Aug. 25, it was widely reported that California has approved, via the California Air Resources Board (CARB), a requirement for automakers to only sell new electric & certain hybrids in CA state by 2035.

On Aug. 1,  Bloomberg reported that Indonesian President Joko Widodo has urged electric vehicle (EV) maker Tesla to manufacture its cars, as well as batteries, in the country.

 
Tesla’s shareholders of record on Aug. 17, will receive a dividend of 2 new shares for each held after the close of trading on Aug. 24 and the stock will trade at the new, split-adjusted, price the next day, Aug. 25, thus completing its planned 3for 1 stock split.
Tesla reported its Q2 earnings after the close on July 19, meeting analysts’ estimates. Tesla stated that it sold 75% of its Bitcoin, turning it into fiat currency, adding $936 in cash to its balance sheet, but they also ended their streak of reporting record revenue. Revenue came in at $16.9 billion vs $16.88 billion expected & Adjusted EPS: $2.27 vs $1.83 expected. Tesla still expects to see 50% annual growth in their vehicle deliveries. Tesla CEO Elon Musk believes thinks that inflation has likely peaked, he stated “If I were to guess — and I would take this with a grain of salt — I think inflation will decline towards the end of this year. We are certainly seeing prices of commodities trending lower.”
 
 
 
 
Shares of ADT Inc. (ADT), the most trusted brand in smart home and small business security, closed at $7.70, -5.75% over the last 5-days.
 
On Tuesday, Sept 6, ADT and State Farm, the 100-year good neighbor and largest insurer of homes in the U.S. with 13.7 million homeowners policies in force, announced that State Farm will make a $1.2 billion equity investment in ADT, resulting in State Farm owning approximately 15% of ADT after the equity investment and the tender offer (described below) close. Additionally, ADT plans to partner with State Farm, and build upon its existing relationship with Google, with the aim to expand opportunities to combine next-generation security, innovative smart home technology and reimagined risk-mitigation capabilities to monitor, detect, prevent and optimize against homeownership risks. State Farm will commit up to $300 million to fund product and technology innovation, customer growth and marketing. In addition, Google has separately agreed to commit an incremental $150 million, subject to the achievement of certain milestones, to advance opportunities created by this type of innovation, raising its total success fund commitment to $300 million. Jim DeVries, ADT President and CEO stated, “ADT’s partnership with State Farm creates the capability to drive innovation in homeowners insurance on a broad scale. By delivering a truly connected home, together we can improve the customer experience and provide more peace of mind. These new and expanded partnerships represent another bold step forward for our company and provide ADT more avenues to grow our customer base, strengthen brand loyalty and lower customer acquisition costs.”


Shares of JPMorgan (JPM) closed at $109.24, -6.78% over the last 5-days. On Sept. 20, JPM declared a quarterly dividend of $1.00 per share on the outstanding shares of the common stock of JPMorgan Chase. The dividend is payable on October 31, 2022, to stockholders of record at the close of business on October 6, 2022.

On September 11, J.P. Morgan announced that it has signed an agreement to acquire Renovite Technologies, Inc. (Renovite), a leading cloud-native payments technology company. The strategic acquisition of Renovite will help J.P. Morgan Payments build its next-generation merchant acquiring platform, bolster the firm’s payments modernization strategy and support its journey to the cloud. Upon closing of the transaction, Renovite will become part of J.P. Morgan Payments, which combines corporate treasury services, trade finance, card and merchant services capabilities at the firm, delivering an integrated payments experience to clients across the economy.

On September 7, J.P. Morgan announced that Paul Halpern has joined as Chief Marketing Officer for U.S. Wealth Management, one of the firm’s top areas of focus for customer growth. Halpern will lead an extensive team at a crucial time when the business is set to launch multiple new products later this year.

This week, the SEC decided not to ban payment order flow deals. Shares of Virtu Financial (VIRT), a leading provider of financial services and products that leverages cutting edge technology to deliver innovative, transparent trading solutions to its clients and liquidity to the global markets, moved higher to close at $22.71, +3.51% over the last 5-days.


Amazon.com, Inc. (NASDAQ: AMZN) $113.78, -7.89% over the last 5-days. On September 21, Amazon (NASDAQ: AMZN) announced that it is expanding its renewable energy portfolio globally, with an additional 2.7 gigawatts (GW) of clean energy capacity across 71 new renewable energy projects. This includes the company’s first renewable energy project in South America—a solar farm in Brazil—and its first solar farms in India and Poland. Once fully operational, Amazon’s global renewable energy portfolio will generate 50,000 gigawatt hours (GWh) of clean energy, which is the equivalent amount of electricity needed to power 4.6 million U.S. homes each year.

