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Thanksgiving Holiday-Shortened Week Ends With A Win – $DECK $INDP $LTRN $MODD $SHIP $SONO $STNE Rise!

By John F. Heerdink, Jr.
Quote of the Day: “One that would have the fruit must climb the tree.” – Thomas Fuller



Happy Saturday!

I hope all proceeded along a positive trend this week for you and yours.

As for the broad markets this week, stocks moved higher albeit on lower trading volume totals, but nevertheless less a win overall. A number of macroeconomic reports hit the presses again this week. On Monday, the October Leading Indicators report came in at -.8. On Tuesday, the October Existing Home Sales report came in lower at 3.79M. On Wednesday, the Initial jobless claims report for the week ending November 18 confirmed a 24k drop to 209k and the continuing jobless claims report for the week ending November 11 are in at 1.84M off 22k. The Durable goods orders report for October fell 5.4% M/M. The final reading for the University of Michigan Consumer Sentiment Index report for November clocked in at lower again at 61.3. The MBA Mortgage Applications Index report also moved up 3% wk/wk as refinance applications rose 2% & purchase applications rose 3%. On Friday, the preliminary November S&P Global US Manufacturing PMI report came in lower at 49.4 & the preliminary November S&P Global US Services PMI report clocked in slightly higher at 50.8.

Accordingly, the yield curve rose after last week’s significant pullback with the 2-yr yield moving up 5bps to 4.95% and the 10-yr moving up 3bps to 4.47%. The U.S. Dollar Index also fell again this week from 103.82 to 103.42. The CBOE Volatility Index (^VIX) also continued to pull back again by 7.08% closing at $12.46. On positive note oil prices continued to fall and closed down by .3% ending at $75.81/bbl and is back in to the traditionally acceptable range ($60-$80).

At the end of the week, the Dow 30 closed at 35,390.15 (+1.3%) this week and is now up 6.8% YTD.

The S&P 500 closed at 4,559.34 (+1%) for the week and is now up 18.7% YTD. 11 of the 11 sectors moved higher this week as the top 3 performing sectors were the health care sector up 2.2%, the consumer staples sector up 1.4%, and the communication services sector up 1.3%.

The Nasdaq closed at 14,250.85 (+.9%) and is now up 36.2% YTD.  

The Magnificent Seven closed as follows over the last 5-days: Alphabet (GOOG) closing at $138.22, -.35%, Amazon (AMZN) closing at $146.74, +2.74%, Apple (AAPL, $189.97, +.14%), Meta Platforms (META) closing at $338.23, +1.21%, Microsoft (MSFT) closing at $377.43, +.33%, NVIDIA (NVDA) closing at $477.76, -3.44% & Tesla (TSLA) closing at $235.45, +.80%.

The small caps on the Russell 2000 closed at 1,807.50 (+.5%) for the week & is now 2.6% YTD. The MicroCaps also moved significantly higher this week as the iShares Micro-Cap ETF (IWC) closed at $101.27, +2.81% this week, but is still down 6.09% YTD after establishing a new 52-wk low at $90.70 recently.

Bank stocks on the SPDR S&P Regional Banking ETF (KRE) dropped .29% over the last 5-days to close at $44.40 and is now down 24.41% YTD & the SPDR S&P Bank ETF (KBE) moved up .33% over the last 5-days to close at $39.50.

The Biotech sector rebounded this week.  The Nasdaq Biotechnology ETF (IBB) closed at $119.36, +1.99% over the last 5-days and is now down 9.09% YTD, the NYSE ARCA Biotech Index (^BTK) closed at 4,839.86, +1.91% over the last 5-days and is now down 8.36% YTD, & the SPDR S&P Biotech ETF (XBI) closed at $73.66, +5.03% over the last 5-days, & is now down 11.25% YTD. The 52-week range is is now $63.80-$92.60 after establishing a new 52-wk low this week.

Cathie Wood’s ARK Innovation ETF (ARKK) closed at $44.88, +6.33% over the last 5-days and is up 43.66% YTD.   

The iShares U.S. Healthcare ETF (IYH) closed at $274.02, +2.07% over the last 5-days and is now down 3.42% YTD.    

