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Tuesday’s Volatile Market Session Wrapped In FOMC Induced Anxiety – $FATE $INMB $INVO $NBSE $XLE Rise!

By John F. Heerdink, Jr.
Quote of The Day- “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye, Born: November 27, 1955

 
Tuesday’s market session took us on yet another volatile ride as investors continued to be anxious leading up to tomorrow’s conclusion of the FOMC meeting. We dipped significantly in the early going seeing the markets hit a session low approximately 30-minutes into the session while moving down 2.8%, then it staged a come back that still fell short as all indices closed in the red. The large cap indices ended with the S&P 500 closing at 4,356.45 (-1.22%), the Dow 30 closed at 34,297.73 (-.19%), & the Nasdaq closed at 13,539.29 (-2.28%). The relative strength of the Dow was powered by earnings beats via 4 components that moved higher including American Express (AXP, $172.96, +8.8%), IBM (IBM, $136.10, +5.7%), Johnson & Johnson (JNJ, $67.63, +2.9%), & 3M (MMM, $173.73, +.5%). 9 of the 11 sectors fueled the overall market decline, while the true pressure was headed by the growth side of the markets with the information technology sector falling 2.3%, the communication services sector falling 2.2%, & the consumer discretionary dropping 1.8%. However, if you were in the energy sector, then you were happy, as it jumped 4% as oil prices shot up another 2.5% to close at $84.37 & the XLE closed at $65.31, +3.88%. The Financials sector also moved up .5% as yield curve rose with the 10-yr Treasury moving up 5 basis points to 1.78% & the 2-yr yield moved up equal amount to 1.02%. The small caps on the Russell 2000 did not fair any better than the large caps as it closed at 2,004.03 (-1.45%), while the Microcaps also slipped with the iShares Micro-Cap ETF (IWC) closing at $124.94,-.64%. The much maligned biotech sector generally followed the overall markets path again today as the SPDR S&P Biotech ETF (XBI), a barometer of the smaller biotech stocks dipped to $88.89 prior to rebounding and actually turning green late in the day, but closed in the red too at $91.28, -.79%. The 52-wk range is $85.31 – $174.79.  Again, I hope that we have seen the low for the year in this sector!
 
The U.S. Dollar Index moved up .1% to close at 95.98, Bitcoin (BTC) closed at $36,663.87, +.60% over the last 24-hours, gold prices closed at $1,849/oz., +$5/oz. & silver closed at $23.86, -$.14. Two mining producers also pulled back again today as Hecla Mining Company (HL) fell to $5.20, +.58% and First Majestic Silver Corp. (AG) closed at $10.51, +.77%.
 
The macroeconomic schedule also delivered the Conference Board’s Consumer Confidence Index report which confirmed a decline to 113.8. The November FHFA Housing Price Index report confirmed a 1.1% M/M rise, while the November S&P Case-Shiller Home Price Index report also confirmed an 18.3% Y/Y rise.
 
FURTHER AFIELD
 
After the close today, Microsoft Corp. (MSFTm $288.49, -2.6%) announced the following results for the quarter ended December 31, 2021 beating Wall Street’s estimates:
 

· Revenue was $51.7 billion and increased 20%

· Operating income was $22.2 billion and increased 24%

· Net income was $18.8 billion and increased 21%

· Diluted earnings per share was $2.48 and increased 22%

Satya Nadella, chairman and chief executive officer of Microsoft stated, “Digital technology is the most malleable resource at the world’s disposal to overcome constraints and reimagine everyday work and life. As tech as a percentage of global GDP continues to increase, we are innovating and investing across diverse and growing markets, with a common underlying technology stack and an operating model that reinforces a common strategy, culture, and sense of purpose.”

Amy Hood, executive vice president and chief financial officer of Microsoft stated, “Solid commercial execution, represented by strong bookings growth driven by long-term Azure commitments, increased Microsoft Cloud revenue to $22.1 billion, up 32% year over year.”