Shares of Microsoft Corp. (MSFT) closed at $237.92, -2.79% over the last 5-days. On Sept. 22, Microsoft Corp., Planet Labs PBC and The Nature Conservancy on Thursday announced its plans to launch the Global Renewables Watch (GRW), a first-of-its-kind living atlas intended to map and measure all utility-scale solar and wind installations on Earth using artificial intelligence (AI) and satellite imagery, allowing users to evaluate clean energy transition progress and track trends over time.

Shares of Salesforce, Inc. (CRM) closed at $151.51, -6.81% over the last five days. On September 21, Salesforce announced the appointment of Robin Washington as Lead Independent Director of the Company’s Board of Directors, effective September 15, 2022. Washington, who also chairs the Board’s Audit Committee, succeeds Sanford Robertson, who will continue to serve as a Director and Chair of the Nominating and Corporate Governance Committee.

Shares of NVIDIA (NVDA), a pioneer in accelerated computing, closed at $131.98, -8.26% over the last 5-days. On Sept, 20, NVIDIA announced the second generation of NVIDIA OVX™, powered by the NVIDIA Ada Lovelace GPU architecture and enhanced networking technology, to deliver groundbreaking real-time graphics, AI and digital twin simulation capabilities. The new NVIDIA OVX systems are designed to build 3D virtual worlds using leading 3D software applications and to operate immersive digital twin simulations in NVIDIA Omniverse™ Enterprise — a scalable, end-to-end platform enabling enterprises to build and operate metaverse applications.

Cathie Wood’s ARK Innovation ETF (ARKK) closed at $37.83, -11.16% over the last 5-days. 

The Technology Select Sector SPDR Fund (XLK) closed at $123.74, -3.86% over the last 5-days.


Walt Disney Company (DIS) closed at $99.50, -8.08% over the last 5-days. Disney announced that it is axing its Disney Infinity series of video games & resulted in a $147m write-off.

On September 1, it was announced that Walt Disney’s Grumman Gulfstream I plane is making a cross-country journey to Anaheim, California, where it will be on display for fans attending the sold-out D23 Expo 2022 presented by Visa from September 9 through 11. D23 and the Walt Disney Archives, along with D23 Expo Platinum sponsor Amazon, have restored the plane’s exterior for guests to see in a specially curated exhibit in the Arena of the Anaheim Convention Center called Mickey Mouse One: Walt’s Plane presented by Amazon. The exhibit will highlight the history of the plane—also known as “The Mouse”—and showcase its significance in The Walt Disney Company’s history. In 1963, Walt Disney acquired the iconic Gulfstream that would come to be known as “The Mouse.” The interior of the plane, initially designed with creative input from Walt and his wife, Lillian, seated up to 15 passengers and included a galley kitchen, two restrooms, two couches, a desk, and nods to the mouse who started it all, including matchbooks and stationery adorned with a silhouette of Mickey Mouse. Mickey’s initials were eventually included in the tail number of the plane, too, as N234MM, in 1967. Throughout its 28 years of service to The Walt Disney Company, the plane flew 20,000 hours and transported an estimated 83,000 passengers before it was grounded.

On Aug. 15th, a report surfaced that Dan Loeb’s Third Point Capital had built a position and was negotiating for ESPN to be rolled out. Here’s Disney’s response.

Recently, Disney reported its fiscal Q3 results recently that beat Wall Street’s expectations. In the report, Disney highlighted the following: Revenues for the quarter and nine months grew 26% and 28%, respectively, Diluted earnings per share (EPS) from continuing operations for the quarter increased to $0.77 from $0.50 in the prior-year quarter. Excluding certain items, diluted EPS for the quarter increased to $1.09 from $0.80 in the prior-year quarter, Diluted EPS from continuing operations for the nine months ended July 2, 2022 increased to $1.66 from $1.02 in the prior-year period. Excluding certain items(1), diluted EPS for the nine months increased to $3.22 from $1.91 in the prior-year period. Bob Chapek, Chief Executive Officer, The Walt Disney Company stated, “We had an excellent quarter, with our world-class creative and business teams powering outstanding performance at our domestic theme parks, big increases in live-sports viewership, and significant subscriber growth at our streaming services. With 14.4 million Disney+ subscribers added in the fiscal third quarter, we now have 221 million total subscriptions across our streaming offerings. We continue to transform entertainment as we near our second century, with compelling new storytelling across our many platforms and unique immersive physical experiences that exceed guest expectations, all of which are reflected in our strong operating results this quarter.”