From the world of cryptocurrency, Bitcoin (BTC) moved to $37,758.86, +5.43% over the course of the last 5-days at the time of the completion of this message &  is up 128.54% over the last year.

Gold prices closed at $2,007 up from $1,985 over the last 5-days.  Silver prices closed at $24.18 up from $23.31 over the last 5-days. The Global X Silver ETF (SIL) closed at $26.17, +1.51% over the last 5-days.




VP Watchlist Updates


 
 
 
Modular Medical, Inc. (NASDAQ:MODD, $1.295, +23.33% over the last 5-days), is a development-stage medical device company that intends to launch the next generation of insulin delivery technology. Using its patented technologies, the company seeks to eliminate the tradeoff between complexity and efficacy, thereby making top quality insulin delivery both affordable and simple to learn. Their mission is to improve access to the highest standard of glycemic control for people with diabetes taking it beyond “superusers” and providing “diabetes care for the rest of us.” Modular Medical was founded by Paul DiPerna, a seasoned medical device professional and microfluidics engineer. Prior to founding Modular Medical, Mr. DiPerna was the founder (in 2005) of Tandem Diabetes and invented and designed its t:slim insulin pump. More information is available at https://modular-medical.com.

On Oct, 31, Modular Medical provided an update on its ongoing pre-submission testing and timeline for submission of its MODD-1 insulin pump (the “MODD-1”) to the U.S. Food and Drug Administration (“FDA”). The Company has made substantial progress on completing many of the tests required for submission and now has results back from some of the longest lead time tests, including insulin stability and potency. Modular Medical believes the test results received from multiple third-party laboratory tests are sufficient for submission of the MODD1 to the FDA for clearance, subject to the completion of other ongoing tests and reports. Jeb Besser, CEO of Modular Medical, commented, “The Modular Medical team has continued to make rapid progress towards our 510(k) submission to the FDA, since the completion of our pilot manufacturing line in August. While there is still additional testing to be done, we are starting to gain better visibility on our submission timeline, and we currently expect to make our FDA submission around year end 2023. We remain excited about our opportunity to bring access to better insulin delivery to underserved segments of the market.”

 
 

Lantern (LTRN) closed at $4.032, +4.73% over the last 5-days. Lantern is an Artificial Intelligence (AI) firm that is transforming the cost, pace, and timeline of oncology drug discovery and development and specifically is developing targeted and transformative cancer therapies using its proprietary RADR® AI and machine learning (“ML”) platform with multiple clinical stage drug programs.

Check out this Lou Basenese, Public Ventures President & Chief Market Strategist, interview with Varney & Company on FOX where he shares his views on several ‘under the radar’ AI companies, including AI firm Lantern Pharma. Here’s the link at Vimeo: https://vimeo.com/883266795/28d49860cf?share=copy

On Nov. 8, Lantern announced operational highlights and financial results for the third quarter ended September 30, 2023 highlighting the following: 

  • Received IND clearance from FDA to initiate Phase 1 clinical trial for LP-284, a first-in-human trial for advanced, refractory non-Hodgkin’s lymphomas (NHL). 
  • Dosed initial patient in Phase 1 with LP-184, a clinical trial for multiple advanced solid tumors that are refractory to standard-of-care therapies.
  • Progressed Phase 2 LP-300 Harmonic™ clinical trial towards enrollment in East Asian countries where 30-35+% of all lung cancer cases occur in never-smokers with NSCLC; continued expansion of additional clinical trial sites in the US and increased focus on recruitment activity with advocacy groups.
  • Developed initial proof-of-concept and preclinical evidence for a novel cryptophycin-based ADC (antibody-drug conjugate); initial data is planned to be shared in January 2024.
  • Furthered development of Lantern’s AI platform, RADR®, to include modules for the streamlined development of ADCs and the prediction of drug combinations with existing approved checkpoint inhibitors.
  • Approximately $45 million in cash, cash equivalents, and marketable securities as of September 30, 2023, is anticipated to provide a cash runway into at least Q3 of 2025.