 
VIEW NOW
 
 
On Jan. 11, I hosted a Tribe Public Webinar Presentation and Q&A Event with Nauticus Robotics (NASDAQ: CLAQ) Founder, Chairman & Chief Executive Officer, Nicolaus Radford & Eli Spiro, CEO of CleanTech Acquisition Corp for their presentation titled From Space to sea – Tesla of the Subsurface”. They were also available for a 5-10 minute Q&A session at the end of the presentation. You may view the event video at the Tribe Public YouTube Channel by clicking here. The event speaks, in part, to the overall oceanic economy, which counting both the seas and the shores, amounts to $2.5 trillion per year. Did you know that if the ocean were a country, it would have the seventh-largest GDP on Earth? That number could continue to grow — but only if our planet’s many seas remain in good health. We also learned about Nauticus Robotics and how they have developed revolutionary cloud-based autonomy software to enable a smarter and more sustainable ocean industry using its fleet of autonomous robots from the surface to the seabed. These robots are enabled by the Nauticus Software Suite, a platform of AI/ML technologies designed to disrupt the legacy methods in the marine industry. Its first product offering, Aquanaut, is the world’s first tetherless underwater robot capable of robust decision making for both long distance ocean data collection and close-in dexterous manipulation of the subsea environment, supporting government & defense and other commercial industry sectors. Nauticus’ software, robots, and services provide customers the necessary data collection, analytics, and subsea manipulation capabilities to support and maintain assets, while significantly reducing their operational and carbon footprints to improve offshore health, safety, and environmental exposure.
 
 
 
VP WATCHLIST UPDATES 
tesla
 
Apple (AAPL) closed at $159.78, -1.14%. According Bloomberg, Apple Inc. and Google warned U.S. lawmakers on Tuesday that bipartisan antitrust legislation aimed at curbing the power of big technology companies would harm the privacy and security of users if it becomes law.
 
Tesla (TSLA) closed at $918.40, -1.25%.  Tesla will post its financial results for the fourth quarter and full year ended December 31, 2021 after market close, tomorrow,  Wednesday, January 26, 2022. At that time, Tesla will issue a brief advisory containing a link to the Q4 and full year 2021 update, which will be available on Tesla’s Investor Relations website. Tesla management will hold a live question and answer webcast that day at 4:30 p.m. Central Time (5:30 p.m. Eastern Time) to discuss the Company’s financial and business results and outlook .Recently, Barrons reported that “Tesla delivered almost 71,000 vehicles from its Shanghai plant in December, according to Citigroup analyst Jeff Chung.” 
 
The Walt Disney Company (DIS) closed at $136.51, -.69%. Last week, to support the ongoing expansion of The Walt Disney Company’s direct-to-consumer business around the world and fuel the expanding pipeline of local and regional content for its streaming services, the Company announced that it is creating a new hub for international content creation under the direction of Rebecca Campbell as Chairman, International Content and Operations. In addition, the Company is making several key executive appointments to its Disney Media & Entertainment Distribution (DMED) segment under the leadership of its Chairman, Kareem Daniel. Disney will hold its annual meeting of shareholders on Wednesday, March 9, 2022 at 1:00 p.m. ET / 10:00 a.m. PT by virtual meeting and will be made available via webcast at www.disney.com/investors. Disney’s CEO Bob Chapek’s comp for the company’s fiscal 2021 grew to ~$32.5. easily doubling his take home last year.
 