Shares of McDonald’s (MCD) closed at $245.95, -3.51% over the last 5-days. On September 14, McDonald’s Corporation is announcing the establishment of a new facility, Speedee Labs, which will be focused on driving the customer experience and supporting restaurant teams through innovation, at its global headquarters (MHQ) located at 110 N. Carpenter Street in Chicago’s West Loop neighborhood. An example of McDonald’s commitment to the city of Chicago, this new facility will bring teams from McDonald’s corporate office and the existing Innovation Center (IC) in Romeoville, IL together in a new innovative environment creating more opportunities for collaboration and end-to-end development of restaurant solutions and technologies. Introduced in 1948, McDonald’s Speedee Service System revolutionized the way a restaurant could operate. New kitchen processes streamlined crew responsibilities, making it easier than ever to serve customers efficiently. Now, through Speedee Labs, McDonald’s will continue to define tomorrow’s restaurant solutions.


GOLD & SILVER

Gold prices closed at $1,647/oz., -$32/oz. & silver prices closed at $18.92/oz., +$.70/oz. for the week.

Hecla Mining (HL) closed at $3.63, -9.48% over the last 5-days & First Majestic (AG) closed at $6.73, -12.26% over the last 5-days. 

On Sept. 7,  Hecla Mining Company and Alexco Resource Corp. (NYSE American:AXU; TSX:AXU) announced that the Alexco acquisition has been completed.


MEMES CENTRAL

AMC Entertainment (AMC) closed at $7.99, -11.02% over the last 5-days. On Aug. 25, Fathom Events, owned by AMC Entertainment Inc. (NYSE: AMC); Cinemark Holdings, Inc. (NYSE: CNK); and Regal, a subsidiary of the Cineworld Group (LSE: CINE.L) and Sonovision announced the release of the new documentary film SAINT MICHAEL: MEET THE ANGEL in theaters for one-night-only on Thursday, September 29.  On August 4, AMC Entertainment reported results for the second quarter ended June 30, 2022.  Total revenues grew to $1,166.4 million compared to $444.7 million for the second quarter of 2021.

GameStop (GME) closed at $25.04, -12.57% over the last 5-days. On Sept 7th, GameStop released financial results for the second quarter ended July 30, 2022. Net sales were $1.136 billion for the quarter, compared to $1.183 billion in the prior year’s second quarter. Sales attributable to collectibles, which is a segment the Company intends to grow over the long-term, were $223.2 million for the quarter, compared to $177.2 million in the prior year’s second quarter. Selling, general and administrative expenses were $387.5 million for the quarter, representing a sequential decline of 14.3% from the first quarter of 2022 and reflecting, in part, the Company’s focus on right-sizing costs following a period of significant investment in long-term initiatives. After the close today, September 7, GameStop Corp. also announced that it has entered into a partnership with FTX US (“FTX”). The partnership is intended to introduce more GameStop customers to FTX’s community and its marketplaces for digital assets. In addition to collaborating with FTX on new ecommerce and online marketing initiatives, GameStop will begin carrying FTX gift cards in select stores. During the term of the partnership, GameStop will be FTX’s preferred retail partner in the United States. The financial terms of the partnership are not being disclosed.

Seanergy Maritime Holdings Corp. (NASDAQ: SHIP) closed at $.575, -2.27% over the last 5-days. On Aug. 4, Seanergy Maritime Reported Record Financial Results for the Second Quarter and Six Months Ended June 30, 2022 and declare a dividend of $0.025 Per Share.


CRYPTO & BITCOIN

Bitcoin (BTC) closed at $18,921.47, -3.19% over the last 5-days. 

ENERGY

The Energy Select Sector SPDR Fund or ETF (XLE) closed at $70.48, -10.15% over the last 5-days. Chevron (CVX) closed at $144.77, -7.47% over the last 5-days.

Oil prices closed down by 4.86% on Friday to end at $79.43/bbl.


NEXT WEEK



On Monday the stock market will be closed to observe Labor Day in the US and then we will have 4 normal trading days thereafter.

VP WATCHLIST UPDATES

Please review our complete VP Watchlist that includes Apple (AAPL), Disney (DIS), Tesla (TSLA) & a select group of emerging names.  The pages will allow you to learn more and keep up with these companies daily.