As a quick follow up to Tribe Public’s recent CEO Presentation events that were held on the West Coast, our sister organization held a brief webinar-based Q&A session with Panna Sharma, CEO of Lantern, to have him address a few questions. The video has now ben published at the Tribe Public YouTube Channel the brief ~10-minute informative session can be viewed now by clicking here.

On Oct. 3, Lantern announced that in vivo data highlighting the enhanced efficacy of Lantern’s drug candidate LP-184 in glioblastoma (GBM) were published in Clinical Cancer Research, a journal of the American Association for Cancer Research. LP-184 is a unique small molecule with low nanomolar activity and favorable CNS penetration. LP-184 utilizes its powerful mechanism of action, known as synthetic lethality, to exploit common vulnerabilities in solid tumor and CNS cancers with DNA damage repair (DDR) deficiencies. In addition, Lantern’s AI platform, RADR®, has highlighted overlapping gene dependency profiles between GBM tumorigenesis and sensitivity to LP-184, such as EGFR activation pathways. The article, entitled “Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma” can be accessed here.

 

Panna Sharma is the President, CEO, and Board Member of Lantern Pharma Inc.

“The data highlighted in Clinical Cancer Research solidify LP-184 as a promising therapeutic for GBM, with LP-184 having inhibited the viability and growth of multiple GBM models including temozolomide-resistant and MGMT-expressing cells,” stated Panna Sharma, Lantern’s President and CEO.

“The rapid advancement of LP-184 into a first-in-human Phase 1 trial provides strong validation of the power of our AI-enabled approach to drug development. This approach is about more than just developing new treatments, it’s about making them more targeted, more effective, and ultimately doing all of this more efficiently. This publication demonstrates our ability to deliver on these aspirations and introduce new therapeutic programs in areas where there is significant unmet patient need.”


Deckers Brands (NYSE: DECK, $637.07, +3.51% over the last 5-days), a global leader in designing, marketing, and distributing innovative footwear, apparel, and accessories, announced financial results recently for the second fiscal quarter ended September 30, 2023. The Company also provided an update to its financial outlook for the full fiscal year ending March 31, 2024. “The strength of demand for our HOKA and UGG brands continued to drive exceptional performance, producing record revenue and earnings for Deckers in both the second quarter and first half of fiscal year 2024,” said Dave Powers, President and Chief Executive Officer. “Our team’s ability to deliver compelling products that create emotional connections with consumers through engaging marketing campaigns, differentiates our brands in a competitive marketplace. This, paired with our strategic approach to marketplace management, led by our DTC channel, remains paramount to the success of our brands and Company. We are focused on maintaining the integrity of our healthy brands to deliver the results detailed in our increased outlook, while remaining aligned with long-term objectives.”



Shares of Indaptus Therapeutics, Inc. (Nasdaq: INDP) closed at $2.10, +2.94% over the last 5-days. INDP stocks is also up 44.83% YTD.

Indaptus is a company with the ability to harness both the body’s innate and adaptive immune responses, believes that they are uniquely positioned to revolutionize the treatment of cancer and certain infectious diseases. Indaptus Therapeutics has evolved from more than a century of immunotherapy advances. The Company’s novel approach is based on the hypothesis that efficient activation of both innate and adaptive immune cells and pathways and associated anti-tumor and anti-viral immune responses will require a multi-targeted package of immune system-activating signals that can be administered safely intravenously (i.v.). Indaptus’ patented technology is composed of single strains of attenuated and killed, non-pathogenic, Gram-negative bacteria producing a multiple Toll-like receptor (TLR), Nucleotide oligomerization domain (Nod)-like receptor (NLR) and Stimulator of interferon genes (STING) agonist Decoy platform. The products are designed to have reduced i.v. toxicity, but largely uncompromised ability to prime or activate many of the cells and pathways of innate and adaptive immunity. Decoy products represent an antigen-agnostic technology that have produced single-agent activity against metastatic pancreatic and orthotopic colorectal carcinomas, single agent eradication of established antigen-expressing breast carcinoma, as well as combination-mediated eradication of established hepatocellular carcinomas and non-Hodgkin’s lymphomas in standard pre-clinical models, including syngeneic mouse tumors and human tumor xenografts.