 
On the small side, Atossa Therapeutics (NASDAQ: ATOS), a clinical-stage biopharmaceutical company seeking to develop innovative proprietary medicines in oncology and infectious disease with a current focus on breast cancer and COVID-19, rose to an intraday high of $1.337, prior to closing at $1.30, -.76% on 3.07M shares of trading volume.  On Jan. 18, Atossa announced it is advancing to enroll participants in Part B of its Phase 1/2a clinical study of AT-H201 in Australia, consisting of multiple ascending dose cohorts in healthy participants. The nebulized formulation, AT-H201, is being developed as an inhalation therapy for moderately to severely-ill hospitalized COVID-19 patients and for “long-haul” patients with post-infection pulmonary disease. Part A of the study, which consisted of a single ascending dose group of 4 cohorts of healthy participants, has now been completed. The Australian Human Research Ethics Committee has reviewed the safety data from Part A and has approved the study to proceed to Part B. “The results of the first part of the study were extremely encouraging and the ethics committee concluded we may now proceed to enroll the next group of participants,” said Steven Quay, M.D., Ph.D., Atossa’s CEO and President. “A record number of hospitalizations driven by the Omicron variant is producing a crisis at many healthcare facilities. Additional therapies to combat COVID-19 are desperately needed.” The Phase 1/2a placebo-controlled study will enroll a total of 60 healthy participants and moderately-ill hospitalized COVID-19 patients. The study has 4 parts: Part A – a single ascending dose part, Part B – a multiple ascending dose part, Part C – a combination part in healthy individuals, and Part D a combination in COVID-19 infected patients. The study is being conducted by Avance Clinical Pty Ltd., a leading Australian clinical research organization. AT-H201 is a proprietary combination of two drugs previously approved by the FDA to treat other diseases and by other administration routes. AT-H201 is intended to be inhaled via a nebulizer to improve compromised lung function for moderate to severely ill, hospitalized COVID-19 patients and for “long-haul” patients with post-infection pulmonary disease. In May 2020, we completed in vitro testing of AT-H201 which showed that the components of AT-H201 inhibit SARS-CoV-2 infectivity of VERO cells, which is a standard cell type being used to study infectivity of the coronavirus.
The Phase 1/2a study in Australia and other clinical studies must be successfully completed and regulatory approvals must be obtained before AT-H201 may be commercialized. No assurance can be given than studies will be successful or that regulatory approvals will be obtained.
 
On Jan. 10, Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to the development of programmed cellular immunotherapies for patients with cancer, announced that the U.S. Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for FT536, an off-the-shelf, multiplexed-engineered, iPSC-derived, chimeric antigen receptor (CAR) NK cell product candidate. FT536 is derived from a clonal master induced pluripotent stem cell (iPSC) line engineered with four functional elements, including a novel CAR that uniquely targets the α3 domain of the major histocompatibility complex (MHC) class I related proteins A (MICA) and B (MICB). MICA and MICB are stress proteins that are expressed at high levels on many solid tumors. The Company plans to initiate clinical investigation of FT536 as a monotherapy and in combination with tumor-targeting monoclonal antibody therapy for the treatment of multiple solid tumor indications. Shares of FATE closed at $39.87, +.89%. 
 
 
InMed Pharmaceuticals Inc. (NASDAQ: INM), a leader in the development, manufacturing and commercialization of rare cannabinoids, closed at $1.14, -3.39% after hitting an intraday high of $1.18. On Jan. 19, InMed announced that it has launched B2B sales of the rare cannabinoid cannabicitran (CBT) into the health and wellness sector. CBT is the first of several new product launches planned for the first half of 2022. InMed’s subsidiary, BayMedica, has received initial purchase orders and has commenced commercial sales of the ultra-rare cannabinoid CBT. CBT is the second rare cannabinoid to be launched by BayMedica, which also sells CBC wholesale as a raw ingredient to the health and wellness sector. Additionally, commercial scale production of cannabidivarin (CBDV) is underway, with tetrahydrocannabivarin (THCV) production scheduled to follow shortly thereafter. The Company expects to produce over 100kg of CBDV and THCV in the coming months to meet anticipated initial demand. Shane Johnson, SVP and General Manager of BayMedica stated, “We are delivering on our objective to launch additional rare cannabinoids in early 2022 in response to inbound demand. By midyear, we expect to have at least four rare cannabinoids available for the health and wellness markets, positioning us as a leading large scale supplier of high quality rare cannabinoids in these sectors. The launch of CBT further demonstrates our ability to produce rare cannabinoids at commercial scale, an achievement that very few companies have been able to accomplish. We are pleased with initial demand and we expect to grow sales over the coming quarters as we continue to expand our product portfolio of rare cannabinoids.” This emerging market is expected to grow significantly due to the increasing awareness of the potential benefits of cannabinoid-based products. According to the December 2021 Grand View Research report, the retail market for rare cannabinoids is expected to reach US$26 billion by 2028 with a forecasted compounded annual growth rate (CAGR) of >20% during the same period. With the availability of these rare cannabinoids at commercial scale, product manufacturers and consumer brands now have the ability to deliver differentiated products, including augmenting existing CBD-based products, to consumers in the health and wellness marketplace.
 