For now, please see the summaries  from the VP Watchlist below:

  • Shares of Natural-Killer cell (NKcell) focused biopharmaceutical firm Fate Therapeutics (FATE) closed at $21.97, -12.12% over the last 5-days. 
    • On Aug. 8, Fate Therapeutics announced the publication of preclinical study results demonstrating the successful generation, durable anti-tumor response, and functional persistence of TCR-CAR+ iPSC-derived CD8αβ T cells from induced pluripotent stem cells (iPSCs). The CD8αβ T cells were derived from a single engineered iPSC integrating a novel chimeric antigen receptor (CAR) transgene into the T-cell receptor alpha constant (TRAC) locus, ensuring complete bi-allelic disruption of T-cell receptor (TCR) expression and promoting uniform CAR expression. The discoveries were made under a multi-year research collaboration between the Company and Memorial Sloan Kettering Cancer Center (MSK) led by Michel Sadelain, M.D., Ph.D., Director, Center for Cell Engineering and Head, Gene Expression and Gene Transfer Laboratory, and were published this week in Nature Biomedical Engineering.
    • After the market closed on August 3, Fate released its business highlights and financial results for the second quarter ended June 30, 2022. Scott Wolchko, President and Chief Executive Officer of Fate Therapeutics stated,  “We continue to make important strides across our clinical, regulatory, and manufacturing operations to support pivotal readiness of our iPSC-derived NK cell product candidates for B-cell lymphoma, and are looking forward to meeting with the FDA in the third quarter to discuss registrational pathways for the treatment of relapsed / refractory aggressive lymphomas, including for patients that have previously failed CD19-targeted CAR T-cell therapy. We are also excited that clinical investigation of FT536 has initiated to assess the targeting of oncogenic and cellular stress ligands, a novel pan-tumor-targeting strategy with the potential to overcome common mechanisms of tumor escape that frequently emerge in patients with advanced solid tumors. Finally, we continue to drive our collaborations with Janssen and Ono with strong momentum, and are well positioned to achieve significant milestones and advance three multiplexed-engineered, CAR-targeted cell collaboration candidates into clinical development over the next 12 months.”
  •  


  • Shares of Atossa Therapeutics, Inc. (Nasdaq: ATOS), a clinical-stage biopharmaceutical company seeking to discover and develop innovative medicines in areas of significant unmet medical need with a current focus on breast cancer and COVID-19, closed at $.8243, -11.37% over the last 5-days.
    • Atossa Therapeutics’ Kyle Guse, General Counsel & Chief Financial Officer attended the 24th Annual H.C. Wainwright Global Investment Conference that was  held on September 12 – 14, 2022 at the Lotte New York Palace.  
 
 
On Aug. 25th, Atossa’s CEO, Dr. Steven Quay, M.D., Ph.D., and Kyle Guse, GC & CFO presented at Tribe Public’s Webinar Presentation and Q&A Event. During this complimentary event, Atossa management spoke of new opportunities for its inhalation therapy, AT-H201, to potentially treat lung injury caused by cancer treatment and were available for a Q&A session focused on Atossa’s research programs and future development. To watch the event video titled The Important Role For Inhalation Therapy In Oncology” please visit the Tribe Public YouTube Channel. 
    • On Aug. 8, Atossa announced their financial results for the fiscal quarter ended June 30, 2022, and provided an update on recent company developments. Dr. Steven Quay, Atossa’s President and Chief Executive Officer stated, “We continue to make steady progress with our Endoxifen programs: one to reduce tumor cell activity in breast cancer patients in the neoadjuvant setting; and another to reduce dense breast tissue in women. Our work on AT-H201 demonstrated valuable outcomes, not the least of which was an understanding of how to pursue its development in the field of oncology. With the widespread availability of SARS-CoV-2 vaccines and other therapies now approved to treat COVID-19, we believe that altering the development pathways for AT-H201 in cancer patients with compromised lung-function resulting from radiation treatment may fill a compelling unmet medical need and create additional value for our stockholders. Lung injury caused by radiation treatment affects 30-40% of lung cancer patients, and ~35% of esophageal cancer patients. In non-small cell cancer patients receiving concurrent chemotherapy and radiation therapy the incidence of lung injury is estimated to be greater than 60%. As we previously announced, rather than proceeding with Part D of the AT-H201 study in COVID-19 patients, we plan to quickly initiate a clinical study of patients with compromised lung function caused by radiation treatment and we anticipate announcing next steps in the coming months.”
    • July 28, Atossa announced it has completed dosing participants in Part C of its Phase 1/2a clinical study of its proprietary inhalation therapy (or, AT-H201) in Australia. AT-H201 consists of two drugs previously approved by the FDA to treat other diseases. AT-H201 is intended to be inhaled via nebulizer with the goal of preventing or reducing lung injury that may be caused by fibrin deposition, fluid build-up and secondary infection. Part C of the study involved administering the two drugs in succession in healthy volunteers. The study originally included a Part D which was designed to assess the effects of the treatment regimen in hospitalized COVID-19 patients with moderate illness. However, due to the rapidly shifting COVID-19 treatment landscape and the introduction of effective vaccines limiting hospitalizations, Atossa has evaluated indications for AT-H201 beyond COVID-19 patients, including treating and/or preventing lung injury in patients undergoing certain cancer treatments. Rather than conducting Part D of the Phase 1/2a clinical study, Atossa now plans to shift the development of AT-H201 to closely align with its oncology focus by continuing the development in patients with compromised lung-function due to the damaging effects of cancer treatment. For example, radiation treatment can lead to radiation induced lung injury, which is poorly treated with current therapies and is often irreversible. Furthermore, radiation damage can limit the overall success of lung cancer treatment leading to a reduction in efficacy and poor disease control. AT-H201 has pharmacological properties to potentially curtail excessive radiation-induced lung injury without compromising standard of care cancer therapy for cancer patients. AT-H201 is designed to prevent and reduce dose-limiting toxicities, and enable a more durable therapeutic tumor response for cancer patients receiving pulmonary radiation. Steven Quay, M.D., Ph.D., CEO and President of Atossa stated, “We are happy to have completed Parts A, B and C of the clinical trial and look forward to evaluating the results. With widespread availability of SARS-CoV-2 vaccines and other therapies now approved to treat COVID-19, we believe that altering the development pathways for AT-H201 in patients with compromised lung-function resulting from radiation may fill a compelling unmet medical need and create more value for our stockholders. Based on our work to date with AT-H201, we believe we can quickly initiate a clinical study in this setting and we plan to announce our next steps in the fourth quarter.”
    • On July 28,  Jason McCarthy Ph.D., a biotech analyst at the Maxim Group, put out a note reconfirming his BUY rating and a $4 target price on Atossa.
  •  