In pre-clinical studies tumor eradication was observed with Decoy products in combination with anti-PD-1 checkpoint therapy, low-dose chemotherapy, a non-steroidal anti-inflammatory drug, or an approved, targeted antibody. Combination-based tumor eradication in pre-clinical models produced innate and adaptive immunological memory, involved activation of both innate and adaptive immune cells, and was associated with induction of innate and adaptive immune pathways in tumors after only one i.v. dose of Decoy product, with associated “cold” to “hot” tumor inflammation signature transition. IND-enabling, nonclinical toxicology studies demonstrated safe i.v. administration without sustained induction of hallmark biomarkers of cytokine release syndromes, possibly due to passive targeting to liver, spleen, and tumor, followed by rapid elimination of the product. Indaptus’ Decoy products have also produced significant single agent activity against chronic hepatitis B virus (HBV) and chronic human immunodeficiency virus (HIV) infections in pre-clinical models.

On Nov. 6, Indaptus announced interim data from the first cohort of four patients in the Phase 1 INDP-D101 trial of its lead compound, Decoy20. A broad expression of cytokines and chemokines associated with innate and adaptive anti-tumor immune responses was observed, while adverse events were generally tolerable and resolved within 30 minutes to three days. Decoy20 is designed to “re-set” the immune system’s response to cancer. The poster was presented on November 4, 2023, at the Society for Immunotherapy of Cancer in San Diego.

“We are impressed that we saw short-term induction of more than 50 cytokines, chemokines and biomarkers and believe this is unprecedented with a single agent. These early data support our long-standing hypothesis that the Decoy platform may induce robust immune responses across multiple types of immune cells that we believe are important for the eradication of solid tumors,” commented Indaptus CEO Jeffrey Meckler. Learn more here. 

Also, on Nov. 6, Indaptus announced financial results for the third quarter ended September 30, 2023 and provided a corporate update.

We continue to be encouraged by early results from our first cohort of patients in the INDP-D101 trial evaluating Decoy20 for the treatment of solid tumors. As we recently reported and presented at the Society for Immunology in Cancer (SITC) conference, all four first cohort patients have maintained stable disease since receiving their single dose and presented evidence of immune activation, along with short-lived adverse events consistent with Decoy20’s mechanism of action, and we look forward to continuing to track them. In the meantime, we have already dosed our first patient in the second cohort, for which we have titrated the dose down in anticipation of a similar response. We continue to expect to have the second cohort completed by early 2024, which would provide guidance for the selection for the recommended Phase 2 dose for subsequent multi-dosing and combination studies, which are also planned for 2024,” said Jeffrey Meckler, Chief Executive Officer of Indaptus. “We are also fortunate to be receiving the benefit of our appointment of industry veteran, Roger Waltzman, M.D., as our Chief Medical Officer, who has already proven valuable even in this short period. We anticipate continuing to benefit from his expertise as we move forward with our Phase 1 trial and further develop the Decoy platform. In the meantime, we are prudently managing our cash position.”

On Sept, 29, Tribe Public hosted a Webinar Presentation and Q&A Event titled “Immunotherapy Reimagined” Indaptus Therapeutics’ (NASDAQ: INDP) CEO, Jeffrey Meckler delivered a presentation & also addressed a 5-10 minute Q&A session at the end of the presentation. You may view it now by clicking here. 


Learn more about Indaptus Therapeutics (NASDAQ: INDP) at the VP Watchlist page by clicking here.
 

 

 

Shares of ADT Inc. (ADT), the most trusted brand in smart home and small business security, closed at $5.99, +.84% over the last 5-days. ADT released its third quarter 2023 financial results recently and beat expectations. They highlighted the following progress: Significant balance sheet improvement driven by divestiture of commercial business, Record high CSB recurring monthly revenue balance driven by strong retention, Improved capital efficiency with record revenue payback of 2.0 years, & Continued innovation in core smart home security markets and rationalization of solar footprint.