 
 
 
On Jan. 6, InMed’s CEO Eric A. Adams, Shane Johnson, SVP and General Manager of BayMedica and Chris Meiering, VP of Commercial Operations, presented at Tribe Public’s Webinar Presentation and Q&A Event titled “Addressing The Increasing Demand For Rare Cannabinoids.” On Jan. 5th, InMed issued its Annual Letter to Shareholders from President and CEO Eric A. Adams which stated, “Building on a very strong 2021, we are looking forward to 2022 with the continued advancement of our pharmaceutical drug development programs and, with our acquisition of BayMedica, transitioning to becoming a leading B2B supplier of rare cannabinoids to the consumer health and wellness sector. I’m very excited to provide updates on our progress as we begin to commercialize new products and explore an array of rare cannabinoids for their potential therapeutic applications.” Click here to read the letter
 
 
INmune Bio
 
Today, INmune Bio, Inc. (NASDAQ: INMB), a clinical-stage immunology company focused on developing treatments that harness the patient’s innate immune system to fight disease, announced that the company has entered into a pre-clinical research collaboration with Chinese University of Hong Kong (CUHK) to evaluate INKmune™ — the company’s pseudokine NK cell priming platform — in nasopharyngeal cancer (NPC), a type of head and neck cancer. The Strategic Partnership Award for Research Collaboration, which was granted by the CUHK Office of Academic Links, is between Prof. Michael Tong at CUHK and Prof. Mark Lowdell at University College London (UCL) and Chief Scientific Officer of INMB. The project provides INMB scientists working at UCL with access to the only three proven NPC cancer cell lines to test the ability of INKmune-primed NK cells to kill NPC tumors.
 
Prof. Lowdell stated, “Our colleagues at CUHK have been studying NK cell responses to NPC for many years but have not yet translated them into clinical trials. They have shown the need for cytokine activation with IL2 or IL15 to achieve tumor killing. We believe pseudokine activation by INKmune will provide all the relevant NK activating signals of IL2 and IL15 plus a host of other critical NK survival signals and generate memory-like NK cells. We are confident that these INKmune primed cells will kill NPC tumor cells very effectively and we look forward to a mutually beneficial collaboration.”
 
RJ Tesi, INmune Bio’s Chief Executive Officer stated, “Over 180,000 cases of NPC were diagnosed last year with 85% originating in Asia. Current treatments are quite poor, leading to high mortality rates. History of EBV infection (commonly known as mono) and genetic polymorphisms drive the incidence of the disease. This peer-reviewed grant and international collaboration targeting what has historically been a difficult to treat solid tumor validates the versatility of INKmune. We look forward to translating this work to the clinic in the near future.”
 
Shares of INVO Bioscience, Inc. (NASDAQ: INVO), a medical device company focused on commercializing the world’s only in vivo culture system (IVC), INVOcell®, climbed again today and closed at $3.09, +1.31% & legged up to $3.3, +6.8% in the aftermarkets, but still well off of its 52-wk high of $12.30. Last week, Maxim Group’s sell side analyst Jason McCarthy, Ph.D. initiated coverage with a Buy Rating Report titled “INVO Bioscience: Transforming Assisted Reproductive Technology with Intravaginal Culture” with a $7 Price Target.
 
On Dec. 16, INVO Bioscience, Inc. announced that it has entered into an expanded agreement with Ovoclinic, a group of clinics specialized in assisted reproductive treatments with four locations across Spain (Madrid, Marbella, Málaga, Ceuta) and collaborating centers around Europe, to accelerate adoption of INVOcell within their markets. The agreement includes the expanded adoption of INVOcell within Ovoclinic locations as well as establishing an INVO Center of Excellence for future training for the European Market. Cristina Gonzalez, embryologist and Quality Manager of Ovoclinic laboratories stated, “After several successful trials implementing the exciting INVOcell fertility treatment, Ovoclinic aims to provide its patients with this effective alternative to the processes used so far in Spain in the field of reproductive medicine. We consider INVOcell to be an effective method of natural reproduction that involves the future mother at the very first moment of the process. We are confident that this innovative treatment will help many patients to choose this new alternative solution to achieve their dream of forming a family by actively participating in the reproductive process.” According to the World Bank, Spain, with total population of approximately 47 million people, has one of the lowest fertility rates in Europe, affecting approximately 15% of the population, or one in seven couples of reproductive ages. According to reports, in 2010, there were approximately one million couples requesting assisted reproductive treatment, however only 22% received one or more assisted reproductive treatment cycles. The average waiting time for an IUI or IVF cycle in a public health facility was 339 days. Ovoclinic reports that they maintain the best technical and human resources to deal with all kinds of infertility problems along with the simplest and most natural treatments to the most complex and advanced techniques pioneered in Spain. Ovoclinic also works in partnership with Ovobank, the first European Donor Egg Bank in Europe.
 