  • Shares INVO Bioscience (NASDAQ: INVO), a medical device company focused on creating alternative treatments for patients diagnosed with infertility and developers of INVOcell®, the world’s only in vivo Intravaginal Culture System, closed at $1.07/share. The 52-wk range is $.63 – $4.28.
    • On Aug. 25th, INVO Bioscience announced that Advanced Reproductive Centre, Hospital Canselor Tuanku Muhriz (HCTM), formally known as Hospital Universiti Kebangsaan Malaysia (HUKM), based in Kuala Lumpur, Malaysia, is making IVC available for their patients. The move follows the successful completion of the first IVC case in the country recently with data presented at the Obstetrical and Gynecological Society of Malaysia (“OGSM”) where it was awarded a prize as a new and innovative fertility treatment. A signing ceremony announcing the launch of IVC was witnessed by the Minister of Science and Innovation and Deputy Secretary General. HCTM, one of the five university hospitals in Malaysia, is currently the highest volume fertility center in the country. Steve Shum, CEO of INVO Bioscience, commented, “We are excited that INVOcell will officially be commercialized at HCTM in Kuala Lumpur following the successful presentation of data at OGSM and government support by the Minister of Science and Innovation and Deputy Secretary General. HCTM will start offering IVC both in their public and private sectors with an expectation to complete a number of cycles by the end of 2022. We are also working with partners in Malaysia to open up an INVO Centers in their existing practice as we strive to bring our innovative advanced fertility treatment to the people of Malaysia.”
    • INVO Bioscience reported financial results for its second quarter 2022, ended June 30, 2022, after the market close on Monday, August 15, 2022.  INVO highlighted the following progress: Existing INVO Centers experienced a 20% increase in patient inquiries and consultations compared to the first quarter of 2022, as key activities continue to build, Progressing toward planned openings of additional INVO Centers in Tampa, Florida, Kansas City, Kansas, and the San Francisco Bay Area, In May 2022, signed an exclusive distribution agreement with Onesky Holdings Limited (“Onesky”) for mainland China (excludes Hong Kong, Macau and Taiwan). Onesky will be responsible for registering the product in the country, and upon government approval, will be obligated to purchase minimum quantities of INVOcell totaling approximately $14 million over the subsequent five-year term, & increased U.S.-based expansion opportunities post-Ferring, including both greenfield INVO Centers and potential acquisitions of established fertility clinics.
  •  
  •  