On Oct. 2, GTCR, a leading private equity firm, announced that it has closed the acquisition of ADT’s commercial security, fire and life safety security businessfrom ADT Inc. (“ADT”, NYSE: ADT). Moving forward as a standalone organization, ADT Commercial will rebrand as Everon. GTCR will partner with former Protection1 executives Dan Bresingham and Tim Whall, along with other members of ADTC leadership, to acquire the Company, one of the leading national providers of electronic security and fire safety services to commercial enterprises and multi-site national accounts. Mr. Bresingham, former leader of ADT’s commercial security, fire and life safety business, will become Chief Executive Officer of Everon and Mr. Whall will serve as an active director on the Company’s Board.


Shares of Seanergy Maritime Holdings Corp. (SHIP), the only pure-play Capesize ship-owner publicly listed in the U.S. closed at $6.58, +9.85% over the last 5 days. Seanergy (NASDAQ: SHIP) announced that it will release its financial results for the third quarter and nine months ended September 30, 2023, prior to the open of the market in New York on Tuesday, November 14, 2023.


Brad Hansen CEO of Holu Hou Energy (HHE), a company that uniquely brings state-of-the-art renewable energy and energy storage systems to the Single-Family Residential, Multi-Dwelling Unit Residential, and Commercial building markets, presented at our sister organization’s Tribe Public Webinar Presentation and Q&A Event titled “Discover How Multi-Dwelling Units Are Profitably Implementing Solar Energy Today.” The event video has now been published at the Tribe Public YouTube Channel and can be view now by clicking on this link

Note that HHE was recognized as the 2023 winner of the Innovative Tech Company of the Year at the 13th annual Pacific Edge Business Achievement Awards Gala in Honolulu, Hawai’i. With operations in California, Hawai’i, Wisconsin, and Shanghai, HHE engineers proprietary storage system and control platform solutions, including a breakthrough HHE “EnergyCluster” technology that is key to the development of the Multi-Dwelling Unit Residential housing market that uniquely allows for sharing amongst local units of excess energy created by solar energy production. This technology uniquely solves the key problems for installing solar energy for MDU tenant units: tenant load variability and tenant churn. Thus, HHE is essentially good for all parties. It is a vital partner for investors and asset owners who are seeking MDU renewable energy solutions that create a new and significant multi-year revenue stream. For tenants, the adoption is non-disruptive and, in practice, allows for energy control and localized resiliency. 

On Nov. 2, Holu Hou Energy LLC announced that it is has closed a $20M construction financing facility in support of the construction of Hawaii’s largest solar and energy storage project pipeline. The funding will enable procurement of the materials and EPC resources to construct MDU projects slated for completion in the next 4-quarters. HHE’s EnergyCluster Technology has  reportedly enabled the Largest Non-Utility Solar Project Pipeline in Hawaii – Approaching $1.0 Billion in Value.

 
 
StoneCo Ltd. (Nasdaq: STNE, $14.50, ++5.99% over the last 5-days) on Nov. 10, reported its financial results for its third quarter ended September 30, 2023. They highlighted a strong quarter with Adjusted EBT reaching R$545 million, up 228% year over year, on accelerating MSMB TPV growth of 19.9%, resulting in Adjusted Net income of R$435 million, up 302% year over year.
 
 


Thanks again for your attention this week. Please continue to share your thoughts, questions, & ideas as we move forward. 

In the meantime, please enjoy the balance of the weekly newsletter’s videos, quotes, updates and let’s find ways to crush it again as we move forward!