Shares of NeuBase Therapeutics (NASDAQ: NBSE),  a biotechnology platform company Drugging the Genome™ to address disease at the base level using a new class of precision genetic medicines, closed at $1.45, -8.23% after hitting an intraday high of $1.58, while shares legged up to $2.17, +49.66% in the aftermarkets. The 52-wk range is $1.32-$12.89.
 
On Jan. 10, NeuBase announced  the appointment of Todd P. Branning as Chief Financial Officer (CFO). Mr. Branning has more than 25 years of experience leading corporate finance and accounting, tax, financial planning and analysis, and investor relations for several publicly traded pharmaceutical companies. Prior to joining NeuBase, Mr. Branning was CFO of Phathom Pharmaceuticals, Inc., a publicly traded late clinical-stage biopharmaceutical company. Before that, he was Senior Vice President, CFO of Amneal Pharmaceuticals, Inc., a publicly traded pharmaceutical company, where he helped to build, leverage, and optimize infrastructure following the completion of a transformational merger. Prior to joining Amneal, he was Senior Vice President, CFO of the global generic medicines division at Teva Pharmaceutical Industries Ltd., a multinational generic pharmaceuticals company, where he led the finance function and served on the leadership team responsible for managing the day-to-day operations of Teva’s largest multi-billion-dollar commercial unit. Mr. Branning has also held financial leadership roles at Allergan plc, PricewaterhouseCoopers LLP, PPG Industries, Inc., and Merck & Co., Inc. Mr. Branning received his BBA from the University of Miami and MBA from Carnegie Mellon University. Mr. Branning is also a Certified Public Accountant and has completed a CFO certification program at The Wharton School at the University of Pennsylvania.
 
On Jan. 5, Neubase announced the appointment of Eric J. Ende, M.D., to the Company’s Board of Directors. Dr. Ende has nearly 25 years of experience in advising biotechnology and life sciences companies to optimize corporate strategy and structure and maximize shareholder value. “Dr. Ende has the experience and perspective to recognize the opportunity ahead for NeuBase as it plans for the clinical development of its potentially transformational new class of precision genetic medicines,” said Dietrich A. Stephan, Ph.D., Founder, CEO and Chairman of NeuBase. “We welcome Dr. Ende’s strategic insight as we begin to scale our therapeutic candidate pipeline from our new precision genetic medicines platform technology. In addition to his broad experience, he also shares in our Company’s goal of helping millions of patients with both common and rare conditions that currently have limited or no treatment options.” “I believe NeuBase has a game-changing technology that overcomes the limitations of early precision genetic medicines by delivering mutation selectivity, repeat dosing, and systemic administration in a modular precision medicine platform with the potential to efficiently scale to treat a wide variety of diseases that are currently undruggable,” said Dr. Ende. “I look forward to working closely with NeuBase’s leadership team and Board of Directors to elevate strategy and operations in order to create exceptional value for patients and shareholders.” Dr. Ende currently is the President of Ende BioMedical Consulting Group. He also is a member of the Board of Directors of Matinas BioPharma, where he is the Chairman of the Compensation Committee and serves on the Audit and the Nomination & Governance Committees, and of Avadel plc, where he is the Chairman of the Nomination & Corporate Governance Committee and serves on the Audit and Compensation Committees. Dr. Ende previously served on the Board of Directors of Progenics (acquired by Lantheus Holdings) and Genzyme (acquired by Sanofi-Aventis for $20 billion). During his time on Genzyme’s Board of Directors, Dr. Ende was a member of the Audit and Risk Management Committees. Prior to Genzyme, Dr. Ende was a biotechnology analyst, previously serving at Merrill Lynch, BofA Securities, and Lehman Brothers. Dr. Ende received an M.B.A. from NYU Stern School of Business, an M.D. from the Icahn School of Medicine at Mount Sinai, and a B.S. in biology and psychology from Emory University.