  • Shares of InMed Pharmaceuticals, Inc. (NASDAQ: INM), a leading clinical-stage pharmaceutical company developing cannabinoid-based drug candidates for high unmet medical needs and IntegraSyn, a proprietary and cost effective manufacturing approach for synthesized rare cannabinoids, closed at $5.57/share after recently reverse splitting 25-1.  Please visit the INM page at our website to learn more and check out the videos section too. 
    • After the close, September 13, InMed announced the closing of its previously announced private placement with two healthcare-focused institutional investors for the issuance and sale of 691,245 of its common shares at a purchase price of $8.68 per share (or pre-funded warrant in lieu thereof) priced at-the-market under Nasdaq rules. In addition, the Company has issued to the investors in the offering unregistered preferred investment options to purchase up to an aggregate of 1,382,490 common shares.The aggregate gross proceeds to the Company from the private placement were approximately $6 million. The Company intends to use the net proceeds from the offering to continue pipeline development of its pharmaceutical drug candidates, advance manufacturing know-how of cannabinoids and cannabinoid analogs, support intellectual property development and other commercial activities, and for general working capital purposes. H.C. Wainwright & Co. acted as the exclusive placement agent for the offering. The unregistered investment options issued in the offering are exercisable immediately upon issuance at an exercise price of $8.44 per share and will expire seven years from the date of issuance. In addition, an investor in the private placement agreed to cancel preferred investment options to purchase up to an aggregate of 412,331 common shares of the Company which were previously issued to the investor.

    • On Sept. 8, InMed announces an update on its research/development and commercial activities. Eric A. Adams, InMed CEO, stated, “The Company continues to execute on its research and development (“R&D”) plans to complete enrollment in a Phase 2 clinical program in epidermolysis bullosa (“EB”) by calendar year end, to continue to advance a preclinical drug candidate in ocular disease and to investigate the utility of proprietary cannabinoid analogs in targeting specific diseases. We remain enthusiastic with the potential of the proprietary cannabinoid analog program that resulted in part from our acquisition of BayMedica, LLC (“BayMedica”) in October 2021. However, despite the significant efforts by the commercial team at BayMedica, the market demand for the BayMedica naturally-occurring cannabinoids in the Health & Wellness (“H&W”) sector is not progressing as anticipated.” READ MORE. 
    • On Aug. 9, InMed announced the appointment of Nicole Lemerond to its Board of Directors, effective immediately. Nicole Lemerond is a financial executive with over 25 years of experience in investment management, private equity, investment banking and leveraged finance. She has significant experience executing complex transactions, managing diligence processes, raising capital and structuring balance sheets. Throughout her career, Ms. Lemerond has worked with public and private company management teams and boards to increase stakeholder value. She established and led healthcare groups at leading investment firms and has also worked at several large financial institutions, including Lehman Brothers and The Carlyle Group. Ms. Lemerond holds a Bachelor of Science degree from Cornell University and is a CFA charterholder. Contemporaneous with Ms. Lemerond’s appointment, Adam Cutler has decided to transition off the Board of Directors. Mr. Cutler has served on the Board since 2015, during which time his financial and healthcare expertise has been instrumental in advancing the strategic initiatives of the Company. Over the years, Mr. Cutler has served as Chair of the Audit Committee as well as a member Governance and Nomination Committee. Ms. Lemerond will replace Mr. Cutler as a member of the Audit Committee and as a member of the Governance and Nomination Committee.
    • On July 18, InMed announced Michael Woudenberg has been appointed Chief Operating Officer of the Company, overseeing all day-to-day operations. Mr. Woudenberg was previously Senior Vice President of Chemistry, Manufacturing and Controls. Mike has been an integral part of the executive team for the last four years, supporting multiple functions within the organisation. Prior to joining InMed, Mike had over 20 years of successful drug development, process engineering, GMP manufacturing and general management experience at all levels of various companies. Mike’s intimate knowledge of the Company’s operations and extensive leadership experience make him an ideal candidate to oversee operations and support the long-term strategic growth of the Company. He will continue to report to Eric A. Adams, InMed President and CEO.


Shares of Chinook Therapeutics, Inc. (KDNY), a biopharmaceutical company focused on the discovery, development and commercialization of precision medicines for kidney diseases, closed at $18.99. 