Investing & Inspiration

  1. “One that would have the fruit must climb the tree.” – Thomas Fuller
  2. “Someone is sitting in the shade today because someone planted a tree a long time ago.” – Warren Buffett
  3. “We relish news of our heroes, forgetting that we are extraordinary to somebody too.” – Helen Hayes
  4. “A life spent making mistakes is not only more honorable, but more useful than a life spent doing nothing.” – George Bernard Shaw
  5. “Everything in the world may be endured except continual prosperity.”  – Johann Wolfgang von Goethe
  6. “Nine-tenths of wisdom is being wise in time.” – Theodore Roosevelt
  7. “Time is money.” – Benjamin Franklin
  8. “Change before you have to.” – Jack Welch
  9. “Our deeds determine us, as much as we determine our deeds.” – George Eliot
  10. “The Universe is under no obligation to make sense to you.” – Neil deGrasse Tyson
  11. “Care and diligence bring luck.” – Thomas Fuller
  12. “Nobody made a greater mistake than he who did nothing because he could do only a little.” – Edmund Burke
  13. “A man who is a master of patience is master of everything else.” – George Savile
  14. “Once you replace negative thoughts with positive ones, you’ll start having positive results.” – Willie Nelson
  15. “Endurance is nobler than strength, and patience than beauty.” – John Ruskin
  16. “Act as if what you do makes a difference. It does.” – William James
  17. “Let us be grateful to people who make us happy, they are the charming gardeners who make our souls blossom.” –  Marcel Proust
  18. “Strength and growth come only through continuous effort and struggle.” – Napoleon Hill
  19. “Science may never come up with a better office communication system than the coffee break.” – Earl Wilson
  20. “If everyone is moving forward together, then success takes care of itself.” – Henry Ford
  21. “Hope is like the sun, which, as we journey toward it, casts the shadow of our burden behind us.”– Samuel Smiles
  22. “Patriotism is supporting your country all the time, and your government when it deserves it.” – Mark Twain
  23. “What would life be if we had no courage to attempt anything?” – Vincent Van Gogh
  24. “The biggest risk is not taking any risk… In a world that is changing really quickly, the only strategy that is guaranteed to fail is not taking risks.” – Mark Zuckerberg
  25. “Our lives improve only when we take chances – and the first and most difficult risk we can take is to be honest with ourselves.” – Walter Anderson
  26. “Action is the foundational key to all success.” – Pablo Picasso
  27. “Success is never final, failure is never fatal. It’s courage that counts.” – John Wooden
  28. “Innovation distinguishes between a leader and a follower.” – Steve Jobs
  29. “All the art of living lies in a fine mingling of letting go and holding on.” – Havelock Ellis
  30. “The size of your success is measured by the strength of your desire; the size of your dream; and how you handle disappointment along the way.” – Robert Kiyosaki
  31. “O, wind, if winter comes, can spring be far behind?” – Percy Bysshe Shelley
  32. “Patience is a virtue, and I’m learning patience. It’s a tough lesson.” – Elon Musk
  33. “Be true to your work, your word, and your friend.” – John Boyle O’Reilly
  34. “Believe in yourself! Have faith in your abilities! Without a humble but reasonable confidence in your own powers you cannot be successful or happy.” – Norman Vincent Peale
  35. “Surprise is the greatest gift which life can grant us.” – Boris Pasternak
  36. “Logic will get you from A to B. Imagination will take you everywhere.” – Albert Einstein
  37. “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
  38. “Do exactly what you would do if you felt most secure.” – Meister Eckhart
  39. “Life lived for tomorrow will always be just a day away from being realized.” – Leo Buscaglia
  40. “Wisdom is oftentimes nearer when we stoop than when we soar.” – Wordsworth
  41. “Take chances, make mistakes. That’s how you grow. Pain nourishes your courage. You have to fail in order to practice being brave.” – Mary Tyler Moore
  42. “A single twig breaks, but the bundle of twigs is strong.” – Tecumseh
  43. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
  44. “There is little that can withstand a man who can conquer himself.” – Louis XIV
  45. “The limits of the possible can only be defined by going beyond them into the impossible.” – Arthur C. Clarke
  46. “Be faithful in small things because it is in them that your strength lies.” – Mother Teresa
  47. “The future rewards those who press on. I don’t have time to feel sorry for myself. I don’t have time to complain. I’m going to press on.” – Barack Obama
  48. “By three methods we may learn wisdom: First, by reflection, which is noblest; Second, by imitation, which is easiest; and third by experience, which is the bitterest.” – Confucius
  49. “No man was ever wise by chance.” – Lucius Annaeus Seneca
  50. “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
  51. “It is not in the stars to hold our destiny but in ourselves.” – William Shakespeare
  52. “It does not matter how slowly you go as long as you do not stop.” – Confucius

  53. “I want to put a ding in the universe.” – Steve Jobs

  54. “Research is creating new knowledge.” – Neil Armstrong

  55. “The reward for work well done is the opportunity to do more.” – Jonas Salk
  56. “Man is a creative retrospection of nature upon itself.” – Karl Wilhelm Friedrich Schlegel
  57. “There’s something about taking a plow and breaking new ground. It gives you energy.” – Ken Kesey
  58. “Success seems to be largely a matter of hanging on after others have let go.” – William Feather

