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Amgen, AstraZeneca Experimental Asthma Drug Shows Promise

By John F. Heerdink, Jr.

Reportedly, Drugmakers Amgen Inc. (AMGN) and AstraZeneca Plc (AZN) announced that a crucial trial found that their experimental medication tezepelumab largely reduced asthma attacks for people suffering from severe forms of the respiratory condition compared to a placebo. The patients were also receiving standard care, medium- or high-dose inhaled corticosteroids, and at least one other controller medication.

“The key thing is that tezepelumab also seems to work in the low eosinophil patient group, which could help it differentiate from Regeneron’s Dupixent and AstraZeneca’s Fasenra, both of which are indicated for the ‘eosinphilic phenotype’,” stated Mizuho analyst Salim Syed a research note, referring to currently available asthma drugs.

The drugmakers informed that tezepelumab was well received by trial patients with no major differences in safety results compared to the placebo. The drug also showed results in a subgroup of patients with low levels of a type of white blood cell, known as eosinophil, related to swelling and narrowing of airways.

Amgen informed that the full results from the trial will be presented at an upcoming medical meeting.

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(Read Original Story: Amgen, AstraZeneca say experimental asthma drug meets trial goal in Reuters)


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