On Aug. 8, Chinook provided a business update and reported financial results for the quarter and six months ended June 30, 2022. “During the second quarter of 2022, we executed well on advancing our pipeline of clinical and preclinical programs for rare, severe chronic kidney diseases. We continue to ramp up enrollment of patients in the phase 3 ALIGN trial for atrasentan, and the data we presented at ERA from the ongoing phase 2 AFFINITY trial of atrasentan demonstrated consistent and clinically meaningful proteinuria reductions in patients with IgAN,” said Eric Dobmeier, president and chief executive officer of Chinook Therapeutics. “For BION-1301, the additional data presented at ERA from the ongoing phase 1/2 trial reaffirms its disease-modifying potential in IgAN by demonstrating durable reductions in mechanistic biomarkers and corresponding impressive proteinuria reductions. We look forward to advancing BION-1301 into a phase 3 study for patients with IgAN in 2023. We are also continuing to make progress with dose escalation in the ongoing phase 1 trial of CHK-336 in healthy volunteers and expect to report data in the first half of 2023.”



Borqs Technologies, Inc. (Nasdaq: BRQS, $.9018), a global provider of 5G wireless solutions, Internet of Things (IoT) solutions, and innovative clean energy, recently provided the following updates on the Company.

  • On Sept 20, Borqs announced its solar energy storage subsidiary, Holu Hou Energy LLC (HHE), a company that offers state-of-the-art renewable energy and energy storage systems to the Single-Family Residential, Multi-Dwelling Unit Residential and Commercial building markets, has signed a power purchase agreement (PPA) with Kapolei Diversified Properties, LLC to deliver energy to Luhauola, a new mixed-use development in Kapolei, on the island of Oahu, Hawaii. The property includes 10,000 square feet of commercial space, plus outdoor dining for local food establishments. The residential portion of the property includes 29 workforce housing rental apartments. U.S. Energy Information Administration data shows oil generated about two-thirds of Hawaii’s electricity in 2021. That makes Hawaii the most petroleum-dependent state.

    • Holu Hou Energy will construct the Solar + Energy Storage system utilizing its market leading HoluPower Residential Energy Storage System, combined with the Residential and Commercial scale solar generation. The contract is valued at several million dollars and includes 200KW of PV and 500KWh of energy storage. The system will be placed into service in 2023.

      “Our products and services are improving the lives of customers every day by delivering cheaper, cleaner and more reliable electricity, including to those living in Multi-Dwelling Unit residential housing,” stated Brad Hansen, CEO of Holu Hou Energy. “We look forward to building on our Hawaii leadership position and bringing this same energy independence to markets like California in the near future. The cost of utility electricity in Hawaii has risen by about 60% over the last 18-months, with residential rates being at a historical high of around $0.50/kWh. Reliance on fuel oil for a significant part of Hawaii’s power generation means that these unprecedented rates are not likely to abate soon. HHE brings the most safe and productive solar and energy storage solutions to customers, including to those in income brackets not historically able to have their energy needs met by renewables.”


  • On July 15, Borqs Technologies announced that its majority owned solar energy storage systems subsidiary, Holu Hou Energy LLC (“HHE”), has signed agreement with Honokea Villages to deliver a major renewable energy generation and storage system to Honokea’s planned ecological sports training and Hawaiian Cultural facility in their “ahupua’a”, or local community. The development will have Olympic calibre training facilities for surfing, sport climbing, kayaking, beach volleyball, and more, and will serve as tool to celebrate athletics in Hawaii. The renewable energy system will feature over 3 MW of PV generation and over 4 MWh of energy storage, enough to power 100% of the operations of the facility, and will be financed under a 20-year power purchase agreement, or PPA. The system provided by HHE will begin construction in 2023 and its value is estimated at nearly $20M. This project is included in the $49.8 million of Q2 2022 signed contracts announced earlier this month. Honokea Villages was co-founded by Brian Keaulana in 2011 to address the need for Hawaiian Surf Culture to be incorporated into, what was at the time, the fledgling surf park industry. Now 11 years later there are 100+ surf parks being planned around the world with names like Kelly Slater and in places as foreign as Switzerland. “Honokea aims to ensure Hawaiian Culture is incorporated into every aspect of the planning of the family destination: excellence in sports, sustainability, arts and culture. It’s a place for the whole family that’s truly designed to benefit our community in as many ways as possible especially on our side of the island,” says Keaulana.
  • HHE is a premier provider of an energy storage system that is engineered to provide a new level of resilience to homeowner, multi-dwelling units and businesses, giving energy security in uncertain and unstable times. The Holu system is completely integrated, meaning engineered and tested from the start, at the system level. Other suppliers piece together components made by multiple vendors in unknown factories with unknown work conditions, causing the customer to have questionable reliability, safety and performance when all the disparate pieces are put together. Our energy storage system is certified and warrantied as an integrated product, including our breakthrough “modular energy controller”, so you get resilience, safety and performance you can count on day in and day out, and you get “cloud-based” upgrades and performance enhancements based upon the rate structures you reside in.