  59. “The essential conditions of everything you do must be choice, love, passion.” – Nadia Boulanger
  60. “More business is lost every year through neglect than through any other cause.” – Rose Kennedy

  61. “Give me a lever long enough and a fulcrum on which to place it, and I shall move the world.” – Archimedes

  62. “A person who won’t read has no advantage over one who can’t read.” – Mark Twain
  63. “The best way out is always through.” – Robert Frost

  64. “Start by doing what’s necessary; then do what’s possible; and suddenly you are doing the impossible.” – Francis of Assisi
  65. “Without labor nothing prospers.” – Sophocles

  66. “Intellectuals solve problems, geniuses prevent them.” – Albert Einstein
  67. “This is the precept by which I have lived: Prepare for the worst; expect the best; and take what comes.” – Hannah Arendt

  68. “The best and most beautiful things in the world cannot be seen or even touched – they must be felt with the heart.” – Helen Keller

  69. “He who is brave is free.” – Lucius Annaeus Seneca
  70. “When something is important enough, you do it even if the odds are not in your favor.” – Elon Musk

  71. “I choose a block of marble and chop off whatever I don’t need.” – Auguste Rodin

  72. “Hope is the only bee that makes honey without flowers.” – Robert Green Ingersoll

  73. “He who knows that enough is enough will always have enough.” – Lao Tzu

  74. “Plans to protect air and water, wilderness and wildlife are in fact plans to protect man.” – Stewart Udall
  75. “In order to carry a positive action we must develop here a positive vision.” – Dalai Lama