Economic Reports

On Monday, the macroeconomic schedule delivered the preliminary IHS Markit Services PMI report for January confirmed a drop to 55 in the final reading for December, while the preliminary IHS Markit Services PMI for January dropped to 50.9. On Tuesday, the Conference Board’s Consumer Confidence Index report confirmed a decline to 113.8. The November FHFA Housing Price Index report confirmed a 1.1% M/M rise, while the November S&P Case-Shiller Home Price Index report also confirmed an 18.3% Y/Y rise.

Investing & Inspiration

  1. “But investment in space stimulates society, it stimulates it economically, it stimulates it intellectually, and it gives us all passion.” – Bill Nye
  2. “Bitcoin, in the short or even long term, may turn out be a good investment in the same way that anything that is rare can be considered valuable. Like baseball cards. Or a Picasso.” – Andrew Ross Sorkin
  3. “Life is a tragedy when seen in close-up, but a comedy in long-shot.” – Charlie Chaplin
  4. “No matter what you’re going through, there’s a light at the end of the tunnel and it may seem hard to get to it but you can do it and just keep working towards it and you’ll find the positive side of things.” – Demi Lovato
  5. “Infrastructure investment in science is an investment in jobs, in health, in economic growth and environmental solutions.” – Oren Etzioni
  6. “Educating our children and giving them the skills they need to compete in a global economy is a smart investment in our country’s future.” – Sheldon Whitehouse
  7. “Know thy self, know thy enemy. A thousand battles, a thousand victories.” – Sun Tzu
  8. “If one does not know to which port one is sailing, no wind is favorable.” – Lucius Annaeus Seneca
  9. “Beware of missing chances; otherwise it may be altogether too late some day.” – Franz Liszt
  10. “The sofa is a really important investment for anybody, and I don’t mean financially. You need to find a really great sofa that can transition with you, and you can build from there.” – Jeremiah Brent
  11. “There is no investment you can make which will pay you so well as the effort to scatter sunshine and good cheer through your establishment.” – Orison Swett Marden
  12. “Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less.” – Marie Curie
  13. “There is little that can withstand a man who can conquer himself.” – Louis XIV
  14. “In tennis, you strike a ball just after the rebound for the fastest return. It’s the same with investment.” – Masayoshi Son
  15. “A camel makes an elephant feel like a jet plane.” – Jackie Kennedy
  16. “The advance of technology is based on making it fit in so that you don’t really even notice it, so it’s part of everyday life.” – Bill Gates
  17. “Success depends upon previous preparation, and without such preparation there is sure to be failure.” – Confucius, Chinese 
  18. “Coming together is a beginning; keeping together is progress; working together is success.” – Edward Everett Hale
  19. “Never do anything against conscience even if the state demands it.”– Albert Einstein
  20. “Education is not only a ladder of opportunity, but it is also an investment in our future.” – Ed Markey
  21. “The true measure of a man is how he treats someone who can do him absolutely no good.” – Samuel Johnson
  22. “In my view, the biggest investment risk is not the volatility of prices, but whether you will suffer a permanent loss of capital. Not only is the mere drop in stock prices not risk, but it is an opportunity. Where else do you look for cheap stocks?” – Li Lu
  23. “A successful society is characterized by a rising living standard for its population, increasing investment in factories and basic infrastructure, and the generation of additional surplus, which is invested in generating new discoveries in science and technology.” – Robert Trout
  24. “The best preparation for tomorrow is doing your best today.” – H. Jackson Brown, Jr.
  25. “Friendship marks a life even more deeply than love. Love risks degenerating into obsession, friendship is never anything but sharing.” – Elie Wiesel
  26. “Investing in women’s lives is an investment in sustainable development, in human rights, in future generations – and consequently in our own long-term national interests.” – Liya Kebede
  27. “Success isn’t measured by money or power or social rank. Success is measured by your discipline and inner peace.” – Mike Ditka
  28. “No matter how many goals you have achieved, you must set your sights on a higher one.” – Jessica Savitch 
  29. “Start where you are. Use what you have. Do what you can.”– Arthur Ashe
  30. “The secret of getting ahead is getting started.” – Mark Twain
  31. “The amount of work and the amount of both physical and emotional investment it takes to get to the top.” – Drew Bledsoe

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