Thanks again for your attention this week. Please continue to share your thoughts, questions, & ideas as we move forward. 

In the meantime, please enjoy the balance of the weekly newsletter’s videos, quotes, updates and let’s find ways to crush it again this year!

Investing & Inspiration

  1. “The essential conditions of everything you do must be choice, love, passion.” – Nadia Boulanger
  2. “More business is lost every year through neglect than through any other cause.” – Rose Kennedy

  3. “Give me a lever long enough and a fulcrum on which to place it, and I shall move the world.” – Archimedes

  4. “A person who won’t read has no advantage over one who can’t read.” – Mark Twain
  5. “The best way out is always through.” – Robert Frost

  6. “Start by doing what’s necessary; then do what’s possible; and suddenly you are doing the impossible.” – Francis of Assisi
  7. “Without labor nothing prospers.” – Sophocles

  8. “Intellectuals solve problems, geniuses prevent them.” – Albert Einstein
  9. “This is the precept by which I have lived: Prepare for the worst; expect the best; and take what comes.” – Hannah Arendt

  10. “The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller

  11. “He who is brave is free.” – Lucius Annaeus Seneca
  12. “When something is important enough, you do it even if the odds are not in your favor.” – Elon Musk

  13. “I choose a block of marble and chop off whatever I don’t need.” – Auguste Rodin

  14. “Hope is the only bee that makes honey without flowers.” – Robert Green Ingersoll

  15. “He who knows that enough is enough will always have enough.” – Lao Tzu

  16. “Plans to protect air and water, wilderness and wildlife are in fact plans to protect man.” – Stewart Udall
  17. “In order to carry a positive action we must develop here a positive vision.” – Dalai Lama

  18. “A hero is someone who understands the responsibility that comes with his freedom.” – Bob Dylan
  19. “Inflation destroys savings, impedes planning, and discourages investment. That means less productivity and a lower standard of living.” – Kevin Brady
  20. “If we give something positive to others, it will return to us. If we give negative, that negativity will be returned.” – Allu Arjun
  21. “A good plan violently executed now is better than a perfect plan executed next week.” ~ George S. Patton
  22. “You must do the things you think you cannot do.”- Eleanor Roosevelt
  23. “Success is dependent on effort.” – Sophocles
  24. “Nobody who ever gave his best regretted it.” – George Halas
  25. “Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
  26. “And when I breathed, my breath was lightning.” – Black Elk
  27. “Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
  28. “You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
  29. “If you want a guarantee, buy a toaster.” – Clint Eastwood
  30. “We are an impossibility in an impossible universe.” – Ray Bradbury
  31. “If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
  32. “I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
  33. Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
  34. “It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
  35. “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
  36. Surprise is the greatest gift which life can grant us.” –  Boris Pasternak
  37. “Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran 
  38. “Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
  39. “All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
  40. “There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” –  Colin Powell
  41. “There is more to life than increasing its speed.” – Mahatma Gandhi
  42. “Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
  43. “Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
  44. “Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
  45. “In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
  46. “Life is too short for long-term grudges.” – Elon Musk
  47. There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
  48. “Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
  49. “The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
  50. “Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
  51. “Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
  52. “But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
  53. “Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
  54. “Let there be work, bread, water and salt for all.” – Nelson Mandela
  55. “The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
  56. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
  57. “I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
  58. “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
  59. “If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
  60. “Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
  61. “Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
  62. “Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
  63. “You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
  64. “Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
  65. “Delete the negative; accentuate the positive!” – Donna Karan
  66. “It’s crazy how fast time flies and how things progress.” – Nathan Chen
  67. “The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
  68. “Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
  69. “Everything has beauty, but not everyone sees it.” – Confucius
  70. A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
  71. “Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
  72. “A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
  73. “The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
  74. “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
  75. “I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
  76. “Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
  77. “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
  78. “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
  79. “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
  80. “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
  81. “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
  82. “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
  83. “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
  84. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
  85. “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
  86. “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
  87. “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
  88. “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
  89. “There is little that can withstand a man who can conquer himself.” – Louis XIV
  90. “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
  91. “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
  92. “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
  93. “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese 
  94. “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
  95. “Never do anything against conscience even if the state demands it.”– Albert Einstein
  96. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
  97. “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
  98. “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
  99. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
  100. “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
  101. “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
  102. “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
  103. “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
  104. “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch 
  105. “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
  106. “The secret of getting ahead is getting started.” – Mark Twain
  107. “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe

Videos