  76. “A hero is someone who understands the responsibility that comes with his freedom.” – Bob Dylan
  77. “Inflation destroys savings, impedes planning, and discourages investment. That means less productivity and a lower standard of living.” – Kevin Brady
  78. “If we give something positive to others, it will return to us. If we give negative, that negativity will be returned.” – Allu Arjun
  79. “A good plan violently executed now is better than a perfect plan executed next week.” ~ George S. Patton
  80. “You must do the things you think you cannot do.”- Eleanor Roosevelt
  81. “Success is dependent on effort.” – Sophocles
  82. “Nobody who ever gave his best regretted it.” – George Halas
  83. “Lots of people want to ride with you in the limo, but what you want is someone who will take the bus with you when the limo breaks down.” ~ Oprah Winfrey
  84. “And when I breathed, my breath was lightning.” – Black Elk
  85. “Moderation is the silken string running through the pearl chain of all virtues.” – Joseph Hall
  86. “You are the sum total of everything you’ve ever seen, heard, eaten, smelled, been told, forgot – it’s all there. Everything influences each of us, and because of that I try to make sure that my experiences are positive.” – Maya Angelou
  87. “If you want a guarantee, buy a toaster.” – Clint Eastwood
  88. “We are an impossibility in an impossible universe.” – Ray Bradbury
  89. “If you think in terms of a year, plant a seed; if in terms of ten years, plant trees; if in terms of 100 years, teach the people.” – Confucius
  90. “I’d rather attempt to do something great and fail than to attempt to do nothing and succeed.” – Robert H. Schuller
  91. Do your little bit of good where you are; it’s those little bits of good put together that overwhelm the world.” Desmond Tutu
  92. “It takes considerable knowledge just to realize the extent of your own ignorance.” – Thomas Sowell
  93. “Do not dwell in the past, do not dream of the future, concentrate the mind on the present moment.” – Buddha”
  94. Surprise is the greatest gift which life can grant us.” –  Boris Pasternak
  95. “Trust in dreams, for in them is hidden the gate to eternity.” – Khalil Gibran 
  96. “Always be yourself, express yourself, have faith in yourself, do not go out and look for a successful personality and duplicate it.” – Bruce Lee
  97. “All life is an experiment. The more experiments you make the better.” – Ralph Waldo Emerson
  98. “There are no secrets to success. It is the result of preparation, hard work, and learning from failure.” –  Colin Powell
  99. “There is more to life than increasing its speed.” – Mahatma Gandhi
  100. “Your attitude is like a box of crayons that color your world. Constantly color your picture gray, and your picture will always be bleak. Try adding some bright colors to the picture by including humor, and your picture begins to lighten up.” – Allen Klein
  101. “Definiteness of purpose is the starting point of all achievement.” – W. Clement Stone
  102. “Success usually comes to those who are too busy to be looking for it.” – Henry David Thoreau
  103. “In matters of truth and justice, there is no difference between large and small problems, for issues concerning the treatment of people are all the same.” – Albert Einstein
  104. “Life is too short for long-term grudges.” – Elon Musk
  105. There cannot be a crisis next week. My schedule is already full.” – Henry Kissinger
  106. “Success consists of getting up just one more time than you fall.” – Oliver Goldsmith
  107. “The Earth is the cradle of humanity, but mankind cannot stay in the cradle forever.” – Konstantin Tsiolkovsky
  108. “Ours is a world of nuclear giants and ethical infants. We know more about war that we know about peace, more about killing that we know about living.” – Omar N. Bradley
  109. “Beauty surrounds us, but usually we need to be walking in a garden to know it.” – Rumi
  110. “But man is not made for defeat. A man can be destroyed but not defeated.” – Ernest Hemingway
  111. “Don’t watch the clock; do what it does. Keep going.” – Sam Levenson
  112. “Let there be work, bread, water and salt for all.” – Nelson Mandela
  113. “The social object of skilled investment should be to defeat the dark forces of time and ignorance which envelope our future.” – John Maynard Keynes
  114. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
  115. “I know not with what weapons World War III will be fought, but World War IV will be fought with sticks and stones.” – Albert Einstein
  116. “It is the fight alone that pleases us, not the victory.” – Blaise Pascal
  117. “If you can’t describe what you are doing as a process, you don’t know what you’re doing.” – W. Edwards Deming
  118. “Never interrupt your enemy when he is making a mistake.” – Napoleon Bonaparte
  119. “Be sure you put your feet in the right place, then stand firm.” – Abraham Lincoln
  120. “Without investment there will not be growth, and without growth there will not be employment.” – Muhtar Kent
  121. “You have to do your own growing no matter how tall your grandfather was.” – Abraham Lincoln
  122. “Victory has a thousand fathers, but defeat is an orphan.” – John F. Kennedy
  123. “Delete the negative; accentuate the positive!” – Donna Karan
  124. “It’s crazy how fast time flies and how things progress.” – Nathan Chen
  125. “The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.” – Albert Einstein
  126. “Life isn’t about finding yourself. Life is about creating yourself.” – George Bernard Shaw
  127. “Everything has beauty, but not everyone sees it.” – Confucius
  128. A man must be big enough to admit his mistakes, smart enough to profit from them, and strong enough to correct them.” – John C. Maxwell
  129. “Walking with a friend in the dark is better than walking alone in the light.” – Helen Keller
  130. “A man who dares to waste one hour of time has not discovered the value of life.” – Charles Darwin
  131. “The greater danger for most of us lies not in setting our aim too high and falling short; but in setting our aim too low, and achieving our mark.” – Michelangelo
  132. “Progress is man’s ability to complicate simplicity.” – Thor Heyerdahl
  133. “I like to encourage people to realize that any action is a good action if it’s proactive and there is positive intent behind it.” – Michael J. Fox
  134. “Nothing is impossible, the word itself says ‘I’m possible’!” – Audrey Hepburn
  135. “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
  136. “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
  137. “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
  138. “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
  139. “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
  140. “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
  141. “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
  142. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
  143. “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
  144. “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
  145. “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
  146. “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
  147. “There is little that can withstand a man who can conquer himself.” – Louis XIV
  148. “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
  149. “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
  150. “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
  151. “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese 
  152. “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
  153. “Never do anything against conscience even if the state demands it.”– Albert Einstein
  154. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
  155. “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
  156. “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
  157. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
  158. “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
  159. “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
  160. “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
  161. “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
  162. “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch 
  163. “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
  164. “The secret of getting ahead is getting started.” – Mark Twain
  165. “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe

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